Free tool simplifies cancer research

byKarolinska InstitutetCredit: CC0 Public DomainEvery cell contains a vast number of proteins, each of which has a specific function, for example, as a receptor for another molecule or an enzyme

Updated on: December 22,2023 18

Free tool simplifies cancer research

byKarolinska InstitutetCredit: CC0 Public DomainEvery cell contains a vast number of proteins, each of which has a specific function, for example, as a receptor for another molecule or an enzyme

Updated on:December 22,2023 18

Scientists uncover novel DNA repair mechanism for key cancer target

byThe Francis Crick InstituteGraphical Abstract. Credit:Molecular Cell(2022). DOI: 10.1016/j.molcel.2022.11.008Scientists at the Francis Crick Institute, in collaboration with Artios

Updated on: December 27,2023 9

Scientists uncover novel DNA repair mechanism for key cancer target

byThe Francis Crick InstituteGraphical Abstract. Credit:Molecular Cell(2022). DOI: 10.1016/j.molcel.2022.11.008Scientists at the Francis Crick Institute, in collaboration with Artios

Updated on:December 27,2023 9

Scientists develop a peptide that targets lung tumors and delivers therapeutics inside cells

bySRI InternationalMonomeric and tetrameric MGS4 have similar binding, internalization and subcellular location. a, Binding and internalization of tetrameric MGS4_V1 and monomeric MGS4_V2 on liv

Updated on: December 27,2023 10

Scientists develop a peptide that targets lung tumors and delivers therapeutics inside cells

bySRI InternationalMonomeric and tetrameric MGS4 have similar binding, internalization and subcellular location. a, Binding and internalization of tetrameric MGS4_V1 and monomeric MGS4_V2 on liv

Updated on:December 27,2023 10

The architectural role of p53: Early 3D chromatin remodeling to trigger cellular stress response

byJosep Carreras Leukaemia Research InstituteTAD dynamics along p53 activation. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-46666-1The simplest explanation of cancer

Updated on: April 28,2024 0

The architectural role of p53: Early 3D chromatin remodeling to trigger cellular stress response

byJosep Carreras Leukaemia Research InstituteTAD dynamics along p53 activation. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-46666-1The simplest explanation of cancer

Updated on:April 28,2024 0

New model identifies drugs that shouldn't be taken together

by Massachusetts Institute of TechnologyCredit: CC0 Public DomainAny drug that is taken orally must pass through the lining of the digestive tract. Transporter proteins found on cells that line t

Updated on: March 21,2024 13

New model identifies drugs that shouldn't be taken together

by Massachusetts Institute of TechnologyCredit: CC0 Public DomainAny drug that is taken orally must pass through the lining of the digestive tract. Transporter proteins found on cells that line t

Updated on:March 21,2024 13

A promising treatment for ovarian cancer

by Erin Matthews,Canadian Light SourceOvary. Credit: Public DomainOver 20,000 women across the U.S. and Canada are diagnosed with ovarian cancer annually. The symptoms of this disease are often

Updated on: March 12,2024 10

A promising treatment for ovarian cancer

by Erin Matthews,Canadian Light SourceOvary. Credit: Public DomainOver 20,000 women across the U.S. and Canada are diagnosed with ovarian cancer annually. The symptoms of this disease are often

Updated on:March 12,2024 10

Ultrasound activated microbubbles enhance the activity of standard of care therapeutics in pancreatic cancer

byTranslational Genomics Research InstituteUltrasound administration setup and drug dosing timeline. A. Photograph of the ultrasound administration setup; B. Schematic depiction of the ultrasoun

Updated on: December 19,2023 10

Ultrasound activated microbubbles enhance the activity of standard of care therapeutics in pancreatic cancer

byTranslational Genomics Research InstituteUltrasound administration setup and drug dosing timeline. A. Photograph of the ultrasound administration setup; B. Schematic depiction of the ultrasoun

Updated on:December 19,2023 10

Targeting treatment resistance in chronic lymphocytic leukemia with a compound that goes beyond current BTK inhibitors

by University of Miami Leonard M. Miller School of MedicineCredit: Unsplash/CC0 Public DomainNew research from Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Me

Updated on: June 11,2024 4

Targeting treatment resistance in chronic lymphocytic leukemia with a compound that goes beyond current BTK inhibitors

by University of Miami Leonard M. Miller School of MedicineCredit: Unsplash/CC0 Public DomainNew research from Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Me

Updated on:June 11,2024 4

Relapse Following CAR T-cell Therapy Linked to Poor OS in Relapsed/Refractory Myeloma

August 27, 2022Lisa AstorRelapse following treatment with BCMA-directed CAR T-cell therapy was associated with poor survival outcomes in patients with relapsed/refractory multiple myeloma.Multiple Mye

Updated on: October 24,2023 31

Relapse Following CAR T-cell Therapy Linked to Poor OS in Relapsed/Refractory Myeloma

August 27, 2022Lisa AstorRelapse following treatment with BCMA-directed CAR T-cell therapy was associated with poor survival outcomes in patients with relapsed/refractory multiple myeloma.Multiple Mye

Updated on:October 24,2023 31

Polygenic risk scores may miss the mark when predicting aggressive prostate cancers

by Justin Jackson , Medical XpressCredit: Pixabay/CC0 Public DomainAccording to a research letter published inJAMA Internal Medicine, prostate cancer screening frequently results in biopsies tha

Updated on: December 21,2023 10

Polygenic risk scores may miss the mark when predicting aggressive prostate cancers

by Justin Jackson , Medical XpressCredit: Pixabay/CC0 Public DomainAccording to a research letter published inJAMA Internal Medicine, prostate cancer screening frequently results in biopsies tha

Updated on:December 21,2023 10

Protein movement reveals brain tumor's weak spot

by Annika Lund,Karolinska InstitutetCredit: Unsplash/CC0 Public DomainProteins do not have a single shape, but are more like dynamic robots. But—how do they actually move? And what does this tel

Updated on: December 20,2023 6

Protein movement reveals brain tumor's weak spot

by Annika Lund,Karolinska InstitutetCredit: Unsplash/CC0 Public DomainProteins do not have a single shape, but are more like dynamic robots. But—how do they actually move? And what does this tel

Updated on:December 20,2023 6

Scientists learn what women know—and don't know—about breast density and cancer risk

byDartmouth-Hitchcock Medical CenterMammograms showing a normal breast (left) and a breast with cancer (right). Credit: Public DomainBreast density is an important risk factor for breast cancer

Updated on: December 22,2023 23

Scientists learn what women know—and don't know—about breast density and cancer risk

byDartmouth-Hitchcock Medical CenterMammograms showing a normal breast (left) and a breast with cancer (right). Credit: Public DomainBreast density is an important risk factor for breast cancer

Updated on:December 22,2023 23