Novel biomarker for immune checkpoint inhibitors identified in human lethal cancers

by Liu Jia,Chinese Academy of SciencesA model depicting how the SETD2 inactivation sensitizes cancer cells to immune checkpoint blockade through the NR2F1-STAT1 pathway. Credit: Prof. Wang Yuexi

Updated on: January 26,2024

Novel biomarker for immune checkpoint inhibitors identified in human lethal cancers

by Liu Jia,Chinese Academy of SciencesA model depicting how the SETD2 inactivation sensitizes cancer cells to immune checkpoint blockade through the NR2F1-STAT1 pathway. Credit: Prof. Wang Yuexi

Updated on:January 26,2024

Cancer diagnosis can be devastating, but for some it gives permission to live more radically

by Kevin Dew, Alex Broom, Chris Cunningham, Elizabeth Dennett, Kerry Chamberlain and Richard Egan,The ConversationCredit: Ivan Samkov from PexelsA diagnosis of life-limiting cancer can be overwh

Updated on: August 28,2024

Cancer diagnosis can be devastating, but for some it gives permission to live more radically

by Kevin Dew, Alex Broom, Chris Cunningham, Elizabeth Dennett, Kerry Chamberlain and Richard Egan,The ConversationCredit: Ivan Samkov from PexelsA diagnosis of life-limiting cancer can be overwh

Updated on:August 28,2024

Wide variation in bowel cancer rates after colonoscopies in England

by British Medical JournalBowel cancer survivor John Barnes. Credit: University of LeedsSubstantial variation exists between colonoscopy providers in rates of bowel cancer up to three years after

Updated on: May 11,2024

Wide variation in bowel cancer rates after colonoscopies in England

by British Medical JournalBowel cancer survivor John Barnes. Credit: University of LeedsSubstantial variation exists between colonoscopy providers in rates of bowel cancer up to three years after

Updated on:May 11,2024

Researchers discover a weakness in a rare cancer that could be exploited with drugs

by Rockefeller UniversitySome cancer cells cannot produce cholesterol, and instead build up an excess of squalene (pink)--a molecule that may help these dangerous cells thrive. Credit: Laboratory

Updated on: June 19,2024

Researchers discover a weakness in a rare cancer that could be exploited with drugs

by Rockefeller UniversitySome cancer cells cannot produce cholesterol, and instead build up an excess of squalene (pink)--a molecule that may help these dangerous cells thrive. Credit: Laboratory

Updated on:June 19,2024

Right-sided colon cancer patients have poorer survival than those with left-sided disease

by American College of SurgeonsKiller T cells surround a cancer cell. Credit: NIHORLANDO (July 23, 2018): Patients with colorectal cancer tumors on the right side may have poorer five-year surviv

Updated on: May 07,2024

Right-sided colon cancer patients have poorer survival than those with left-sided disease

by American College of SurgeonsKiller T cells surround a cancer cell. Credit: NIHORLANDO (July 23, 2018): Patients with colorectal cancer tumors on the right side may have poorer five-year surviv

Updated on:May 07,2024

Novel late-stage colorectal cancer treatment proves effective in preclinical models

by Angel Mendez,University of Minnesota Medical SchoolThe low T cells are due to exosomal, immunosuppressive miRNAs that disrupt T cell function and loss of T cells in the tumor environment. Cre

Updated on: April 29,2024

Novel late-stage colorectal cancer treatment proves effective in preclinical models

by Angel Mendez,University of Minnesota Medical SchoolThe low T cells are due to exosomal, immunosuppressive miRNAs that disrupt T cell function and loss of T cells in the tumor environment. Cre

Updated on:April 29,2024

Enlarged genotype-phenotype correlation for a three-base pair deletion in neurofibromatosis type 1

by Jeff Hansen,University of Alabama at BirminghamLudwine Messiaen, Ph.D., left, and Magdalena Koczkowska, Ph.D. Credit: University of Alabama at BirminghamInternational collaborative research l

Updated on: March 14,2024

Enlarged genotype-phenotype correlation for a three-base pair deletion in neurofibromatosis type 1

by Jeff Hansen,University of Alabama at BirminghamLudwine Messiaen, Ph.D., left, and Magdalena Koczkowska, Ph.D. Credit: University of Alabama at BirminghamInternational collaborative research l

Updated on:March 14,2024

Many breast cancer survivors do not receive genetic testing, despite being eligible

by Nicole Fawcett,University of MichiganCredit: Unsplash/CC0 Public DomainAs cancer treatment and survivorship care relies more on understanding the genetic make-up of an individual's tumor,

Updated on: July 17,2024

Many breast cancer survivors do not receive genetic testing, despite being eligible

by Nicole Fawcett,University of MichiganCredit: Unsplash/CC0 Public DomainAs cancer treatment and survivorship care relies more on understanding the genetic make-up of an individual's tumor,

Updated on:July 17,2024

Exploring how gene mutations in tumors impact radiation sensitivity

byNorthwestern UniversityHigh-content irradiation platform reproducibility for the duration of the profiling effort. The signal-to-noise ratio (SNR), in blue represents the in-plate ratio of rad

Updated on: January 07,2024

Exploring how gene mutations in tumors impact radiation sensitivity

byNorthwestern UniversityHigh-content irradiation platform reproducibility for the duration of the profiling effort. The signal-to-noise ratio (SNR), in blue represents the in-plate ratio of rad

Updated on:January 07,2024

Subtypes of fibroblasts associated with skin cancer could lead to novel immunotherapies

byMedical University of ViennaSchematic summary of spatial distribution of distinct CAF subsets in human skin cancer. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-5390

Updated on: December 01,2024

Subtypes of fibroblasts associated with skin cancer could lead to novel immunotherapies

byMedical University of ViennaSchematic summary of spatial distribution of distinct CAF subsets in human skin cancer. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-5390

Updated on:December 01,2024

Interpreting and Commenting on the Role of Oct4 in M2 Macrophage Polarization and Tumor Progression in Lung Cancer

Updated on: October 01,2024

Interpreting and Commenting on the Role of Oct4 in M2 Macrophage Polarization and Tumor Progression in Lung Cancer

Updated on:October 01,2024

Dual checkpoint inhibitor blockade shows promise as first-line and salvage therapy for Merkel cell carcinoma patients

byH. Lee Moffitt Cancer Center & Research InstituteMicrograph of a lung primary small cell carcinoma, a type of carcinoma. Credit: WikipediaMerkel cell carcinoma is a rare but aggressive for

Updated on: January 04,2024

Dual checkpoint inhibitor blockade shows promise as first-line and salvage therapy for Merkel cell carcinoma patients

byH. Lee Moffitt Cancer Center & Research InstituteMicrograph of a lung primary small cell carcinoma, a type of carcinoma. Credit: WikipediaMerkel cell carcinoma is a rare but aggressive for

Updated on:January 04,2024