Denosumab linked to severe hypocalcemia in dialysis-dependent seniors

by Elana GotkineFor female dialysis-dependent patients aged 65 years or older treated for osteoporosis, denosumab is associated with an increased incidence of severe or very severe hypocalcemia, accor

Updated on: March 26,2024 19

Denosumab linked to severe hypocalcemia in dialysis-dependent seniors

by Elana GotkineFor female dialysis-dependent patients aged 65 years or older treated for osteoporosis, denosumab is associated with an increased incidence of severe or very severe hypocalcemia, accor

Updated on:March 26,2024 19

Antibody-based therapy eliminates circulating tumor cells in mouse models of breast and pancreatic cancer

by Katie Marquedant,Massachusetts General Hospital(A) Schema for the mouse models of neoadjuvant placebo or 23C6 treatment. (B) Tumor volume measurements of 4T1 orthotopic mammary gland tumors i

Updated on: December 25,2023 6

Antibody-based therapy eliminates circulating tumor cells in mouse models of breast and pancreatic cancer

by Katie Marquedant,Massachusetts General Hospital(A) Schema for the mouse models of neoadjuvant placebo or 23C6 treatment. (B) Tumor volume measurements of 4T1 orthotopic mammary gland tumors i

Updated on:December 25,2023 6

FDA approves new treatment for advanced melanoma

by Robin FosterThe U.S. Food and Drug Administration has approved a novel treatment for advanced melanoma, the most deadly form of skin cancer.Amtagvi, made by Iovance Biotherapeutics Inc., becomes th

Updated on: March 22,2024 16

FDA approves new treatment for advanced melanoma

by Robin FosterThe U.S. Food and Drug Administration has approved a novel treatment for advanced melanoma, the most deadly form of skin cancer.Amtagvi, made by Iovance Biotherapeutics Inc., becomes th

Updated on:March 22,2024 16

Researchers make unexpected discovery in how pancreatic cancer spreads

by Alison Satake,Mayo ClinicCredit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.113042How cancer spreads or metastasizes is a big question for cancer researchers and patients. Mayo

Updated on: December 30,2023 15

Researchers make unexpected discovery in how pancreatic cancer spreads

by Alison Satake,Mayo ClinicCredit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.113042How cancer spreads or metastasizes is a big question for cancer researchers and patients. Mayo

Updated on:December 30,2023 15

Combining immunotherapy with KRAS inhibitor eliminates advanced KRAS-mutant pancreatic cancer in preclinical models

by University of Texas M. D. Anderson Cancer CenterAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainResearchers at The University of Texa

Updated on: January 30,2024 17

Combining immunotherapy with KRAS inhibitor eliminates advanced KRAS-mutant pancreatic cancer in preclinical models

by University of Texas M. D. Anderson Cancer CenterAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainResearchers at The University of Texa

Updated on:January 30,2024 17

Weight loss surgery for obese women prevents womb cancer

by Mike Addelman,University of ManchesterA study of women who had gastric sleeve or bypass surgery for obesity has found that precancerous tissue in their womb reverted to normal tissue when the

Updated on: December 18,2023 11

Weight loss surgery for obese women prevents womb cancer

by Mike Addelman,University of ManchesterA study of women who had gastric sleeve or bypass surgery for obesity has found that precancerous tissue in their womb reverted to normal tissue when the

Updated on:December 18,2023 11

The role of p53 as a target for novel cancer therapies

by Erika Rindsjö,Karolinska InstitutetComplex interplay between TP53-mutant cancer cells and their microenvironment. Credit:Nature Reviews Clinical Oncology(2023). DOI: 10.1038/s4157

Updated on: December 30,2023 16

The role of p53 as a target for novel cancer therapies

by Erika Rindsjö,Karolinska InstitutetComplex interplay between TP53-mutant cancer cells and their microenvironment. Credit:Nature Reviews Clinical Oncology(2023). DOI: 10.1038/s4157

Updated on:December 30,2023 16

Endometrial cancer: New insights into a deadly disparity

byMemorial Sloan Kettering Cancer CenterCredit: Pixabay/CC0 Public DomainEndometrial cancer—which develops in the lining of the uterus (womb) and is sometimes called uterine cancer—is on the ris

Updated on: December 28,2023 6

Endometrial cancer: New insights into a deadly disparity

byMemorial Sloan Kettering Cancer CenterCredit: Pixabay/CC0 Public DomainEndometrial cancer—which develops in the lining of the uterus (womb) and is sometimes called uterine cancer—is on the ris

Updated on:December 28,2023 6

New urine-based test shows promise in making cervical cancer screening more accessible and less invasive

byWaseda UniversityDetection of HPV16 E7 oncoproteins in urine samples using ultrasensitive enzyme-linked immunosorbent assay Image caption: Researchers have now validated a noninvasive method f

Updated on: July 09,2024 0

New urine-based test shows promise in making cervical cancer screening more accessible and less invasive

byWaseda UniversityDetection of HPV16 E7 oncoproteins in urine samples using ultrasensitive enzyme-linked immunosorbent assay Image caption: Researchers have now validated a noninvasive method f

Updated on:July 09,2024 0

Cardiopulmonary fitness is key for helping breast cancer patients manage post-diagnosis symptoms, say researchers

by Adrianna MacPherson,University of AlbertaIndependent associations between health-related fitness variables and breast cancer-related symptoms in newly diagnosed breast cancer patients. (A) Mo

Updated on: October 26,2024 0

Cardiopulmonary fitness is key for helping breast cancer patients manage post-diagnosis symptoms, say researchers

by Adrianna MacPherson,University of AlbertaIndependent associations between health-related fitness variables and breast cancer-related symptoms in newly diagnosed breast cancer patients. (A) Mo

Updated on:October 26,2024 0

Avelumab plus axitinib significantly improve progression-free survival in untreated renal cell carcinoma

byEuropean Society for Medical OncologyCredit: CC0 Public DomainA combination of the immune checkpoint blocker, avelumab, plus the tyrosine kinase inhibitor (TKI), axitinib, significantly improv

Updated on: December 18,2023 19

Avelumab plus axitinib significantly improve progression-free survival in untreated renal cell carcinoma

byEuropean Society for Medical OncologyCredit: CC0 Public DomainA combination of the immune checkpoint blocker, avelumab, plus the tyrosine kinase inhibitor (TKI), axitinib, significantly improv

Updated on:December 18,2023 19

FDA approves Abecma for relapsed, refractory multiple myeloma

by Lori SolomonThe U.S. Food and Drug Administration has approved Abecma (idecabtagene vicleucel) as a personalized CAR T-cell therapy for triple-class exposed relapsed or refractory multiple myeloma.

Updated on: April 28,2024 0

FDA approves Abecma for relapsed, refractory multiple myeloma

by Lori SolomonThe U.S. Food and Drug Administration has approved Abecma (idecabtagene vicleucel) as a personalized CAR T-cell therapy for triple-class exposed relapsed or refractory multiple myeloma.

Updated on:April 28,2024 0