Inhibition of histone deacetylase 2 reduces MDM2 expression and reduces tumor growth in dedifferentiated liposarcoma

by OncotargetElevated HDAC2 mRNA expression is poorly prognostic in DDLPS. (A) mRNA expression of HDAC2 and disease-free survival (DFS) data from 52 subjects with DDLPS from The Cancer Genome Atlas (T

Updated on: May 11,2024

Inhibition of histone deacetylase 2 reduces MDM2 expression and reduces tumor growth in dedifferentiated liposarcoma

by OncotargetElevated HDAC2 mRNA expression is poorly prognostic in DDLPS. (A) mRNA expression of HDAC2 and disease-free survival (DFS) data from 52 subjects with DDLPS from The Cancer Genome Atlas (T

Updated on:May 11,2024

A potential therapeutic vaccine strategy for a subset of myeloproliferative neoplasms

by Ludwig Cancer ResearchCredit: CC0 Public DomainThe cells of a subset of myeloproliferative neoplasms (MPNs), slow-growing blood cancers, have frameshift mutations in their calreticulin (CALR)

Updated on: January 29,2024

A potential therapeutic vaccine strategy for a subset of myeloproliferative neoplasms

by Ludwig Cancer ResearchCredit: CC0 Public DomainThe cells of a subset of myeloproliferative neoplasms (MPNs), slow-growing blood cancers, have frameshift mutations in their calreticulin (CALR)

Updated on:January 29,2024

Researchers find genetic pathways to individualized treatment for advanced prostate cancer

by Mayo ClinicCredit: Mayo ClinicResearchers at Mayo Clinic Center for Individualized Medicine have uncovered genetic clues to why tumors resist a specific therapy used for treating advanced pros

Updated on: June 15,2024

Researchers find genetic pathways to individualized treatment for advanced prostate cancer

by Mayo ClinicCredit: Mayo ClinicResearchers at Mayo Clinic Center for Individualized Medicine have uncovered genetic clues to why tumors resist a specific therapy used for treating advanced pros

Updated on:June 15,2024

Periostin shows promise to help fight a common form of esophageal cancer

byElsevierSchematic diagram of roles of periostin (POSTN) in the esophageal squamous cell carcinoma (ESCC) microenvironment. Direct contact with ESCC cells leads mesenchymal stem cells (MSCs) to

Updated on: April 28,2024

Periostin shows promise to help fight a common form of esophageal cancer

byElsevierSchematic diagram of roles of periostin (POSTN) in the esophageal squamous cell carcinoma (ESCC) microenvironment. Direct contact with ESCC cells leads mesenchymal stem cells (MSCs) to

Updated on:April 28,2024

Killing pancreatic cancer with T cells that supercharge themselves

by University of California, San FranciscoTherapeutic T cells engineered with tumor-triggered IL-2 production infiltrate and clear immune-excluded tumors. (A) We hypothesized that cell autonomous

Updated on: February 18,2024

Killing pancreatic cancer with T cells that supercharge themselves

by University of California, San FranciscoTherapeutic T cells engineered with tumor-triggered IL-2 production infiltrate and clear immune-excluded tumors. (A) We hypothesized that cell autonomous

Updated on:February 18,2024

Placebo pill eases cancer-related fatigue in study

by Alan MozesPatients with advanced cancer often suffer crippling fatigue, but there has been little in the way of relief for them as they battle their disease.Now, a new investigation may have landed

Updated on: March 06,2024

Placebo pill eases cancer-related fatigue in study

by Alan MozesPatients with advanced cancer often suffer crippling fatigue, but there has been little in the way of relief for them as they battle their disease.Now, a new investigation may have landed

Updated on:March 06,2024

A simple text could make the difference between life and death

by University of South AustraliaCredit: CC0 Public DomainA Ph.D. researcher from the University of South Australia is testing whether smartphone text messages can encourage cancer patients to tak

Updated on: May 23,2024

A simple text could make the difference between life and death

by University of South AustraliaCredit: CC0 Public DomainA Ph.D. researcher from the University of South Australia is testing whether smartphone text messages can encourage cancer patients to tak

Updated on:May 23,2024

Factor that doubles the risk of death from breast cancer identified

by Karolinska InstitutetMammograms showing a normal breast (left) and a breast with cancer (right). Credit: Public DomainResearchers at Karolinska Institutet in Sweden have discovered that the ri

Updated on: March 01,2024

Factor that doubles the risk of death from breast cancer identified

by Karolinska InstitutetMammograms showing a normal breast (left) and a breast with cancer (right). Credit: Public DomainResearchers at Karolinska Institutet in Sweden have discovered that the ri

Updated on:March 01,2024

3-D scaffold map to help the search for new cancer treatments

by Walter and Eliza Hall Institute of Medical ResearchScientists have solved the 3-D structure of molecular scaffold SgK223, which is known to play a critical role in the development and spread o

Updated on: March 14,2024

3-D scaffold map to help the search for new cancer treatments

by Walter and Eliza Hall Institute of Medical ResearchScientists have solved the 3-D structure of molecular scaffold SgK223, which is known to play a critical role in the development and spread o

Updated on:March 14,2024

The blind use of AI in health care can lead to invisible discrimination

by University of CopenhagenCredit: CC0 Public DomainArtificial intelligence can help health care systems under pressure allocate limited resources, but also lead to more unequal access. This is d

Updated on: April 22,2024

The blind use of AI in health care can lead to invisible discrimination

by University of CopenhagenCredit: CC0 Public DomainArtificial intelligence can help health care systems under pressure allocate limited resources, but also lead to more unequal access. This is d

Updated on:April 22,2024

Novel immune inhibitor associated with glioma progression

by Melissa Rohman,Northwestern UniversityCAFs are enriched in pediatric HGG relative to LGG and NB. (A) UMAP clustering from 21 pediatric brain samples . (B) The frequency of CAFs is a function

Updated on: March 30,2024

Novel immune inhibitor associated with glioma progression

by Melissa Rohman,Northwestern UniversityCAFs are enriched in pediatric HGG relative to LGG and NB. (A) UMAP clustering from 21 pediatric brain samples . (B) The frequency of CAFs is a function

Updated on:March 30,2024

Survival similar for Black, White prostate cancer patients in clinical trial setting

by Elana GotkineFor metastatic castration-sensitive prostate cancer (mCSPC), overall survival and progression-free survival are similar for Black and White patients receiving first- or second-generati

Updated on: February 03,2024

Survival similar for Black, White prostate cancer patients in clinical trial setting

by Elana GotkineFor metastatic castration-sensitive prostate cancer (mCSPC), overall survival and progression-free survival are similar for Black and White patients receiving first- or second-generati

Updated on:February 03,2024