Novel biomarker for immune checkpoint inhibitors identified in human lethal cancers

by Liu Jia,Chinese Academy of SciencesA model depicting how the SETD2 inactivation sensitizes cancer cells to immune checkpoint blockade through the NR2F1-STAT1 pathway. Credit: Prof. Wang Yuexi

Updated on: January 26,2024

Novel biomarker for immune checkpoint inhibitors identified in human lethal cancers

by Liu Jia,Chinese Academy of SciencesA model depicting how the SETD2 inactivation sensitizes cancer cells to immune checkpoint blockade through the NR2F1-STAT1 pathway. Credit: Prof. Wang Yuexi

Updated on:January 26,2024

'Double life' of key immune protein reveals new strategies for treating cancer and autoimmune diseases

by NYU Langone HealthCredit: CC0 Public DomainInsights into the workings of an immune cell surface receptor, called PD-1, reveal how treatments that restrict its action can potentially be strengt

Updated on: March 20,2024

'Double life' of key immune protein reveals new strategies for treating cancer and autoimmune diseases

by NYU Langone HealthCredit: CC0 Public DomainInsights into the workings of an immune cell surface receptor, called PD-1, reveal how treatments that restrict its action can potentially be strengt

Updated on:March 20,2024

Leukemia treatment breakthrough for babies

by Hayley Jarvis,Brunel UniversityComparison of K562-t(7;12) transcriptional landscape with t(7;12) patient signatures. A 177-gene signature of t(7;12)-patient gene expression extrapolated from

Updated on: February 23,2024

Leukemia treatment breakthrough for babies

by Hayley Jarvis,Brunel UniversityComparison of K562-t(7;12) transcriptional landscape with t(7;12) patient signatures. A 177-gene signature of t(7;12)-patient gene expression extrapolated from

Updated on:February 23,2024

Lymphoma patients at high risk of infections after diagnosis

byUppsala UniversityGraphical abstract. Credit:HemaSphere(2024). DOI: 10.1002/hem3.121Every year, around 100 people are affected by mantle cell lymphoma. A study at Uppsala Universit

Updated on: July 09,2024

Lymphoma patients at high risk of infections after diagnosis

byUppsala UniversityGraphical abstract. Credit:HemaSphere(2024). DOI: 10.1002/hem3.121Every year, around 100 people are affected by mantle cell lymphoma. A study at Uppsala Universit

Updated on:July 09,2024

Anti-worm drug inhibits tumor growth and spread in mice

by University of New South WalesResearchers at UNSW Sydney have discovered that a drug used for almost 40 years to treat worm infections in humans and animals can be used to inhibit melanoma grow

Updated on: March 12,2024

Anti-worm drug inhibits tumor growth and spread in mice

by University of New South WalesResearchers at UNSW Sydney have discovered that a drug used for almost 40 years to treat worm infections in humans and animals can be used to inhibit melanoma grow

Updated on:March 12,2024

New drug, WNTinib, delays tumor growth and improves survival in mouse models of children's liver cancer

by European Organisation for Research and Treatment of CancerCredit: Pixabay/CC0 Public DomainA new drug called WNTinib can delay the growth of tumors and improve survival in hepatoblastoma, a type of

Updated on: November 08,2024

New drug, WNTinib, delays tumor growth and improves survival in mouse models of children's liver cancer

by European Organisation for Research and Treatment of CancerCredit: Pixabay/CC0 Public DomainA new drug called WNTinib can delay the growth of tumors and improve survival in hepatoblastoma, a type of

Updated on:November 08,2024

New research identifies a potential treatment target for hepatoblastoma, the most common liver cancer in children

byElsevierLeft: Gross images of livers from mice transfected with β-catenin and YAP1(β-Y), β-catenin and YAP1 plus dominant negative HSF1 (dnHSF1-β-Y) and normal (control). Right: Liver to body

Updated on: January 13,2024

New research identifies a potential treatment target for hepatoblastoma, the most common liver cancer in children

byElsevierLeft: Gross images of livers from mice transfected with β-catenin and YAP1(β-Y), β-catenin and YAP1 plus dominant negative HSF1 (dnHSF1-β-Y) and normal (control). Right: Liver to body

Updated on:January 13,2024

Critical Review of the Role of Exosomal miR-519a-3p in Gastric Cancer Liver Metastasis through M2 Macrophage Polarization

Updated on: October 04,2024

Critical Review of the Role of Exosomal miR-519a-3p in Gastric Cancer Liver Metastasis through M2 Macrophage Polarization

Updated on:October 04,2024

Research: Insufficient evidence to recommend low-dose CT screening in never smokers

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainLung cancer remains the leading cause of cancer-related deaths worldwide. Detecting this disease in its early

Updated on: August 27,2024

Research: Insufficient evidence to recommend low-dose CT screening in never smokers

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainLung cancer remains the leading cause of cancer-related deaths worldwide. Detecting this disease in its early

Updated on:August 27,2024

Amivantamab-lazertinib ups survival in EGFR-mutated advanced lung cancer

by Elana GotkineFor patients with EGFR-mutated advanced non-small cell lung cancer (NSCLC), amivantamab-lazertinib yields improved progression-free survival compared with osimertinib as first-line tre

Updated on: July 08,2024

Amivantamab-lazertinib ups survival in EGFR-mutated advanced lung cancer

by Elana GotkineFor patients with EGFR-mutated advanced non-small cell lung cancer (NSCLC), amivantamab-lazertinib yields improved progression-free survival compared with osimertinib as first-line tre

Updated on:July 08,2024

Research illuminates a therapeutic strategy to induce cancer cell death

by Rachel Sauer,CU Anschutz Medical CampusCredit: CC0 Public DomainCancer is a disease driven by gene mutations. These mutated genes in cancer fall into two major categories: tumor suppressors a

Updated on: January 22,2024

Research illuminates a therapeutic strategy to induce cancer cell death

by Rachel Sauer,CU Anschutz Medical CampusCredit: CC0 Public DomainCancer is a disease driven by gene mutations. These mutated genes in cancer fall into two major categories: tumor suppressors a

Updated on:January 22,2024

Study tests new vaccine for precancerous cervical cells

by Kelsey Herbers,Vanderbilt UniversityCredit: CC0 Public DomainVanderbilt University Medical Center is participating in an international study to determine the effectiveness of a new therapeuti

Updated on: March 01,2024

Study tests new vaccine for precancerous cervical cells

by Kelsey Herbers,Vanderbilt UniversityCredit: CC0 Public DomainVanderbilt University Medical Center is participating in an international study to determine the effectiveness of a new therapeuti

Updated on:March 01,2024