Researchers target mutation that leads to pancreatic cancer

by Leslie Cantu,Medical University of South CarolinaCrystal structures of 12D5(K63S) in complex with KRAS(G12D)•GTPγS and with KRAS(G12D)•GDP. (A) A comparison of 12D5(K63S)–KRAS(G12D)•GTPγS (Le

Updated on: February 20,2024 20

Researchers target mutation that leads to pancreatic cancer

by Leslie Cantu,Medical University of South CarolinaCrystal structures of 12D5(K63S) in complex with KRAS(G12D)•GTPγS and with KRAS(G12D)•GDP. (A) A comparison of 12D5(K63S)–KRAS(G12D)•GTPγS (Le

Updated on:February 20,2024 20

Computational method used to directly measure tumors shows hypertranscription is ubiquitous across cancers

by Bob Yirka , Medical XpressOverview of RNA output analysis with RNAmp. (A) Hypertranscription occurs when cancer cells elevate their RNA output above normal cell levels (left). Upon RNA extraction f

Updated on: February 20,2024 19

Computational method used to directly measure tumors shows hypertranscription is ubiquitous across cancers

by Bob Yirka , Medical XpressOverview of RNA output analysis with RNAmp. (A) Hypertranscription occurs when cancer cells elevate their RNA output above normal cell levels (left). Upon RNA extraction f

Updated on:February 20,2024 19

Study maps alterations that make melanoma more severe, could lead to better therapies and diagnosis

by André Julião,FAPESPStudy design, resources and methodology. A major aim (steps 1–2) is the discovery and validation of genome-wide methylation alterations associated with the UV mutational si

Updated on: February 20,2024 11

Study maps alterations that make melanoma more severe, could lead to better therapies and diagnosis

by André Julião,FAPESPStudy design, resources and methodology. A major aim (steps 1–2) is the discovery and validation of genome-wide methylation alterations associated with the UV mutational si

Updated on:February 20,2024 11

Researchers find breast cancer protein that could predict chemotherapy sensitivity

by Hunter Medical Research InstituteThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Credit: NCI Center for

Updated on: February 20,2024 14

Researchers find breast cancer protein that could predict chemotherapy sensitivity

by Hunter Medical Research InstituteThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Credit: NCI Center for

Updated on:February 20,2024 14

Researchers uncover new clues to origins of the most common pediatric kidney cancer

by Children's Hospital Los AngelesSIX2+CITED1+ cells in hFK and WT have different transcriptional signatures. A,B) Periodic acid Schiff (PAS, left, whole image) and H&E (right, close-up i

Updated on: February 20,2024 17

Researchers uncover new clues to origins of the most common pediatric kidney cancer

by Children's Hospital Los AngelesSIX2+CITED1+ cells in hFK and WT have different transcriptional signatures. A,B) Periodic acid Schiff (PAS, left, whole image) and H&E (right, close-up i

Updated on:February 20,2024 17

A blood test that screens for multiple cancers at once promises to boost early detection

by Colin Pritchard,The ConversationDNA contains molecular patterns that indicate where in the body it came from. Credit:CNX OpenStax/Wikimedia Commons,CC BYDetecting cancer early bef

Updated on: February 20,2024 13

A blood test that screens for multiple cancers at once promises to boost early detection

by Colin Pritchard,The ConversationDNA contains molecular patterns that indicate where in the body it came from. Credit:CNX OpenStax/Wikimedia Commons,CC BYDetecting cancer early bef

Updated on:February 20,2024 13

Signs there is a problem with your prostate

by Jason HowlandProstate cancer cells. Credit: NIH Image GalleryNovember is the time of the Movember movement, which encourages growing a mustache during the month to raise awareness of men's heal

Updated on: February 20,2024 15

Signs there is a problem with your prostate

by Jason HowlandProstate cancer cells. Credit: NIH Image GalleryNovember is the time of the Movember movement, which encourages growing a mustache during the month to raise awareness of men's heal

Updated on:February 20,2024 15

Putting a dollar value on cancer survival

by University of the Sunshine CoastCredit: Pixabay/CC0 Public DomainNew University of the Sunshine Coast-led research has for the first time estimated the health care costs of Queenslanders who surviv

Updated on: February 20,2024 14

Putting a dollar value on cancer survival

by University of the Sunshine CoastCredit: Pixabay/CC0 Public DomainNew University of the Sunshine Coast-led research has for the first time estimated the health care costs of Queenslanders who surviv

Updated on:February 20,2024 14

Testing hundreds of therapeutics outside the body to predict their effectiveness against multiple myeloma

by Peter Rüegg,ETH ZurichBone-marrow cells of a multiple myeloma patient. Red cells are healthy monocytes, green and yellow are plasma cells. Credit: Berend Snijder Lab / ETH ZurichMultiple myel

Updated on: February 20,2024 14

Testing hundreds of therapeutics outside the body to predict their effectiveness against multiple myeloma

by Peter Rüegg,ETH ZurichBone-marrow cells of a multiple myeloma patient. Red cells are healthy monocytes, green and yellow are plasma cells. Credit: Berend Snijder Lab / ETH ZurichMultiple myel

Updated on:February 20,2024 14

Fighting racial bias in next-gen breast cancer screening

by Acoustical Society of AmericaVirtual imaging trials to investigate the impact of skin color on 3D optoacoustic tomography of the breast: (a) An example schematic of a 3D OAT scan (left) and a

Updated on: February 20,2024 11

Fighting racial bias in next-gen breast cancer screening

by Acoustical Society of AmericaVirtual imaging trials to investigate the impact of skin color on 3D optoacoustic tomography of the breast: (a) An example schematic of a 3D OAT scan (left) and a

Updated on:February 20,2024 11

Study offers proof of concept for treating pediatric brain tumors with immunotherapy

by Children’s Hospital of PhiladelphiaGPC2 is expressed in pediatric brain tumors. (A) GPC2 RNA sequencing data across OpenPBTA pediatric brain tumors cohorts. Neuroblastoma GPC2 RNA sequencing includ

Updated on: February 20,2024 14

Study offers proof of concept for treating pediatric brain tumors with immunotherapy

by Children’s Hospital of PhiladelphiaGPC2 is expressed in pediatric brain tumors. (A) GPC2 RNA sequencing data across OpenPBTA pediatric brain tumors cohorts. Neuroblastoma GPC2 RNA sequencing includ

Updated on:February 20,2024 14

Researchers develop priorities for interventions to address health disparities in lung nodule management

by Boston University School of MedicineCascade-of-care framework for identifying potential areas for intervention to reduce disparities in lung nodule evaluation. This figure shows each step of a

Updated on: February 20,2024 19

Researchers develop priorities for interventions to address health disparities in lung nodule management

by Boston University School of MedicineCascade-of-care framework for identifying potential areas for intervention to reduce disparities in lung nodule evaluation. This figure shows each step of a

Updated on:February 20,2024 19