A predictive biomarker of response to therapy in patients with microsatellite stable metastatic colorectal cancer

by Vall d'Hebron Institute of OncologyA total of 166 patients with mCRCBRAF-V600Ewere included in the study from discovery (n = 46), validation (n = 52) and control (n = 68) cohorts. WES of

Updated on: January 08,2024 6

A predictive biomarker of response to therapy in patients with microsatellite stable metastatic colorectal cancer

by Vall d'Hebron Institute of OncologyA total of 166 patients with mCRCBRAF-V600Ewere included in the study from discovery (n = 46), validation (n = 52) and control (n = 68) cohorts. WES of

Updated on:January 08,2024 6

Neoadjuvant nivolumab shows long-term benefit in patients with non–small cell lung cancer

byAmerican Association for Cancer ResearchA–D, Kaplan–Meier curves depicting the recurrence-free survival (A) and overall survival (B) for patients who underwent definitive resection after recei

Updated on: January 13,2024 13

Neoadjuvant nivolumab shows long-term benefit in patients with non–small cell lung cancer

byAmerican Association for Cancer ResearchA–D, Kaplan–Meier curves depicting the recurrence-free survival (A) and overall survival (B) for patients who underwent definitive resection after recei

Updated on:January 13,2024 13

Researchers reveal key mechanism of natural killer cell dysfunction

by Liu Jia,Chinese Academy of SciencesIntratumoral NK cells lack abundant membrane protrusions. Credit:Nature Immunology(2023). DOI: 10.1038/s41590-023-01462-9A team has revealed the

Updated on: February 20,2024 15

Researchers reveal key mechanism of natural killer cell dysfunction

by Liu Jia,Chinese Academy of SciencesIntratumoral NK cells lack abundant membrane protrusions. Credit:Nature Immunology(2023). DOI: 10.1038/s41590-023-01462-9A team has revealed the

Updated on:February 20,2024 15

New treatment for a rare and aggressive cancer improves survival rates in breakthrough clinical trial

FEBRUARY 15, 2024byQueen Mary, University of LondonCredit: Pixabay/CC0 Public DomainAn innovative treatment significantly increases the survival of people with malignant mesothelioma, a rare but

Updated on: March 29,2024 3

New treatment for a rare and aggressive cancer improves survival rates in breakthrough clinical trial

FEBRUARY 15, 2024byQueen Mary, University of LondonCredit: Pixabay/CC0 Public DomainAn innovative treatment significantly increases the survival of people with malignant mesothelioma, a rare but

Updated on:March 29,2024 3

Cancer research explores role of cytochrome oxygenases in augmenting austocystin D-mediated cytotoxicity

byTokyo University of SciencePrevious studies have suggested that austocystin D is oxidized by cytochrome P450 (CYP) oxygenases which then induces DNA damage and suppresses cell proliferation. I

Updated on: September 06,2024 0

Cancer research explores role of cytochrome oxygenases in augmenting austocystin D-mediated cytotoxicity

byTokyo University of SciencePrevious studies have suggested that austocystin D is oxidized by cytochrome P450 (CYP) oxygenases which then induces DNA damage and suppresses cell proliferation. I

Updated on:September 06,2024 0

New radiation technology raises a stir

by Netherlands Organisation for Scientific Research (NWO)Credit: Netherlands Organisation for Scientific Research (NWO)Nothing less than a breakthrough. That's how researchers at UMC Utrecht

Updated on: March 12,2024 20

New radiation technology raises a stir

by Netherlands Organisation for Scientific Research (NWO)Credit: Netherlands Organisation for Scientific Research (NWO)Nothing less than a breakthrough. That's how researchers at UMC Utrecht

Updated on:March 12,2024 20

Drug used for cocaine addiction may pave way for new treatment of advanced colon cancer

by University of OttawaMulti-omic characterization of VXN cancer-selective effect on cell functions. Credit:Nature Cancer(2024). DOI: 10.1038/s43018-024-00727-yA new, cutting-edge stu

Updated on: May 11,2024 6

Drug used for cocaine addiction may pave way for new treatment of advanced colon cancer

by University of OttawaMulti-omic characterization of VXN cancer-selective effect on cell functions. Credit:Nature Cancer(2024). DOI: 10.1038/s43018-024-00727-yA new, cutting-edge stu

Updated on:May 11,2024 6

Microbiome: Scientists highlight role of harmful gut bacteria in fever afflicting cancer patients

by Delthia Ricks , Medical XpressSchematic of histological quantification of the dense inner colonic mucus layer histologically, following PAS staining. Eight equally radially spaced sites are identif

Updated on: January 08,2024 10

Microbiome: Scientists highlight role of harmful gut bacteria in fever afflicting cancer patients

by Delthia Ricks , Medical XpressSchematic of histological quantification of the dense inner colonic mucus layer histologically, following PAS staining. Eight equally radially spaced sites are identif

Updated on:January 08,2024 10

Novel drug combination shows promise for advanced HER2-negative breast cancer

by Johns Hopkins University School of MedicineClinical efficacy.a–c, Responses as shown by a waterfall plot (a), swimmers plot (b) and spider plot (c). The dashed lines correspond to +20% a

Updated on: May 09,2024 4

Novel drug combination shows promise for advanced HER2-negative breast cancer

by Johns Hopkins University School of MedicineClinical efficacy.a–c, Responses as shown by a waterfall plot (a), swimmers plot (b) and spider plot (c). The dashed lines correspond to +20% a

Updated on:May 09,2024 4

Research tests cost-effective approach to early-cancer detection from cell-free DNA in blood samples

byUniversity of California, Los AngelesCredit: Pixabay/CC0 Public DomainEarly detection remains key to successfully treating many cancers, and early detection via cell-free DNA (cfDNA) circulati

Updated on: January 22,2024 11

Research tests cost-effective approach to early-cancer detection from cell-free DNA in blood samples

byUniversity of California, Los AngelesCredit: Pixabay/CC0 Public DomainEarly detection remains key to successfully treating many cancers, and early detection via cell-free DNA (cfDNA) circulati

Updated on:January 22,2024 11

Researchers make miniature 'bone marrows in a dish' to improve anti-cancer treatments

by University of BirminghamA cross section of a mini bone marrow organoids showing cells that produce blood platelets, in a network of blood vessels. Credit: Dr A Khan, University of BirminghamSc

Updated on: February 18,2024 17

Researchers make miniature 'bone marrows in a dish' to improve anti-cancer treatments

by University of BirminghamA cross section of a mini bone marrow organoids showing cells that produce blood platelets, in a network of blood vessels. Credit: Dr A Khan, University of BirminghamSc

Updated on:February 18,2024 17

Researchers publish the first comprehensive, 3D analysis of the complete rhabdomyosarcoma genome

by Nationwide Children's HospitalGraphical abstract. Credit:NAR Cancer(2023). DOI: 10.1093/narcan/zcad028In a paper published inNAR Cancer, researchers from the Center for C

Updated on: January 30,2024 14

Researchers publish the first comprehensive, 3D analysis of the complete rhabdomyosarcoma genome

by Nationwide Children's HospitalGraphical abstract. Credit:NAR Cancer(2023). DOI: 10.1093/narcan/zcad028In a paper published inNAR Cancer, researchers from the Center for C

Updated on:January 30,2024 14