Lost metabolic fitness of CAR NK cells is key mechanism of tumor resistance, study discovers

byUniversity of Texas M. D. Anderson Cancer CenterCAR-NK cells have a distinct single-cell transcriptome and metabolic profile. Credit:Science Advances(2023). DOI: 10.1126/sciadv.add

Updated on: January 23,2024 16

Lost metabolic fitness of CAR NK cells is key mechanism of tumor resistance, study discovers

byUniversity of Texas M. D. Anderson Cancer CenterCAR-NK cells have a distinct single-cell transcriptome and metabolic profile. Credit:Science Advances(2023). DOI: 10.1126/sciadv.add

Updated on:January 23,2024 16

Disease progression, adverse radiation effects found to be low in patients undergoing preoperative SRS

by Atrium Health Wake Forest BaptistCredit: Unsplash/CC0 Public DomainCancer that spreads to the brain from another part of the body such as lung or breast is called a metastatic brain tumor. As metas

Updated on: February 18,2024 12

Disease progression, adverse radiation effects found to be low in patients undergoing preoperative SRS

by Atrium Health Wake Forest BaptistCredit: Unsplash/CC0 Public DomainCancer that spreads to the brain from another part of the body such as lung or breast is called a metastatic brain tumor. As metas

Updated on:February 18,2024 12

Researchers renew obsolete concept by using folate for cancer drug delivery

by Raymond A. Macdougall,National Institutes of HealthImages of cancer tumor cells taken with a confocal laser scanning microscope. The top row of images show that the anti-cancer formulation de

Updated on: June 15,2024 4

Researchers renew obsolete concept by using folate for cancer drug delivery

by Raymond A. Macdougall,National Institutes of HealthImages of cancer tumor cells taken with a confocal laser scanning microscope. The top row of images show that the anti-cancer formulation de

Updated on:June 15,2024 4

Unhealthy gut sets stage for breast cancer to spread, research reveals

byUniversity of VirginiaCredit: Unsplash/CC0 Public DomainAn unhealthy gut triggers changes in normal breast tissue that helps breast cancer spread to other parts of the body, new research from

Updated on: January 16,2024 19

Unhealthy gut sets stage for breast cancer to spread, research reveals

byUniversity of VirginiaCredit: Unsplash/CC0 Public DomainAn unhealthy gut triggers changes in normal breast tissue that helps breast cancer spread to other parts of the body, new research from

Updated on:January 16,2024 19

Researchers discover protective 'acid wall' formed by cancer cells

by UTSouthwestern Medical CenterCancer cells secrete acid with a significantly lower pH than previously known by researchers, a team from UTSW shows in a new study. Credit:Nature Biom

Updated on: April 06,2024 0

Researchers discover protective 'acid wall' formed by cancer cells

by UTSouthwestern Medical CenterCancer cells secrete acid with a significantly lower pH than previously known by researchers, a team from UTSW shows in a new study. Credit:Nature Biom

Updated on:April 06,2024 0

Adding new vaccine type to leading immunotherapy dramatically reduced melanoma recurrence

by NYU Langone HealthCredit: Unsplash/CC0 Public DomainThe combination of an experimental mRNA vaccine with an immunotherapy reduced the likelihood of melanoma recurring or causing death by 44% w

Updated on: February 20,2024 15

Adding new vaccine type to leading immunotherapy dramatically reduced melanoma recurrence

by NYU Langone HealthCredit: Unsplash/CC0 Public DomainThe combination of an experimental mRNA vaccine with an immunotherapy reduced the likelihood of melanoma recurring or causing death by 44% w

Updated on:February 20,2024 15

Artificial DNA kills cancer: Hairpin-shaped DNA binds with microRNA in cancer cells to trigger an immune response

byUniversity of TokyoOncolytic DNA hairpin pairs (oHPs) are introduced to the cancer cell. When the oHPs encounter the tumor-causing overexpressed microRNA (miRNA), they unravel to connect with

Updated on: January 02,2024 8

Artificial DNA kills cancer: Hairpin-shaped DNA binds with microRNA in cancer cells to trigger an immune response

byUniversity of TokyoOncolytic DNA hairpin pairs (oHPs) are introduced to the cancer cell. When the oHPs encounter the tumor-causing overexpressed microRNA (miRNA), they unravel to connect with

Updated on:January 02,2024 8

Study uncovers role of ultraviolet radiation in development of rare leukemia in the skin

by Dana-Farber Cancer InstituteSkin tumor (top) from a representative patient with BPDCN showing infiltration by malignant cells (haematoxylin and eosin (H&E), left) expressing the pDC marker

Updated on: February 23,2024 11

Study uncovers role of ultraviolet radiation in development of rare leukemia in the skin

by Dana-Farber Cancer InstituteSkin tumor (top) from a representative patient with BPDCN showing infiltration by malignant cells (haematoxylin and eosin (H&E), left) expressing the pDC marker

Updated on:February 23,2024 11

Finally, a tool to predict response to chemotherapy before bladder cancer surgery

by CU Anschutz Medical CampusThomas Flaig, MD, and colleagues show that COXEN may predict which patients will respond to chemotherapy before bladder cancer surgery Credit: University of Colorado

Updated on: March 21,2024 20

Finally, a tool to predict response to chemotherapy before bladder cancer surgery

by CU Anschutz Medical CampusThomas Flaig, MD, and colleagues show that COXEN may predict which patients will respond to chemotherapy before bladder cancer surgery Credit: University of Colorado

Updated on:March 21,2024 20

Turncoat T cells: When exhausted, cancer-fighting T cells may switch sides

byUniversity of PittsburghGreg Delgoffe, Ph.D., associate professor of immunology at Pitt’s School of Medicine and director of the Tumor Microenvironment Center at UPMC Hillman Cancer Center. Cr

Updated on: January 02,2024 10

Turncoat T cells: When exhausted, cancer-fighting T cells may switch sides

byUniversity of PittsburghGreg Delgoffe, Ph.D., associate professor of immunology at Pitt’s School of Medicine and director of the Tumor Microenvironment Center at UPMC Hillman Cancer Center. Cr

Updated on:January 02,2024 10

Researchers develop method for separating tissue types in tumor samples

by University of North Carolina at Chapel Hill School of MedicineHematopoietic precursor cells: promyelocyte in the center, two metamyelocytes next to it and band cells from a bone marrow aspirat

Updated on: June 11,2024 5

Researchers develop method for separating tissue types in tumor samples

by University of North Carolina at Chapel Hill School of MedicineHematopoietic precursor cells: promyelocyte in the center, two metamyelocytes next to it and band cells from a bone marrow aspirat

Updated on:June 11,2024 5

Obesity as a risk factor for colorectal cancer underestimated so far, says study

byGerman Cancer Research CenterWeight Change Among Cases and Controls Within 12 Years Before Diagnosis/Interview Lower and upper hinges correspond to 25th and 75th quantile of weight changes, re

Updated on: January 16,2024 12

Obesity as a risk factor for colorectal cancer underestimated so far, says study

byGerman Cancer Research CenterWeight Change Among Cases and Controls Within 12 Years Before Diagnosis/Interview Lower and upper hinges correspond to 25th and 75th quantile of weight changes, re

Updated on:January 16,2024 12