CAR T cell immunotherapy for solid tumors? First, you have to break the cancers' sugar shield

by Delthia Ricks , Medical XpressModeling of the impact of tumor N-glycans on the targeting by CAR T cells. Left, the N-glycan decoration of tumors 1) repels CAR T cells by impeding immunological syna

Updated on: April 09,2024 20

CAR T cell immunotherapy for solid tumors? First, you have to break the cancers' sugar shield

by Delthia Ricks , Medical XpressModeling of the impact of tumor N-glycans on the targeting by CAR T cells. Left, the N-glycan decoration of tumors 1) repels CAR T cells by impeding immunological syna

Updated on:April 09,2024 20

Prostate cancer testing in Sweden—a study on cost and effectiveness

byKarolinska InstitutetShuang Hao, PhD student at the Department of Medical Epidemiology and Biostatistics. Credit: Stefan ZimmermanProstate cancer constitutes an essential public health issue,

Updated on: January 03,2024 6

Prostate cancer testing in Sweden—a study on cost and effectiveness

byKarolinska InstitutetShuang Hao, PhD student at the Department of Medical Epidemiology and Biostatistics. Credit: Stefan ZimmermanProstate cancer constitutes an essential public health issue,

Updated on:January 03,2024 6

Research: Insufficient evidence to recommend low-dose CT screening in never smokers

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainLung cancer remains the leading cause of cancer-related deaths worldwide. Detecting this disease in its early

Updated on: August 27,2024 0

Research: Insufficient evidence to recommend low-dose CT screening in never smokers

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainLung cancer remains the leading cause of cancer-related deaths worldwide. Detecting this disease in its early

Updated on:August 27,2024 0

Distinct signaling pathway identified as key driver for epithelial cancer development

by Kurt Bodenmüller,University of ZurichSide section of the skin with epidermal stem cells (green) with one particular clone in red. Cell nuclei are stained in blue, the white dashed lines indic

Updated on: August 03,2024 0

Distinct signaling pathway identified as key driver for epithelial cancer development

by Kurt Bodenmüller,University of ZurichSide section of the skin with epidermal stem cells (green) with one particular clone in red. Cell nuclei are stained in blue, the white dashed lines indic

Updated on:August 03,2024 0

Acupressure versus acupuncture—which one is better at treating sleep disturbance in patients with cancer?

byWileyCredit: CC0 Public DomainBoth acupuncture—which is invasive and involves inserted needles—and acupressure—which is non-invasive and involves mechanical pressure—can potentially help reduc

Updated on: January 15,2024 19

Acupressure versus acupuncture—which one is better at treating sleep disturbance in patients with cancer?

byWileyCredit: CC0 Public DomainBoth acupuncture—which is invasive and involves inserted needles—and acupressure—which is non-invasive and involves mechanical pressure—can potentially help reduc

Updated on:January 15,2024 19

Innovative test that detects complex DNA patterns may improve mesothelioma detection rate in blood

by Susan Murphy,Mayo ClinicStudy design. Our study involved detecting junctions that result from chromosomal rearrangements, insertions and deletions in mesothelioma in Step 1, then designing pr

Updated on: December 02,2024 0

Innovative test that detects complex DNA patterns may improve mesothelioma detection rate in blood

by Susan Murphy,Mayo ClinicStudy design. Our study involved detecting junctions that result from chromosomal rearrangements, insertions and deletions in mesothelioma in Step 1, then designing pr

Updated on:December 02,2024 0

Tracing the footprints of a tumor—genomic 'scars' allow cancer profiling

by CeMM Research Center for Molecular Medicine of the Austrian Academy of SciencesHap1 Cells stained for different DNA damages (yellow = antibody against phosphorilated ATM; red = antibody against 53B

Updated on: April 01,2024 17

Tracing the footprints of a tumor—genomic 'scars' allow cancer profiling

by CeMM Research Center for Molecular Medicine of the Austrian Academy of SciencesHap1 Cells stained for different DNA damages (yellow = antibody against phosphorilated ATM; red = antibody against 53B

Updated on:April 01,2024 17

Using mice with humanized immune systems to test cancer immunotherapies

byKobe UniversityCurrently developed cancer immunotherapies modify the interaction of cancer cells and the immune system, making drug testing targeting human cancer outside of clinical trials di

Updated on: January 26,2024 13

Using mice with humanized immune systems to test cancer immunotherapies

byKobe UniversityCurrently developed cancer immunotherapies modify the interaction of cancer cells and the immune system, making drug testing targeting human cancer outside of clinical trials di

Updated on:January 26,2024 13

New bladder cancer classification predicts treatment response

byCedars-Sinai Medical CenterStudy design and gene signatures of patients with high-risk NMIBC according to BCG response subtypes (BRS). Credit:Science Translational Medicine(2023).

Updated on: January 11,2024 10

New bladder cancer classification predicts treatment response

byCedars-Sinai Medical CenterStudy design and gene signatures of patients with high-risk NMIBC according to BCG response subtypes (BRS). Credit:Science Translational Medicine(2023).

Updated on:January 11,2024 10

Enlarged genotype-phenotype correlation for a three-base pair deletion in neurofibromatosis type 1

by Jeff Hansen,University of Alabama at BirminghamLudwine Messiaen, Ph.D., left, and Magdalena Koczkowska, Ph.D. Credit: University of Alabama at BirminghamInternational collaborative research l

Updated on: March 14,2024 12

Enlarged genotype-phenotype correlation for a three-base pair deletion in neurofibromatosis type 1

by Jeff Hansen,University of Alabama at BirminghamLudwine Messiaen, Ph.D., left, and Magdalena Koczkowska, Ph.D. Credit: University of Alabama at BirminghamInternational collaborative research l

Updated on:March 14,2024 12

Exercise protects breast cancer patients' hearts against chemotherapy drugs, new study finds

by Baker Heart & Diabetes InstituteCredit: Unsplash/CC0 Public DomainCardiovascular disease is the leading cause of mortality in breast cancer survivors. A new study out of the Baker Heart and Dia

Updated on: January 15,2024 10

Exercise protects breast cancer patients' hearts against chemotherapy drugs, new study finds

by Baker Heart & Diabetes InstituteCredit: Unsplash/CC0 Public DomainCardiovascular disease is the leading cause of mortality in breast cancer survivors. A new study out of the Baker Heart and Dia

Updated on:January 15,2024 10

Genetic testing for prostate cancer increases after introduction of point-of-care program

byWolters Kluwer HealthCredit: Unsplash/CC0 Public DomainSome patients with prostate cancer have genetic mutations that may impact their treatment. A comprehensive, on-site genetic testing progr

Updated on: January 02,2024 5

Genetic testing for prostate cancer increases after introduction of point-of-care program

byWolters Kluwer HealthCredit: Unsplash/CC0 Public DomainSome patients with prostate cancer have genetic mutations that may impact their treatment. A comprehensive, on-site genetic testing progr

Updated on:January 02,2024 5