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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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A potential therapeutic vaccine strategy for a subset of myeloproliferative neoplasms

A potential therapeutic vaccine strategy for a subset of myeloproliferative neoplasms

by Ludwig Cancer ResearchCredit: CC0 Public DomainThe cells of a subset of myeloproliferative neoplasms (MPNs), slow-growing blood cancers, have frameshift mutations in their calreticulin (CALR)

A potential therapeutic vaccine strategy for a subset of myeloproliferative neoplasms

by Ludwig Cancer ResearchCredit: CC0 Public DomainThe cells of a subset of myeloproliferative neoplasms (MPNs), slow-growing blood cancers, have frameshift mutations in their calreticulin (CALR)
Multiple myeloma survival down with high ADAR1 RNA expression

Multiple myeloma survival down with high ADAR1 RNA expression

(HealthDay)—Amplification of the inflammation-responsive RNA editase adenosine deaminase acting on RNA (ADAR)1 gene is associated with reduced survival in multiple myeloma (MM), according to a study p

Multiple myeloma survival down with high ADAR1 RNA expression

(HealthDay)—Amplification of the inflammation-responsive RNA editase adenosine deaminase acting on RNA (ADAR)1 gene is associated with reduced survival in multiple myeloma (MM), according to a study p
Resistance of mammary fibrosis to immune checkpoint therapy linked to macrophage infiltration, Wnt pathway expression

Resistance of mammary fibrosis to immune checkpoint therapy linked to macrophage infiltration, Wnt pathway expression

by Impact Journals LLCWnt pathway expression in tumors from NeuT/ATTAC mice. Credit: 2022 Yuan et al.A new research paper titled "Resistance of MMTV-NeuT/ATTAC mice to anti-PD-1 immune checkpoint

Resistance of mammary fibrosis to immune checkpoint therapy linked to macrophage infiltration, Wnt pathway expression

by Impact Journals LLCWnt pathway expression in tumors from NeuT/ATTAC mice. Credit: 2022 Yuan et al.A new research paper titled "Resistance of MMTV-NeuT/ATTAC mice to anti-PD-1 immune checkpoint
Repurposing existing FDA-approved inhibitors may provide new treatment approach for ovarian cancer

Repurposing existing FDA-approved inhibitors may provide new treatment approach for ovarian cancer

by The Wistar InstituteCredit: The Wistar InstituteWistar researchers have found rationale for repurposing a class of antitumor compounds called HDAC inhibitors, already approved by the FDA for t

Repurposing existing FDA-approved inhibitors may provide new treatment approach for ovarian cancer

by The Wistar InstituteCredit: The Wistar InstituteWistar researchers have found rationale for repurposing a class of antitumor compounds called HDAC inhibitors, already approved by the FDA for t
Tumors backfire on chemotherapy

Tumors backfire on chemotherapy

by Ecole Polytechnique Federale de LausanneEndothelial cells (blue/grey) internalizing exosomes (red) released from chemotherapy-treated tumors. Credit: C. Cianciaruso/I. Keklikoglou/EPFLSome pat

Tumors backfire on chemotherapy

by Ecole Polytechnique Federale de LausanneEndothelial cells (blue/grey) internalizing exosomes (red) released from chemotherapy-treated tumors. Credit: C. Cianciaruso/I. Keklikoglou/EPFLSome pat
Study discovers triple immunotherapy combination as possible treatment for pancreatic cancer

Study discovers triple immunotherapy combination as possible treatment for pancreatic cancer

by University of Texas M. D. Anderson Cancer CenterAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainResearchers at The University of Texa

Study discovers triple immunotherapy combination as possible treatment for pancreatic cancer

by University of Texas M. D. Anderson Cancer CenterAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainResearchers at The University of Texa
New treatment approach for prostate cancer could stop resistance in its tracks

New treatment approach for prostate cancer could stop resistance in its tracks

bySanford Burnham Prebys Medical Discovery InstituteProstate cancer cells. Credit: NIH Image GalleryFor the first time, researchers have discovered that prostate cancer can be killed by targetin

New treatment approach for prostate cancer could stop resistance in its tracks

bySanford Burnham Prebys Medical Discovery InstituteProstate cancer cells. Credit: NIH Image GalleryFor the first time, researchers have discovered that prostate cancer can be killed by targetin
Boosting physical activity and curbing sitting time are highly likely to lower breast cancer risk

Boosting physical activity and curbing sitting time are highly likely to lower breast cancer risk

by British Medical JournalCredit: Pixabay/CC0 Public DomainBoosting physical activity levels and curbing sitting time are highly likely to lower breast cancer risk, finds research designed to str

Boosting physical activity and curbing sitting time are highly likely to lower breast cancer risk

by British Medical JournalCredit: Pixabay/CC0 Public DomainBoosting physical activity levels and curbing sitting time are highly likely to lower breast cancer risk, finds research designed to str
A brief cognitive behavioral therapy appears promising for head and neck cancer survivors

A brief cognitive behavioral therapy appears promising for head and neck cancer survivors

by Medical University of South CarolinaA microvascular reconstructive surgeon by training, Dr. Evan Graboyes became interested in alleviating body-image distress when he saw how much his head and

A brief cognitive behavioral therapy appears promising for head and neck cancer survivors

by Medical University of South CarolinaA microvascular reconstructive surgeon by training, Dr. Evan Graboyes became interested in alleviating body-image distress when he saw how much his head and
High ambient temperature in pregnancy associated with childhood leukemia

High ambient temperature in pregnancy associated with childhood leukemia

byYale UniversityCredit: Pixabay/CC0 Public DomainAs climate change warms the planet, high ambient temperatures are expected to be more common and intense over the coming decades in the U.S. and

High ambient temperature in pregnancy associated with childhood leukemia

byYale UniversityCredit: Pixabay/CC0 Public DomainAs climate change warms the planet, high ambient temperatures are expected to be more common and intense over the coming decades in the U.S. and
Skin cancer rewires its energy systems to spread more efficiently, finds study

Skin cancer rewires its energy systems to spread more efficiently, finds study

by Queen Mary, University of LondonDifferent modes of migration and mitochondrial metabolism.a,bOxygen consumption rate (OCR) from cells embedded in a 3D collagen I matrix (n = 

Skin cancer rewires its energy systems to spread more efficiently, finds study

by Queen Mary, University of LondonDifferent modes of migration and mitochondrial metabolism.a,bOxygen consumption rate (OCR) from cells embedded in a 3D collagen I matrix (n = 
New method eradicates deadly brain tumors by 'starving' them of energy source

New method eradicates deadly brain tumors by 'starving' them of energy source

byTel Aviv UniversityDr. Lior Mayo and students. Credit: Tel Aviv UniversityA groundbreaking study at Tel Aviv University effectively eradicated glioblastoma, a highly lethal type of brain cance

New method eradicates deadly brain tumors by 'starving' them of energy source

byTel Aviv UniversityDr. Lior Mayo and students. Credit: Tel Aviv UniversityA groundbreaking study at Tel Aviv University effectively eradicated glioblastoma, a highly lethal type of brain cance