Multiple myeloma survival down with high ADAR1 RNA expression

(HealthDay)—Amplification of the inflammation-responsive RNA editase adenosine deaminase acting on RNA (ADAR)1 gene is associated with reduced survival in multiple myeloma (MM), according to a study p

Updated on: March 30,2024

Multiple myeloma survival down with high ADAR1 RNA expression

(HealthDay)—Amplification of the inflammation-responsive RNA editase adenosine deaminase acting on RNA (ADAR)1 gene is associated with reduced survival in multiple myeloma (MM), according to a study p

Updated on:March 30,2024

Two for the price of one: Mechanistic insights lead to drug repositioning

by University of TsukubaMolecular mechanism at a glance. SFN binds with SKP1 to sequester it in cytoplasm,resulting in the obstruction of SCFFBW7 598 complex formation. Oncoproteins including cyc

Updated on: May 23,2024

Two for the price of one: Mechanistic insights lead to drug repositioning

by University of TsukubaMolecular mechanism at a glance. SFN binds with SKP1 to sequester it in cytoplasm,resulting in the obstruction of SCFFBW7 598 complex formation. Oncoproteins including cyc

Updated on:May 23,2024

Researchers detect a loophole in chronic lymphocytic leukemia treatment

by Rockefeller University PressThe adhesive protein CD49d (red) is present on the surface of these adherent chronic lymphocytic leukemia cells. Credit: Tissino et al., 2018A team of researchers i

Updated on: March 01,2024

Researchers detect a loophole in chronic lymphocytic leukemia treatment

by Rockefeller University PressThe adhesive protein CD49d (red) is present on the surface of these adherent chronic lymphocytic leukemia cells. Credit: Tissino et al., 2018A team of researchers i

Updated on:March 01,2024

Researchers clarify role of mutations in glioblastoma

by University of North Carolina at Chapel Hill School of MedicineLaboratory models with a mutated PIK3CA gene showed characteristics of gliomas. Credit: McNeill, RS, et al.,PLOS ONE.Researc

Updated on: June 24,2024

Researchers clarify role of mutations in glioblastoma

by University of North Carolina at Chapel Hill School of MedicineLaboratory models with a mutated PIK3CA gene showed characteristics of gliomas. Credit: McNeill, RS, et al.,PLOS ONE.Researc

Updated on:June 24,2024

More than half a million breast cancer deaths averted in the US over three decades

by WileyMammograms showing a normal breast (left) and a breast with cancer (right). Credit: Public DomainLatest U.S. estimates indicate that since 1989, hundreds of thousands of women's lives

Updated on: March 01,2024

More than half a million breast cancer deaths averted in the US over three decades

by WileyMammograms showing a normal breast (left) and a breast with cancer (right). Credit: Public DomainLatest U.S. estimates indicate that since 1989, hundreds of thousands of women's lives

Updated on:March 01,2024

Doctors and nurses reluctant to recommend e-cigarettes to cancer patients

by National Cancer Research InstituteCredit: CC0 Public DomainTwenty-nine per cent of health professionals would not recommend e-cigarettes to cancer patients who already smoke, according to research

Updated on: May 17,2024

Doctors and nurses reluctant to recommend e-cigarettes to cancer patients

by National Cancer Research InstituteCredit: CC0 Public DomainTwenty-nine per cent of health professionals would not recommend e-cigarettes to cancer patients who already smoke, according to research

Updated on:May 17,2024

Stress-tolerant cells shown to drive tumor initiation in pancreatic cancer

by University of California - San DiegoTumor-initiating cells (blue) produce an extracellular matrix containing fibronectin (pink) which gives them increased stress tolerance, drug resistance and

Updated on: February 23,2024

Stress-tolerant cells shown to drive tumor initiation in pancreatic cancer

by University of California - San DiegoTumor-initiating cells (blue) produce an extracellular matrix containing fibronectin (pink) which gives them increased stress tolerance, drug resistance and

Updated on:February 23,2024

Fake organs guide the way for 'impossible' cancer surgery

by Mark Michaud,University of Rochester Medical CenterAhmed Ghazi, M.D., holds a lifelike model of Anthony Camnetar's kidney. Credit: University of Rochester Medical CenterAnthony Camnetar r

Updated on: March 06,2024

Fake organs guide the way for 'impossible' cancer surgery

by Mark Michaud,University of Rochester Medical CenterAhmed Ghazi, M.D., holds a lifelike model of Anthony Camnetar's kidney. Credit: University of Rochester Medical CenterAnthony Camnetar r

Updated on:March 06,2024

Social vulnerability tied to worse pediatric head and neck cancer outcomes

by Lori SolomonAmong pediatric patients with head and neck cancers (HNCs), increasing social vulnerability is associated with significant decreases in receipt of care and survival time, according to a

Updated on: January 04,2024

Social vulnerability tied to worse pediatric head and neck cancer outcomes

by Lori SolomonAmong pediatric patients with head and neck cancers (HNCs), increasing social vulnerability is associated with significant decreases in receipt of care and survival time, according to a

Updated on:January 04,2024

Potential melanoma target bypasses therapeutic resistance to immune checkpoint blockers

by Jeff Hansen,University of Alabama at BirminghamConstitutive activation of JAK1/2 in IFNγR1KOmelanoma cells. a Identification of a JAK1/2-centric network of activated protein tyrosine ki

Updated on: January 02,2024

Potential melanoma target bypasses therapeutic resistance to immune checkpoint blockers

by Jeff Hansen,University of Alabama at BirminghamConstitutive activation of JAK1/2 in IFNγR1KOmelanoma cells. a Identification of a JAK1/2-centric network of activated protein tyrosine ki

Updated on:January 02,2024

Researchers find link between obesity and blood cancer

by Jackie Maupin,Indiana University School of MedicineCredit: Unsplash/CC0 Public DomainIndiana University School of Medicine researchers studying clonal hematopoiesis of indeterminate potential

Updated on: February 01,2024

Researchers find link between obesity and blood cancer

by Jackie Maupin,Indiana University School of MedicineCredit: Unsplash/CC0 Public DomainIndiana University School of Medicine researchers studying clonal hematopoiesis of indeterminate potential

Updated on:February 01,2024

Costs of $259,324 incurred by adolescent, young adult cancer survivors

by Elana GotkineAdolescent and young adult (AYA) cancer survivors incur costs of $259,324 over their lifetime, according to a study published online Feb. 24 in theJournal of Clinical Oncology.Su

Updated on: January 02,2024

Costs of $259,324 incurred by adolescent, young adult cancer survivors

by Elana GotkineAdolescent and young adult (AYA) cancer survivors incur costs of $259,324 over their lifetime, according to a study published online Feb. 24 in theJournal of Clinical Oncology.Su

Updated on:January 02,2024