Third-generation anti-CD19 CAR T-cells show efficacy without neurotoxicity in B-cell lymphoma phase 1 clinical trial

byMalaghan Institute of Medical ResearchMalaghan Institute GMP lab where CAR T-cells were manufactured for the phase 1 trial. Credit: Malaghan Institute of Medical ResearchThe Malaghan Institute

Updated on: January 26,2024

Third-generation anti-CD19 CAR T-cells show efficacy without neurotoxicity in B-cell lymphoma phase 1 clinical trial

byMalaghan Institute of Medical ResearchMalaghan Institute GMP lab where CAR T-cells were manufactured for the phase 1 trial. Credit: Malaghan Institute of Medical ResearchThe Malaghan Institute

Updated on:January 26,2024

Incidence of early-onset gastric cancer increasing in the U.S.

(HealthDay)—The incidence of early-onset gastric cancer has been increasing in the United States, and it seems to be distinct clinically and genetically from late-onset gastric cancer, according to a

Updated on: December 22,2023

Incidence of early-onset gastric cancer increasing in the U.S.

(HealthDay)—The incidence of early-onset gastric cancer has been increasing in the United States, and it seems to be distinct clinically and genetically from late-onset gastric cancer, according to a

Updated on:December 22,2023

Combination of chemo and diabetes drugs shows potential for treating Ewing sarcoma

byHouston MethodistStephen T. Wong, Ph.D., Associate Director, Cores, Biostatistics and BioinformaticsHouston Methodist Cancer Center. Credit: Houston MethodistEwing sarcoma, an aggressive tumor

Updated on: December 22,2023

Combination of chemo and diabetes drugs shows potential for treating Ewing sarcoma

byHouston MethodistStephen T. Wong, Ph.D., Associate Director, Cores, Biostatistics and BioinformaticsHouston Methodist Cancer Center. Credit: Houston MethodistEwing sarcoma, an aggressive tumor

Updated on:December 22,2023

Financial impacts of cancer found to intensify disease burden among German patients

byEuropean Society for Medical OncologyA study conducted in Germany draws attention to the fact that the socio-economic burden of cancer is real in Europe too, and not only in the context of the

Updated on: December 18,2023

Financial impacts of cancer found to intensify disease burden among German patients

byEuropean Society for Medical OncologyA study conducted in Germany draws attention to the fact that the socio-economic burden of cancer is real in Europe too, and not only in the context of the

Updated on:December 18,2023

Shutting down backup genes leads to cancer remission in mice

by Jim Lynch,University of MichiganAbhinav Achreja, PhD, Research Fellow at the University of Michigan Biomedical Engineering and Deepak Nagrath, Ph.D. Associate Professor of Biomedical Engineer

Updated on: December 22,2023

Shutting down backup genes leads to cancer remission in mice

by Jim Lynch,University of MichiganAbhinav Achreja, PhD, Research Fellow at the University of Michigan Biomedical Engineering and Deepak Nagrath, Ph.D. Associate Professor of Biomedical Engineer

Updated on:December 22,2023

Marker found for condition that causes numerous tumors

by Cathy Frisinger,UT Southwestern Medical CenterCutaneous neurofibromas cover the back of a patient. Credit: UTSWUT Southwestern researchers have made a major advance in uncovering the biology

Updated on: December 18,2023

Marker found for condition that causes numerous tumors

by Cathy Frisinger,UT Southwestern Medical CenterCutaneous neurofibromas cover the back of a patient. Credit: UTSWUT Southwestern researchers have made a major advance in uncovering the biology

Updated on:December 18,2023

BRAF Mutation: Cancer Types, Testing, Treatment

BRAF Mutation: Cancer Types, Testing, TreatmentRole of BRAF mutations in melanoma, lung cancer, and moreByLynne Eldridge, MDUpdated on October 14, 2022Medically reviewed byOliv

Updated on: January 28,2024

BRAF Mutation: Cancer Types, Testing, Treatment

BRAF Mutation: Cancer Types, Testing, TreatmentRole of BRAF mutations in melanoma, lung cancer, and moreByLynne Eldridge, MDUpdated on October 14, 2022Medically reviewed byOliv

Updated on:January 28,2024

Breakaway breast cancer cells can travel to the brain: Scientists plot path in quest to block entry

by Delthia Ricks , Medical XpressIn vitro characterization of in vivo / ex vivo-derived 4T1 metastatic cell lines. (A) Schematic representation of the procedure used to generate the 4T1-BM2 metastatic

Updated on: December 22,2023

Breakaway breast cancer cells can travel to the brain: Scientists plot path in quest to block entry

by Delthia Ricks , Medical XpressIn vitro characterization of in vivo / ex vivo-derived 4T1 metastatic cell lines. (A) Schematic representation of the procedure used to generate the 4T1-BM2 metastatic

Updated on:December 22,2023

Acid reflux drugs may have negative side effects for breast cancer survivors

by Emily Caldwell,The Ohio State UniversityAcid reflux drugs that are sometimes recommended to ease stomach problems during cancer treatment may have an unintended side effect: impairment of bre

Updated on: December 23,2023

Acid reflux drugs may have negative side effects for breast cancer survivors

by Emily Caldwell,The Ohio State UniversityAcid reflux drugs that are sometimes recommended to ease stomach problems during cancer treatment may have an unintended side effect: impairment of bre

Updated on:December 23,2023

Low income linked to high recurrence risk, poorer survival in women with ER-positive breast cancer

by Roswell Park Comprehensive Cancer CenterCredit: Unsplash/CC0 Public DomainPatients with early-stage estrogen receptor-positive breast cancer who live in low-income neighborhoods are likelier to hav

Updated on: December 20,2023

Low income linked to high recurrence risk, poorer survival in women with ER-positive breast cancer

by Roswell Park Comprehensive Cancer CenterCredit: Unsplash/CC0 Public DomainPatients with early-stage estrogen receptor-positive breast cancer who live in low-income neighborhoods are likelier to hav

Updated on:December 20,2023

Pinpointing the prevalence of mismatch repair (MMR)-deficient rectal adenocarcinomas

byBrigham and Women's HospitalCredit: Pixabay/CC0 Public DomainA widely-circulated clinical trial published earlier this year in theNew England Journal of Medicine (NEJM)describe

Updated on: December 26,2023

Pinpointing the prevalence of mismatch repair (MMR)-deficient rectal adenocarcinomas

byBrigham and Women's HospitalCredit: Pixabay/CC0 Public DomainA widely-circulated clinical trial published earlier this year in theNew England Journal of Medicine (NEJM)describe

Updated on:December 26,2023

Researchers find the key to genome-modifying drugs' sensitivity in malignant blood diseases

by Josep Carreras Leukaemia Research InstituteImpact of azacitidine on global DNA methylation patterns and definition of EPIAZA signature in patients with MDS. (A) Study design and workflow. (B,

Updated on: March 20,2024

Researchers find the key to genome-modifying drugs' sensitivity in malignant blood diseases

by Josep Carreras Leukaemia Research InstituteImpact of azacitidine on global DNA methylation patterns and definition of EPIAZA signature in patients with MDS. (A) Study design and workflow. (B,

Updated on:March 20,2024