Tackling resistance to HIF2 drugs with an RNA-based therapy

byUT Southwestern Medical CenterDownregulation of HIF2α by ARO-HIF2 in patient tumor biopsies. Credit: Dr. Payal KapurExpected to be diagnosed in 2% of men and 1% of women in the U.S., kidney ca

Updated on: December 28,2023

Tackling resistance to HIF2 drugs with an RNA-based therapy

byUT Southwestern Medical CenterDownregulation of HIF2α by ARO-HIF2 in patient tumor biopsies. Credit: Dr. Payal KapurExpected to be diagnosed in 2% of men and 1% of women in the U.S., kidney ca

Updated on:December 28,2023

Engineered plasma cells show long-lasting antileukemic activity in mice

byCell PressAcute myelocytic leukemia (AML). Credit: Unsplash/CC0 Public DomainResearchers show for the first time that engineered human plasma B cells can be used to treat a disease—specificall

Updated on: July 05,2024

Engineered plasma cells show long-lasting antileukemic activity in mice

byCell PressAcute myelocytic leukemia (AML). Credit: Unsplash/CC0 Public DomainResearchers show for the first time that engineered human plasma B cells can be used to treat a disease—specificall

Updated on:July 05,2024

Tumor cells' response to chemotherapy is driven by randomness, shows study

byGarvan Institute of Medical ResearchNeuroblastoma cells (cyan) growing as a tumour and the surrounding collagen matrix (magenta). The cells are expressing a biosensor (JNK-KTR) that reads out

Updated on: January 23,2024

Tumor cells' response to chemotherapy is driven by randomness, shows study

byGarvan Institute of Medical ResearchNeuroblastoma cells (cyan) growing as a tumour and the surrounding collagen matrix (magenta). The cells are expressing a biosensor (JNK-KTR) that reads out

Updated on:January 23,2024

Findings suggest common salt activates anti-tumor cells

by Friederike Gawlik, Leibniz Institute for Natural Product Research and Infection BiologyImmune cells (purple and blue) attack tumor cells (red). Highly active CD8⁺ T cells treated with sodium chlori

Updated on: September 10,2024

Findings suggest common salt activates anti-tumor cells

by Friederike Gawlik, Leibniz Institute for Natural Product Research and Infection BiologyImmune cells (purple and blue) attack tumor cells (red). Highly active CD8⁺ T cells treated with sodium chlori

Updated on:September 10,2024

Novel AI method identifies locations, interactions among genes in and around tumors

byJohns Hopkins University School of MedicineImage of a breast cancer tissue sample overlaid with visual representations of spatially interacting patterns of tumor and immune activity obtained t

Updated on: January 12,2024

Novel AI method identifies locations, interactions among genes in and around tumors

byJohns Hopkins University School of MedicineImage of a breast cancer tissue sample overlaid with visual representations of spatially interacting patterns of tumor and immune activity obtained t

Updated on:January 12,2024

Possible therapeutic approach to fight incurable blood cancer

by Technical University MunichGraphical abstract. Credit:The EMBO Journal(2022). DOI: 10.15252/embj.2022110871Multiple myeloma (MM) is the second most common type of blood cancer. It

Updated on: January 30,2024

Possible therapeutic approach to fight incurable blood cancer

by Technical University MunichGraphical abstract. Credit:The EMBO Journal(2022). DOI: 10.15252/embj.2022110871Multiple myeloma (MM) is the second most common type of blood cancer. It

Updated on:January 30,2024

Study highlights difficulty in diagnosing blood disorders, need for coordination between clinicians and pathologists

by University of Miami Leonard M. Miller School of Medicine“Our findings highlight the vital importance of seeking expert opinions from National Cancer Institute-designated cancer centers, especi

Updated on: January 30,2024

Study highlights difficulty in diagnosing blood disorders, need for coordination between clinicians and pathologists

by University of Miami Leonard M. Miller School of Medicine“Our findings highlight the vital importance of seeking expert opinions from National Cancer Institute-designated cancer centers, especi

Updated on:January 30,2024

Trial shows improvements in several clinical outcomes for men with intermediate-risk prostate cancer

by NRG OncologyCredit: Unsplash/CC0 Public DomainResults from the phase 3 NRG Oncology RTOG 0815 clinical study comparing dose-escalated radiotherapy (RT) alone to dose-escalated RT with short-term an

Updated on: January 04,2024

Trial shows improvements in several clinical outcomes for men with intermediate-risk prostate cancer

by NRG OncologyCredit: Unsplash/CC0 Public DomainResults from the phase 3 NRG Oncology RTOG 0815 clinical study comparing dose-escalated radiotherapy (RT) alone to dose-escalated RT with short-term an

Updated on:January 04,2024

Unvaccinated cancer patients with COVID seven times more likely to die than comparable patients without COVID

byRegenstrief InstituteKaplan-Meier survival estimates of overall cancer population by age group (years), Indiana, 2019-2020. Credit:JMIR Cancer(2022). DOI: 10.2196/35310Unvaccinated

Updated on: January 08,2024

Unvaccinated cancer patients with COVID seven times more likely to die than comparable patients without COVID

byRegenstrief InstituteKaplan-Meier survival estimates of overall cancer population by age group (years), Indiana, 2019-2020. Credit:JMIR Cancer(2022). DOI: 10.2196/35310Unvaccinated

Updated on:January 08,2024

'Magic bullet' takes aim at pancreatic cancer

by University of South AustraliaAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainEvery day, more than 1200 people worldwide are told they

Updated on: March 14,2024

'Magic bullet' takes aim at pancreatic cancer

by University of South AustraliaAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainEvery day, more than 1200 people worldwide are told they

Updated on:March 14,2024

High-resolution brain tumor mapping reveals possible reason why some patients don't respond to new drug

byWeizmann Institute of ScienceGraphical abstract. Credit:Cell(2024). DOI: 10.1016/j.cell.2024.03.029The cells that make up cancerous brain tumors are extremely varied and sometimes

Updated on: September 10,2024

High-resolution brain tumor mapping reveals possible reason why some patients don't respond to new drug

byWeizmann Institute of ScienceGraphical abstract. Credit:Cell(2024). DOI: 10.1016/j.cell.2024.03.029The cells that make up cancerous brain tumors are extremely varied and sometimes

Updated on:September 10,2024

Researcher pioneers method of detecting early-stage cancer: Cheaper, faster, less invasive and accurate

by Dave Raney,University of CincinnatiJiajie Diao and his collaboratorare working with UC’s Technology Transfer team to commercialize their new method for early cancer diagnosis. Credit: C

Updated on: January 30,2024

Researcher pioneers method of detecting early-stage cancer: Cheaper, faster, less invasive and accurate

by Dave Raney,University of CincinnatiJiajie Diao and his collaboratorare working with UC’s Technology Transfer team to commercialize their new method for early cancer diagnosis. Credit: C

Updated on:January 30,2024