Novel combination therapy has similar response rates to chemotherapy for high-risk luminal B breast cancer

byAmerican Association for Cancer ResearchNeoadjuvant treatment with the CDK4/6 inhibitor ribociclib (Kisqali) and the aromatase inhibitor letrozole (Femara) produced response rates similar to m

Updated on: December 22,2023

Novel combination therapy has similar response rates to chemotherapy for high-risk luminal B breast cancer

byAmerican Association for Cancer ResearchNeoadjuvant treatment with the CDK4/6 inhibitor ribociclib (Kisqali) and the aromatase inhibitor letrozole (Femara) produced response rates similar to m

Updated on:December 22,2023

Artificial intelligence tracks down leukemia

byGerman Center for Neurodegenerative DiseasesCredit: CC0 Public DomainArtificial intelligence can detect one of the most common forms of blood cancer—acute myeloid leukemia (AML)—with high reli

Updated on: December 22,2023

Artificial intelligence tracks down leukemia

byGerman Center for Neurodegenerative DiseasesCredit: CC0 Public DomainArtificial intelligence can detect one of the most common forms of blood cancer—acute myeloid leukemia (AML)—with high reli

Updated on:December 22,2023

When combined, a novel LSD1 inhibitor and an existing therapy enhance each other's anti-cancer effects

by Jaclyn Dunne,Medical University of South CarolinaGraphical abstract. Credit:European Journal of Medicinal Chemistry(2022). DOI: 10.1016/j.ejmech.2022.114818A Medical University of

Updated on: December 20,2023

When combined, a novel LSD1 inhibitor and an existing therapy enhance each other's anti-cancer effects

by Jaclyn Dunne,Medical University of South CarolinaGraphical abstract. Credit:European Journal of Medicinal Chemistry(2022). DOI: 10.1016/j.ejmech.2022.114818A Medical University of

Updated on:December 20,2023

NELSON trial protocol more sensitive than NLST and may increase the benefits of lung cancer screening

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainThe protocol used to screen and detect lung cancer in the NELSON Trial is more sensitive than the protocol use

Updated on: December 18,2023

NELSON trial protocol more sensitive than NLST and may increase the benefits of lung cancer screening

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainThe protocol used to screen and detect lung cancer in the NELSON Trial is more sensitive than the protocol use

Updated on:December 18,2023

Survival in Primary Hemophagocytic Lymphohistiocytosis Can Be as High as 100%

February 2024Lara C. Pullen, PhDResults from a contemporary standard-of-care study of patients with primary hemophagocytic lymphohistiocytosis (pHLH) reveal that firstline etoposide-based therapy is m

Updated on: February 18,2024

Survival in Primary Hemophagocytic Lymphohistiocytosis Can Be as High as 100%

February 2024Lara C. Pullen, PhDResults from a contemporary standard-of-care study of patients with primary hemophagocytic lymphohistiocytosis (pHLH) reveal that firstline etoposide-based therapy is m

Updated on:February 18,2024

Gene mutations should be tested routinely for ovarian cancer, say scientists

by Mike Addelman,University of ManchesterCredit: Unsplash/CC0 Public DomainScientists from The University of Manchester have shown that testing for two gene families linked to a lifetime epithel

Updated on: December 27,2023

Gene mutations should be tested routinely for ovarian cancer, say scientists

by Mike Addelman,University of ManchesterCredit: Unsplash/CC0 Public DomainScientists from The University of Manchester have shown that testing for two gene families linked to a lifetime epithel

Updated on:December 27,2023

Unraveling predisposition in bilateral Wilms tumor

bySt. Jude Children's Research HospitalSummary of Proposed Mechanisms for Bilateral Wilms tumor development. Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-43730-0Ch

Updated on: December 30,2023

Unraveling predisposition in bilateral Wilms tumor

bySt. Jude Children's Research HospitalSummary of Proposed Mechanisms for Bilateral Wilms tumor development. Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-43730-0Ch

Updated on:December 30,2023

Mechanism for silencing gene expression targets the culprit behind a deadly liver cancer

by Sanford M. Simon,Rockefeller UniversityASGR1 in FLC. (A) RNA expression analysis of ASGR1 across patient samples. (B) Immunofluorescence of ASGR1 in tumor-adjacent healthy liver, primary tumo

Updated on: March 20,2024

Mechanism for silencing gene expression targets the culprit behind a deadly liver cancer

by Sanford M. Simon,Rockefeller UniversityASGR1 in FLC. (A) RNA expression analysis of ASGR1 across patient samples. (B) Immunofluorescence of ASGR1 in tumor-adjacent healthy liver, primary tumo

Updated on:March 20,2024

Study shows protein inhibitor as potential treatment approach for common mutations found in non-Hodgkin lymphomas

byUniversity of Texas M. D. Anderson Cancer CenterCancer cell during cell division. Credit: National Institutes of HealthA study at The University of Texas MD Anderson Cancer Center demonstrated

Updated on: December 22,2023

Study shows protein inhibitor as potential treatment approach for common mutations found in non-Hodgkin lymphomas

byUniversity of Texas M. D. Anderson Cancer CenterCancer cell during cell division. Credit: National Institutes of HealthA study at The University of Texas MD Anderson Cancer Center demonstrated

Updated on:December 22,2023

Pathogenesis to management of hepatocellular carcinoma

by Impact JournalsMolecular pathways and targeted therapeutics in hepatocellular carcinoma. Abbreviations: APC: antigen presenting cell; AXL is a cell surface receptor tyrosine kinase, part of the TAM

Updated on: December 22,2023

Pathogenesis to management of hepatocellular carcinoma

by Impact JournalsMolecular pathways and targeted therapeutics in hepatocellular carcinoma. Abbreviations: APC: antigen presenting cell; AXL is a cell surface receptor tyrosine kinase, part of the TAM

Updated on:December 22,2023

Study finds less invasive, safer option for removing benign pancreatic tumors

byBoston University School of MedicineCredit: Pixabay/CC0 Public DomainInsulinomas are abnormal tumors, usually benign, that grow in the beta cells of the pancreas. Insulinomas make extra insuli

Updated on: April 28,2024

Study finds less invasive, safer option for removing benign pancreatic tumors

byBoston University School of MedicineCredit: Pixabay/CC0 Public DomainInsulinomas are abnormal tumors, usually benign, that grow in the beta cells of the pancreas. Insulinomas make extra insuli

Updated on:April 28,2024

Researchers identify path to prevent cognitive decline after radiation

by Kelsie Smith Hayduk,University of Rochester Medical CenterCredit: Pixabay/CC0 Public DomainResearchers at the Del Monte Institute for Neuroscience at the University of Rochester find that mic

Updated on: January 09,2024

Researchers identify path to prevent cognitive decline after radiation

by Kelsie Smith Hayduk,University of Rochester Medical CenterCredit: Pixabay/CC0 Public DomainResearchers at the Del Monte Institute for Neuroscience at the University of Rochester find that mic

Updated on:January 09,2024