Scientists create an scRNA-seq atlas of the multiple myeloma immune microenvironment across disease stages

byVIB (the Flanders Institute for Biotechnology)The MM microenvironment is characterized by the presence of T cells with an exhausted phenotype. Credit:Journal of Hematology & Oncology

Updated on: December 02,2024

Scientists create an scRNA-seq atlas of the multiple myeloma immune microenvironment across disease stages

byVIB (the Flanders Institute for Biotechnology)The MM microenvironment is characterized by the presence of T cells with an exhausted phenotype. Credit:Journal of Hematology & Oncology

Updated on:December 02,2024

Mounjaro beats Ozempic for weight loss in early trial

by Robin FosterThe diabetes drug Mounjaro prompted more weight loss among overweight and obese adults than Ozempic did in a real-world setting, researchers report.Both Mounjaro (tirzepatide) and Ozemp

Updated on: March 06,2024

Mounjaro beats Ozempic for weight loss in early trial

by Robin FosterThe diabetes drug Mounjaro prompted more weight loss among overweight and obese adults than Ozempic did in a real-world setting, researchers report.Both Mounjaro (tirzepatide) and Ozemp

Updated on:March 06,2024

Mediterranean diet improves immunotherapy response rates and progression-free survival in advanced melanoma

by United European GastroenterologyCredit: Unsplash/CC0 Public DomainEating a Mediterranean diet rich in fiber, mono-unsaturated fatty acids and polyphenols, has been associated with improved immunoth

Updated on: December 20,2023

Mediterranean diet improves immunotherapy response rates and progression-free survival in advanced melanoma

by United European GastroenterologyCredit: Unsplash/CC0 Public DomainEating a Mediterranean diet rich in fiber, mono-unsaturated fatty acids and polyphenols, has been associated with improved immunoth

Updated on:December 20,2023

Mobile 'Man Van' spots prostate cancer more quickly and cheaply than via GPs

byInstitute of Cancer ResearchCredit: The Man Van and The Royal Marsden NHS Foundation TrustMobile testing "Man Van" can diagnose prostate cancer in at-risk groups earlier and more aff

Updated on: December 01,2024

Mobile 'Man Van' spots prostate cancer more quickly and cheaply than via GPs

byInstitute of Cancer ResearchCredit: The Man Van and The Royal Marsden NHS Foundation TrustMobile testing "Man Van" can diagnose prostate cancer in at-risk groups earlier and more aff

Updated on:December 01,2024

Method that uses combination of immune cells could provide clearer prognoses

by Elin Bäckström,Swedish Research CouncilPrognostic value of CD8+T cells and CD68+CD163+macrophages revealed by comprehensive characterization of immune cell subsets in 286 therapy-

Updated on: January 04,2024

Method that uses combination of immune cells could provide clearer prognoses

by Elin Bäckström,Swedish Research CouncilPrognostic value of CD8+T cells and CD68+CD163+macrophages revealed by comprehensive characterization of immune cell subsets in 286 therapy-

Updated on:January 04,2024

Novel form of immunotherapy could revolutionize cancer treatment

by Noelle Toumey Reetz,Georgia State UniversityFig. 1: Local RT eliminates late-stage MC38 tumors in Sirpα−/− mice but not WT mice. From: Intratumoral SIRPα-deficient macrophages activate tumor

Updated on: March 25,2024

Novel form of immunotherapy could revolutionize cancer treatment

by Noelle Toumey Reetz,Georgia State UniversityFig. 1: Local RT eliminates late-stage MC38 tumors in Sirpα−/− mice but not WT mice. From: Intratumoral SIRPα-deficient macrophages activate tumor

Updated on:March 25,2024

Energy stress triggers PFKL-dependent lipid droplet-mitochondria tethering and β-oxidation to support tumor growth

Updated on: September 15,2024

Energy stress triggers PFKL-dependent lipid droplet-mitochondria tethering and β-oxidation to support tumor growth

Updated on:September 15,2024

National prostate cancer trial currently testing therapy based on molecular discovery

byCleveland ClinicCredit:Journal of Clinical Investigation(2023). DOI: 10.1172/JCI163498A new prostate cancer therapy in clinical trials could treat patients resistant to treatment t

Updated on: December 23,2023

National prostate cancer trial currently testing therapy based on molecular discovery

byCleveland ClinicCredit:Journal of Clinical Investigation(2023). DOI: 10.1172/JCI163498A new prostate cancer therapy in clinical trials could treat patients resistant to treatment t

Updated on:December 23,2023

Molecular jackhammers drill pathway to killing cancer cells  

JANUARY 19, 2024by Michelle Revels,Texas A&M University College of EngineeringResearchers have developed a technique that employs nanoscopic molecular jackhammers capable of cracking a cell&

Updated on: March 15,2024

Molecular jackhammers drill pathway to killing cancer cells  

JANUARY 19, 2024by Michelle Revels,Texas A&M University College of EngineeringResearchers have developed a technique that employs nanoscopic molecular jackhammers capable of cracking a cell&

Updated on:March 15,2024

Guideline updated for initial management of advanced prostate cancer

by Elana GotkineFor patients with noncastrate advanced prostate cancer, docetaxel, abiraterone, enzalutamide, apalutamide, or darolutamide are each recommended as standards of care with androgen depri

Updated on: January 08,2024

Guideline updated for initial management of advanced prostate cancer

by Elana GotkineFor patients with noncastrate advanced prostate cancer, docetaxel, abiraterone, enzalutamide, apalutamide, or darolutamide are each recommended as standards of care with androgen depri

Updated on:January 08,2024

Overlooked strategy shows promise for treating KRAS-mutated colon cancer

Updated on: June 14,2025

Overlooked strategy shows promise for treating KRAS-mutated colon cancer

Updated on:June 14,2025

Metabolic adaptation ensures survival of colon cancer cells

byGerman Cancer Research CenterCredit: CC0 Public DomainColon cancer cells deficient in p53, one of the most important control proteins in cell growth, activate a particular metabolic pathway to

Updated on: December 22,2023

Metabolic adaptation ensures survival of colon cancer cells

byGerman Cancer Research CenterCredit: CC0 Public DomainColon cancer cells deficient in p53, one of the most important control proteins in cell growth, activate a particular metabolic pathway to

Updated on:December 22,2023