New approach combines oncolytic virotherapy and adoptive T cell therapy for cancer treatment

by Bob Yirka , Medical XpressScheme of genome editing of PDL1 by eOA effectively improved virotherapy and adoptive T-cell therapy. Credit:Nature Biotechnology(2024). DOI: 10.1038/s41587-02

Updated on: March 05,2024 14

New approach combines oncolytic virotherapy and adoptive T cell therapy for cancer treatment

by Bob Yirka , Medical XpressScheme of genome editing of PDL1 by eOA effectively improved virotherapy and adoptive T-cell therapy. Credit:Nature Biotechnology(2024). DOI: 10.1038/s41587-02

Updated on:March 05,2024 14

New therapeutic avenue in the fight against chronic liver disease

by Ulsan National Institute of Science and TechnologySchematic image showing the ETP expression and survival rate in liver tissue from HCC patients. Credit: UNISTAn international team of research

Updated on: April 10,2024 18

New therapeutic avenue in the fight against chronic liver disease

by Ulsan National Institute of Science and TechnologySchematic image showing the ETP expression and survival rate in liver tissue from HCC patients. Credit: UNISTAn international team of research

Updated on:April 10,2024 18

Finally, a potential new approach against KRAS-driven lung cancer

by CU Anschutz Medical CampusAlison Bauer, PhD, and colleagues identify MUC5AC as a new target in KRAS-driven lung cancer. Credit: University of Colorado Cancer CenterThe previous decade has seen

Updated on: March 21,2024 10

Finally, a potential new approach against KRAS-driven lung cancer

by CU Anschutz Medical CampusAlison Bauer, PhD, and colleagues identify MUC5AC as a new target in KRAS-driven lung cancer. Credit: University of Colorado Cancer CenterThe previous decade has seen

Updated on:March 21,2024 10

Exercise can increase the number of immune cells in the bloodstream of cancer patients

by University of TurkuCredit: Unsplash/CC0 Public DomainExercise decreases the risk of cancer and reduces side effects of cancer treatments. In addition, it improves patients' quality of life

Updated on: February 23,2024 12

Exercise can increase the number of immune cells in the bloodstream of cancer patients

by University of TurkuCredit: Unsplash/CC0 Public DomainExercise decreases the risk of cancer and reduces side effects of cancer treatments. In addition, it improves patients' quality of life

Updated on:February 23,2024 12

Researchers leverage cell self-destruction to treat brain tumors

by University of North Carolina Health CareAn MRI showing glioblastoma pre- and post-operation. Credit: Dominique Higgins, MD, PhDGlioblastoma is the most common type of brain tumor in adults. Th

Updated on: February 23,2024 17

Researchers leverage cell self-destruction to treat brain tumors

by University of North Carolina Health CareAn MRI showing glioblastoma pre- and post-operation. Credit: Dominique Higgins, MD, PhDGlioblastoma is the most common type of brain tumor in adults. Th

Updated on:February 23,2024 17

A half-million fewer deaths from lung cancer over 40 years

by Cancer Research UKCredit: CC0 Public DomainLung cancer death rates in men have plummeted since 1979 with nearly 500,000 fewer deaths than would have been expected if the mortality rate had sta

Updated on: March 14,2024 20

A half-million fewer deaths from lung cancer over 40 years

by Cancer Research UKCredit: CC0 Public DomainLung cancer death rates in men have plummeted since 1979 with nearly 500,000 fewer deaths than would have been expected if the mortality rate had sta

Updated on:March 14,2024 20

Liquid biopsy predicts early disease progression, potential survival in patients with advanced breast cancer

by Johns Hopkins UniversityCredit: Unsplash/CC0 Public DomainA novel, automated liquid biopsy test in development by researchers at the Johns Hopkins Kimmel Cancer Center can be used to predict e

Updated on: February 20,2024 16

Liquid biopsy predicts early disease progression, potential survival in patients with advanced breast cancer

by Johns Hopkins UniversityCredit: Unsplash/CC0 Public DomainA novel, automated liquid biopsy test in development by researchers at the Johns Hopkins Kimmel Cancer Center can be used to predict e

Updated on:February 20,2024 16

Changes in RECIST tumor measures correlate linearly with survival in patients treated with checkpoint inhibitors

by SWOG Cancer Research NetworkCredit: Pixabay/CC0 Public DomainThe Response Evaluation Criteria In Solid Tumors (RECIST), used in many clinical trials to evaluate changes in tumor burden over time, c

Updated on: January 28,2024 10

Changes in RECIST tumor measures correlate linearly with survival in patients treated with checkpoint inhibitors

by SWOG Cancer Research NetworkCredit: Pixabay/CC0 Public DomainThe Response Evaluation Criteria In Solid Tumors (RECIST), used in many clinical trials to evaluate changes in tumor burden over time, c

Updated on:January 28,2024 10

Improving next-generation cancer treatments with cryoimmunotherapy

by Olivia Dimmer,Northwestern UniversityCredit:ACS Nano(2024). DOI: 10.1021/acsnano.4c05809Northwestern Medicine scientists have developed a more effective method of delivering a cut

Updated on: October 24,2024 0

Improving next-generation cancer treatments with cryoimmunotherapy

by Olivia Dimmer,Northwestern UniversityCredit:ACS Nano(2024). DOI: 10.1021/acsnano.4c05809Northwestern Medicine scientists have developed a more effective method of delivering a cut

Updated on:October 24,2024 0

Taxane-induced peripheral neuropathy in breast cancer: Frequent, clinically significant, and worse with paclitaxel

by SWOG Cancer Research NetworkCredit: Unsplash/CC0 Public DomainChemotherapy-induced peripheral neuropathy (CIPN)—nerve pain, tingling, or numbness in the hands or feet—is a common side effect of cer

Updated on: January 22,2024 12

Taxane-induced peripheral neuropathy in breast cancer: Frequent, clinically significant, and worse with paclitaxel

by SWOG Cancer Research NetworkCredit: Unsplash/CC0 Public DomainChemotherapy-induced peripheral neuropathy (CIPN)—nerve pain, tingling, or numbness in the hands or feet—is a common side effect of cer

Updated on:January 22,2024 12

Novel T cell receptor therapy shows early anti-tumor activity

byUniversity of Texas M. D. Anderson Cancer CenterCredit: CC0 Public DomainAfamitresgene autoleucel (afami-cel; formerly ADP-A2M4), an adoptive T cell receptor (TCR) therapy targeting the MAGE-A

Updated on: January 15,2024 20

Novel T cell receptor therapy shows early anti-tumor activity

byUniversity of Texas M. D. Anderson Cancer CenterCredit: CC0 Public DomainAfamitresgene autoleucel (afami-cel; formerly ADP-A2M4), an adoptive T cell receptor (TCR) therapy targeting the MAGE-A

Updated on:January 15,2024 20

Study shows INT-1B3 inhibits distant tumor metastasis and significantly prolongs survival

by Impact Journals LLCProposed mode of action of INT-1B3/1B3.INT-1B3/1B3 induces apoptosis and cell death leading to expression of DAMPs, e.g., expression of calreticulin, reduced expression of CD39 a

Updated on: August 27,2024 0

Study shows INT-1B3 inhibits distant tumor metastasis and significantly prolongs survival

by Impact Journals LLCProposed mode of action of INT-1B3/1B3.INT-1B3/1B3 induces apoptosis and cell death leading to expression of DAMPs, e.g., expression of calreticulin, reduced expression of CD39 a

Updated on:August 27,2024 0