Novel genetic signature that can predict some kinds of breast cancer is identified

by Maria Fernanda Ziegler,FAPESPBlood vessels from the retina of a mouse with retinopathy, normal and pathological vessels stained green and red respectively. Credit: Ricardo GiordanoResearchers

Updated on: December 22,2023 12

Novel genetic signature that can predict some kinds of breast cancer is identified

by Maria Fernanda Ziegler,FAPESPBlood vessels from the retina of a mouse with retinopathy, normal and pathological vessels stained green and red respectively. Credit: Ricardo GiordanoResearchers

Updated on:December 22,2023 12

Faulty DNA repair may lead to BRCA-linked cancers

byWeill Cornell Medical CollegeStalled replication forks (yellow arrows) are detected at the BRCA1 gene in cells containing a BRCA1 germline mutation. Credit: Weill Cornell MedicineError-prone D

Updated on: December 20,2023 10

Faulty DNA repair may lead to BRCA-linked cancers

byWeill Cornell Medical CollegeStalled replication forks (yellow arrows) are detected at the BRCA1 gene in cells containing a BRCA1 germline mutation. Credit: Weill Cornell MedicineError-prone D

Updated on:December 20,2023 10

When combined, a novel LSD1 inhibitor and an existing therapy enhance each other's anti-cancer effects

by Jaclyn Dunne,Medical University of South CarolinaGraphical abstract. Credit:European Journal of Medicinal Chemistry(2022). DOI: 10.1016/j.ejmech.2022.114818A Medical University of

Updated on: December 20,2023 10

When combined, a novel LSD1 inhibitor and an existing therapy enhance each other's anti-cancer effects

by Jaclyn Dunne,Medical University of South CarolinaGraphical abstract. Credit:European Journal of Medicinal Chemistry(2022). DOI: 10.1016/j.ejmech.2022.114818A Medical University of

Updated on:December 20,2023 10

Insurance disparities ID'd in diagnosis of late-stage melanoma

For nonelderly adults in the United States, having Medicaid or no health insurance is associated with increased odds of being diagnosed with late-stage melanoma compared with having private insurance,

Updated on: December 22,2023 14

Insurance disparities ID'd in diagnosis of late-stage melanoma

For nonelderly adults in the United States, having Medicaid or no health insurance is associated with increased odds of being diagnosed with late-stage melanoma compared with having private insurance,

Updated on:December 22,2023 14

How cancer cells die: Scientists explore new pathways of pyroptosis, killer kin of apoptosis

by Delthia Ricks , Medical XpressLymphoid BLaER1 cells undergo PANX1-dominant lysis. (A to C) BLaER1 cells were treated with topoisomerase poisons doxorubicin (2 μM) or etoposide (50 μM) for 24 hours.

Updated on: December 18,2023 8

How cancer cells die: Scientists explore new pathways of pyroptosis, killer kin of apoptosis

by Delthia Ricks , Medical XpressLymphoid BLaER1 cells undergo PANX1-dominant lysis. (A to C) BLaER1 cells were treated with topoisomerase poisons doxorubicin (2 μM) or etoposide (50 μM) for 24 hours.

Updated on:December 18,2023 8

Unlocking the potential of melatonin: A promising epigenetic weapon against cancer

In a recent study published in the journalAntioxidants, researchers discuss the potential role of melatonin in regulating deoxyribonucleic acid (DNA) methylation.Study:Melatonin: A P

Updated on: October 28,2023 7

Unlocking the potential of melatonin: A promising epigenetic weapon against cancer

In a recent study published in the journalAntioxidants, researchers discuss the potential role of melatonin in regulating deoxyribonucleic acid (DNA) methylation.Study:Melatonin: A P

Updated on:October 28,2023 7

Mutations in donors' stem cells may cause problems for cancer patients

byWashington University School of MedicineA new study from Washington University School of Medicine in St. Louis suggests that bone marrow -- or blood stem cells -- from healthy donors can harbo

Updated on: December 22,2023 23

Mutations in donors' stem cells may cause problems for cancer patients

byWashington University School of MedicineA new study from Washington University School of Medicine in St. Louis suggests that bone marrow -- or blood stem cells -- from healthy donors can harbo

Updated on:December 22,2023 23

Novel combination therapy has similar response rates to chemotherapy for high-risk luminal B breast cancer

byAmerican Association for Cancer ResearchNeoadjuvant treatment with the CDK4/6 inhibitor ribociclib (Kisqali) and the aromatase inhibitor letrozole (Femara) produced response rates similar to m

Updated on: December 22,2023 10

Novel combination therapy has similar response rates to chemotherapy for high-risk luminal B breast cancer

byAmerican Association for Cancer ResearchNeoadjuvant treatment with the CDK4/6 inhibitor ribociclib (Kisqali) and the aromatase inhibitor letrozole (Femara) produced response rates similar to m

Updated on:December 22,2023 10

Radiation/cisplatin combination established as standard of care for HPV+ oral cancer

byAmerican Society for Radiation OncologyCombinations of radiation and chemotherapy drugs have been shown to cure HPV-related head and neck cancer with a high success rate. A new phase III trial

Updated on: December 18,2023 21

Radiation/cisplatin combination established as standard of care for HPV+ oral cancer

byAmerican Society for Radiation OncologyCombinations of radiation and chemotherapy drugs have been shown to cure HPV-related head and neck cancer with a high success rate. A new phase III trial

Updated on:December 18,2023 21

Cancer stem cells use 'normal' genes in abnormal ways

by Garth Sundem,CU Anschutz Medical CampusMayumi Fajita, MD, PhD and colleagues show that CDK1 interacts with Sox2 to keep cancer stem cells 'stemmy'. Credit: University of Colorado Canc

Updated on: December 18,2023 19

Cancer stem cells use 'normal' genes in abnormal ways

by Garth Sundem,CU Anschutz Medical CampusMayumi Fajita, MD, PhD and colleagues show that CDK1 interacts with Sox2 to keep cancer stem cells 'stemmy'. Credit: University of Colorado Canc

Updated on:December 18,2023 19

Study uncovers the role of NETO2-mediated regulation in melanoma progression

by Frontiers JournalsCredit:Frontiers of Medicine(2023). DOI: 10.1007/s11684-022-0935-0Cong Peng and others at the Department of Dermatology, Xiangya Hospital, Central South University, Ch

Updated on: August 27,2024 0

Study uncovers the role of NETO2-mediated regulation in melanoma progression

by Frontiers JournalsCredit:Frontiers of Medicine(2023). DOI: 10.1007/s11684-022-0935-0Cong Peng and others at the Department of Dermatology, Xiangya Hospital, Central South University, Ch

Updated on:August 27,2024 0

Blood test biopsy for kids with brain tumors is simple, safe way to see if treatment is working

byUniversity of California, San FranciscoA new blood test for children with brain tumors offers a safer approach than surgical biopsies and may allow doctors to measure the effectiveness of trea

Updated on: December 18,2023 13

Blood test biopsy for kids with brain tumors is simple, safe way to see if treatment is working

byUniversity of California, San FranciscoA new blood test for children with brain tumors offers a safer approach than surgical biopsies and may allow doctors to measure the effectiveness of trea

Updated on:December 18,2023 13