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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Faster genomics-based diagnosis may accelerate targeted treatment of patients with myeloid neoplasms

Faster genomics-based diagnosis may accelerate targeted treatment of patients with myeloid neoplasms

byElsevierA: Comparison of clinical assay variant allele fraction (VAF) and Ion Torrent Genexus VAF showed high correlation (r2= 0.98) across a broad range of VAFs, including both in-house

Faster genomics-based diagnosis may accelerate targeted treatment of patients with myeloid neoplasms

byElsevierA: Comparison of clinical assay variant allele fraction (VAF) and Ion Torrent Genexus VAF showed high correlation (r2= 0.98) across a broad range of VAFs, including both in-house
Scientists develop first bone marrow model that supports human stem cells

Scientists develop first bone marrow model that supports human stem cells

byUniversity of GlasgowSchematic of the bone marrow (BM) niche microenvironment. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-50054-0Scientists have created the first

Scientists develop first bone marrow model that supports human stem cells

byUniversity of GlasgowSchematic of the bone marrow (BM) niche microenvironment. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-50054-0Scientists have created the first
Estrogen may facilitate the growth of liver metastases in non-sex-specific cancers

Estrogen may facilitate the growth of liver metastases in non-sex-specific cancers

byMcGill UniversityCancer cell during cell division. Credit: National Institutes of HealthIt is known that the tumor microenvironment plays an important role in the progression of cancer. But co

Estrogen may facilitate the growth of liver metastases in non-sex-specific cancers

byMcGill UniversityCancer cell during cell division. Credit: National Institutes of HealthIt is known that the tumor microenvironment plays an important role in the progression of cancer. But co
Differences in animal biology can affect cancer drug development

Differences in animal biology can affect cancer drug development

byWeill Cornell Medical CollegeDifferential co-occurrence and effects of KRAS, TP53 and LKB1 mutations on human and mouse LUADs (A) MSK Impact oncoprint of co-occurrence of KRAS, TP53 and LKB1 m

Differences in animal biology can affect cancer drug development

byWeill Cornell Medical CollegeDifferential co-occurrence and effects of KRAS, TP53 and LKB1 mutations on human and mouse LUADs (A) MSK Impact oncoprint of co-occurrence of KRAS, TP53 and LKB1 m
CAR T cell therapy for T cell lymphoma shows promise in phase I trial

CAR T cell therapy for T cell lymphoma shows promise in phase I trial

by Molly Chiu,Baylor College of MedicineCredit: Pixabay/CC0 Public DomainResearchers at the Center for Cell and Gene Therapy at Baylor College of Medicine, Texas Children's Hospital, and Hou

CAR T cell therapy for T cell lymphoma shows promise in phase I trial

by Molly Chiu,Baylor College of MedicineCredit: Pixabay/CC0 Public DomainResearchers at the Center for Cell and Gene Therapy at Baylor College of Medicine, Texas Children's Hospital, and Hou
When cells cycle fast, cancer gets a jumpstart

When cells cycle fast, cancer gets a jumpstart

byYale UniversityCredit: CC0 Public DomainThe progression of cancer has been studied extensively, and the key steps in this journey have been well mapped, at least in some solid tumors: Lesions

When cells cycle fast, cancer gets a jumpstart

byYale UniversityCredit: CC0 Public DomainThe progression of cancer has been studied extensively, and the key steps in this journey have been well mapped, at least in some solid tumors: Lesions
Using SPEDOX-6 to provide targeted cancer treatment and protect heart cells

Using SPEDOX-6 to provide targeted cancer treatment and protect heart cells

by International Society for Stem Cell ResearchSPEDOX-6 causes less damage to heart cells than dox. Left: stem cell derived heart cells treated with dox. Right: stem cell derived heart cells treated w

Using SPEDOX-6 to provide targeted cancer treatment and protect heart cells

by International Society for Stem Cell ResearchSPEDOX-6 causes less damage to heart cells than dox. Left: stem cell derived heart cells treated with dox. Right: stem cell derived heart cells treated w
Immunotherapy improves survival in metastatic or recurrent head and neck cancer

Immunotherapy improves survival in metastatic or recurrent head and neck cancer

byEuropean Society for Medical OncologyProf Barbara Burtness, Yale School of Medicine and Co-Director, Development Therapeutics Research Program, Yale Cancer Center, New Haven, US, study author.

Immunotherapy improves survival in metastatic or recurrent head and neck cancer

byEuropean Society for Medical OncologyProf Barbara Burtness, Yale School of Medicine and Co-Director, Development Therapeutics Research Program, Yale Cancer Center, New Haven, US, study author.
Trial shows timing matters when adding immunotherapy to chemoradiation for limited-stage small cell lung cancer

Trial shows timing matters when adding immunotherapy to chemoradiation for limited-stage small cell lung cancer

byAmerican Society for Radiation OncologyCredit: Pixabay/CC0 Public DomainPeople with limited-stage small cell lung cancer may benefit from adding immunotherapy to chemoradiation, but not if bot

Trial shows timing matters when adding immunotherapy to chemoradiation for limited-stage small cell lung cancer

byAmerican Society for Radiation OncologyCredit: Pixabay/CC0 Public DomainPeople with limited-stage small cell lung cancer may benefit from adding immunotherapy to chemoradiation, but not if bot
Researchers look at post menopause as key factor in endometrial cancer

Researchers look at post menopause as key factor in endometrial cancer

byMayo ClinicCredit: CC0 Public DomainEndometrial cancer is the most common gynecological malignancy in the U.S. and the fourth most common cancer among women. In addition, endometrial cancer in

Researchers look at post menopause as key factor in endometrial cancer

byMayo ClinicCredit: CC0 Public DomainEndometrial cancer is the most common gynecological malignancy in the U.S. and the fourth most common cancer among women. In addition, endometrial cancer in
Gut microbiome can play key role in response to CAR-T cell cancer immunotherapy

Gut microbiome can play key role in response to CAR-T cell cancer immunotherapy

byGerman Cancer Research CenterCredit: Unsplash/CC0 Public DomainScientists from German Cancer Research Center (DKFZ), together with colleagues from Germany, Israel, and the U.S., have found tha

Gut microbiome can play key role in response to CAR-T cell cancer immunotherapy

byGerman Cancer Research CenterCredit: Unsplash/CC0 Public DomainScientists from German Cancer Research Center (DKFZ), together with colleagues from Germany, Israel, and the U.S., have found tha