Bowel cancer turns genetic switches on and off to outwit the immune system, new study finds

byUniversity College LondonFrameshift switching of the MSH6 C8 coding homopolymer drives stochastic loss and restoration of MSH6 expression like a molecular ON/OFF switch. Credit:Nature Ge

Updated on: July 05,2024

Bowel cancer turns genetic switches on and off to outwit the immune system, new study finds

byUniversity College LondonFrameshift switching of the MSH6 C8 coding homopolymer drives stochastic loss and restoration of MSH6 expression like a molecular ON/OFF switch. Credit:Nature Ge

Updated on:July 05,2024

Adherence to quality indicators low in chronic myeloid leukemia

by Elana Gotkine HealthDay ReporterFor newly diagnosed chronic-phase chronic myeloid leukemia (CML) patients, adherence to guideline-based quality indicators is low, according to a study published onl

Updated on: December 28,2023

Adherence to quality indicators low in chronic myeloid leukemia

by Elana Gotkine HealthDay ReporterFor newly diagnosed chronic-phase chronic myeloid leukemia (CML) patients, adherence to guideline-based quality indicators is low, according to a study published onl

Updated on:December 28,2023

Team develops tools and techniques to explore cancer signals at the subcellular level

by Jerry Grillo,Georgia Institute of TechnologyGraphical abstract. Credit:iScience(2022). DOI: 10.1016/j.isci.2022.104980This year, about 240,000 people in the U.S. will discover the

Updated on: January 08,2024

Team develops tools and techniques to explore cancer signals at the subcellular level

by Jerry Grillo,Georgia Institute of TechnologyGraphical abstract. Credit:iScience(2022). DOI: 10.1016/j.isci.2022.104980This year, about 240,000 people in the U.S. will discover the

Updated on:January 08,2024

Deadly cancers show early, detectable differences from benign tumors

by Duke University Medical CenterCredit: CC0 Public DomainDo metastatic cancer tumors "break bad" or are they "born bad"?This question is an essential mystery incancer&n

Updated on: April 09,2024

Deadly cancers show early, detectable differences from benign tumors

by Duke University Medical CenterCredit: CC0 Public DomainDo metastatic cancer tumors "break bad" or are they "born bad"?This question is an essential mystery incancer&n

Updated on:April 09,2024

Researchers analyze factors contributing to high levels of esophageal cancer in Tanzania

byThe City University of New YorkAssociations between the number of hospitals and esophageal cancer incidence with or without Dar es Salam hospital. Credit:Journal of Cancer Epidemiology&n

Updated on: January 29,2024

Researchers analyze factors contributing to high levels of esophageal cancer in Tanzania

byThe City University of New YorkAssociations between the number of hospitals and esophageal cancer incidence with or without Dar es Salam hospital. Credit:Journal of Cancer Epidemiology&n

Updated on:January 29,2024

Artificial intelligence approach may help identify melanoma survivors who face a high risk of cancer recurrence

by Katie Marquedant,Massachusetts General HospitalDistribution of recurrent melanomas in the study population. Among the 310 recurrent melanomas, 255 (82%) recurred within five years and 285 (92

Updated on: January 02,2024

Artificial intelligence approach may help identify melanoma survivors who face a high risk of cancer recurrence

by Katie Marquedant,Massachusetts General HospitalDistribution of recurrent melanomas in the study population. Among the 310 recurrent melanomas, 255 (82%) recurred within five years and 285 (92

Updated on:January 02,2024

Smoking linked to melanoma-associated death in early-stage melanoma

by Elana GotkineFor patients with clinical stage I and II melanoma, smoking is associated with an increased risk for melanoma-associated death, according to a study published online Feb. 6 inJAM

Updated on: March 05,2024

Smoking linked to melanoma-associated death in early-stage melanoma

by Elana GotkineFor patients with clinical stage I and II melanoma, smoking is associated with an increased risk for melanoma-associated death, according to a study published online Feb. 6 inJAM

Updated on:March 05,2024

Researchers discover a signaling molecule in neuroblastoma immunosuppression and aggressiveness

by Boston University School of MedicineCredit: Pixabay/CC0 Public DomainThe MYCN oncoprotein (proteins related to the growth of cancer cells) plays a key role in starting, advancing and making it

Updated on: March 20,2024

Researchers discover a signaling molecule in neuroblastoma immunosuppression and aggressiveness

by Boston University School of MedicineCredit: Pixabay/CC0 Public DomainThe MYCN oncoprotein (proteins related to the growth of cancer cells) plays a key role in starting, advancing and making it

Updated on:March 20,2024

Arf1 inhibitors promote the infiltration of cytotoxic T lymphocytes into tumors by affecting lipid metabolism

by Higher Education PressScanning electron micrograph of human T lymphocyte or T cell. Credit: NIAID/NIHIn recent years, cancer immunotherapies, represented by immune checkpoint blockade (ICB), have b

Updated on: March 30,2024

Arf1 inhibitors promote the infiltration of cytotoxic T lymphocytes into tumors by affecting lipid metabolism

by Higher Education PressScanning electron micrograph of human T lymphocyte or T cell. Credit: NIAID/NIHIn recent years, cancer immunotherapies, represented by immune checkpoint blockade (ICB), have b

Updated on:March 30,2024

Researchers map DNA damage links to onset of skin cancer, melanoma

by Washington State UniversityDNA damage resulting in multiple broken chromosomes. Credit: Wikipedia/CC BY-SA 3.0A critical link in mapping recurrent mutations of melanoma—the most serious form o

Updated on: March 12,2024

Researchers map DNA damage links to onset of skin cancer, melanoma

by Washington State UniversityDNA damage resulting in multiple broken chromosomes. Credit: Wikipedia/CC BY-SA 3.0A critical link in mapping recurrent mutations of melanoma—the most serious form o

Updated on:March 12,2024

Research team identifies a potential strategy in fight against brain cancer

by Virginia TechA microscope image of brain cancer cells, a glioma tumor type known as anaplastic astrocytoma. Credit: Wikimedia/ CC BY-SA 3.0Scientists with the Virginia Tech Carilion Research I

Updated on: May 27,2024

Research team identifies a potential strategy in fight against brain cancer

by Virginia TechA microscope image of brain cancer cells, a glioma tumor type known as anaplastic astrocytoma. Credit: Wikimedia/ CC BY-SA 3.0Scientists with the Virginia Tech Carilion Research I

Updated on:May 27,2024

Researchers find protein promotes cancer, suppresses anti-tumor immunity

by University of Texas M. D. Anderson Cancer CenterKiller T cells surround a cancer cell. Credit: NIHResearchers at The University of Texas MD Anderson Cancer Center have found that a protein inv

Updated on: June 24,2024

Researchers find protein promotes cancer, suppresses anti-tumor immunity

by University of Texas M. D. Anderson Cancer CenterKiller T cells surround a cancer cell. Credit: NIHResearchers at The University of Texas MD Anderson Cancer Center have found that a protein inv

Updated on:June 24,2024