Researchers unveil the origin of second pediatric cancers and chemotherapy-induced mutations in healthy tissues

byInstitute for Research in Biomedicine (IRB Barcelona)The origin of second solid tumors of cases 3 (A–D) and 4 (E–F). A, Eight years after the development of NB, the child presented with MRT. B

Updated on: March 30,2024

Researchers unveil the origin of second pediatric cancers and chemotherapy-induced mutations in healthy tissues

byInstitute for Research in Biomedicine (IRB Barcelona)The origin of second solid tumors of cases 3 (A–D) and 4 (E–F). A, Eight years after the development of NB, the child presented with MRT. B

Updated on:March 30,2024

Combined epigenetic and immunotherapy for blastic and classical mantle cell lymphoma

by Impact JournalsMechanisms of SCR resistance and characterization of the CD20 negative MCL cell lines 353. Credit: LeBlanc et al,Oncotarget(2022). DOI: 10.18632/oncotarget.28258A new res

Updated on: January 02,2024

Combined epigenetic and immunotherapy for blastic and classical mantle cell lymphoma

by Impact JournalsMechanisms of SCR resistance and characterization of the CD20 negative MCL cell lines 353. Credit: LeBlanc et al,Oncotarget(2022). DOI: 10.18632/oncotarget.28258A new res

Updated on:January 02,2024

COVID-19 pandemic could have led to 20,000 prostate cancer diagnosis being missed

byUniversity of SurreyObserved and predicted trends over time from January 2015 to July 2023 showing rates per 100 000 registered adult men (A) prostate cancer incidence, (B) prevalence, and (C)

Updated on: March 30,2024

COVID-19 pandemic could have led to 20,000 prostate cancer diagnosis being missed

byUniversity of SurreyObserved and predicted trends over time from January 2015 to July 2023 showing rates per 100 000 registered adult men (A) prostate cancer incidence, (B) prevalence, and (C)

Updated on:March 30,2024

Colon cancer is increasing in younger Coloradans even as death rate drops for people over 55

by Meg Wingerter, The Denver PostCredit: Pixabay/CC0 Public DomainIn 2020, the most recent year with data on cancer cases, 452 people under the age of 55 received a colorectal cancer diagnosis in Colo

Updated on: March 30,2024

Colon cancer is increasing in younger Coloradans even as death rate drops for people over 55

by Meg Wingerter, The Denver PostCredit: Pixabay/CC0 Public DomainIn 2020, the most recent year with data on cancer cases, 452 people under the age of 55 received a colorectal cancer diagnosis in Colo

Updated on:March 30,2024

Illuminating tumor cells with dark proteins

by Columbia UniversityRibosome roadblock effect: comparing the AMD1 tail sequence, poly(A) and the XBP1 stalling sequence. a–e, Reporter constructs shown on the left were transfected into HEK293T

Updated on: February 19,2024

Illuminating tumor cells with dark proteins

by Columbia UniversityRibosome roadblock effect: comparing the AMD1 tail sequence, poly(A) and the XBP1 stalling sequence. a–e, Reporter constructs shown on the left were transfected into HEK293T

Updated on:February 19,2024

Potential strategy for treating liver cancer: Study discovers signaling pathway mediated by extracellular vesicles

by The University of Hong KongCirculating sEVs from HCC patients promote angiogenesis in vitro and in vivo. A) Tube formation assay of HUVECs pretreated with PBS, circulating sEVs of control indi

Updated on: February 18,2024

Potential strategy for treating liver cancer: Study discovers signaling pathway mediated by extracellular vesicles

by The University of Hong KongCirculating sEVs from HCC patients promote angiogenesis in vitro and in vivo. A) Tube formation assay of HUVECs pretreated with PBS, circulating sEVs of control indi

Updated on:February 18,2024

ACO enrollment ups appropriateness of CA screening

(HealthDay)—Enrollment in the Medicare Shared Savings Program (MSSP) Accountable Care Organization (ACO) is associated with a reduction in breast cancer screening and an increase in colorectal cancer

Updated on: March 27,2024

ACO enrollment ups appropriateness of CA screening

(HealthDay)—Enrollment in the Medicare Shared Savings Program (MSSP) Accountable Care Organization (ACO) is associated with a reduction in breast cancer screening and an increase in colorectal cancer

Updated on:March 27,2024

Seeking microscopic clues to beating deadly brain tumors

by Hackensack Meridian HealthH&E stained sections of patient glioblastoma samples. Higher magnifcation of representative regions are shown in the colored boxes. Histologic features include low (bl

Updated on: January 23,2024

Seeking microscopic clues to beating deadly brain tumors

by Hackensack Meridian HealthH&E stained sections of patient glioblastoma samples. Higher magnifcation of representative regions are shown in the colored boxes. Histologic features include low (bl

Updated on:January 23,2024

Software program that looks for the most effective drugs helps to personalize cancer treatments

byThe Spanish National Cancer Research CentreGraphical Abstract. Credit:Nucleic Acids Research(2023). DOI: 10.1093/nar/gkad412Precision medicine seeks to adapt treatments to the char

Updated on: January 16,2024

Software program that looks for the most effective drugs helps to personalize cancer treatments

byThe Spanish National Cancer Research CentreGraphical Abstract. Credit:Nucleic Acids Research(2023). DOI: 10.1093/nar/gkad412Precision medicine seeks to adapt treatments to the char

Updated on:January 16,2024

Simple test could lead to more personalized treatment of rare ovarian cancer

by University of New South WalesKaplan Meier curves of overall survival of ‘high’, ‘medium’ and ‘low’ tertiles of mRNA expression of THSB2 (left) and TAGLN (right) in MOC (n=185). Credit:Cl

Updated on: January 29,2024

Simple test could lead to more personalized treatment of rare ovarian cancer

by University of New South WalesKaplan Meier curves of overall survival of ‘high’, ‘medium’ and ‘low’ tertiles of mRNA expression of THSB2 (left) and TAGLN (right) in MOC (n=185). Credit:Cl

Updated on:January 29,2024

MTAP loss in metastatic breast cancer patients: Genomic landscape

by Impact Journals LLCMechanism of action of MTAP along with downstream effects from its loss. Abbreviations: MTAP: methylthioadenosine phosphorylase; MTR1P: 5-methylthioribose-1-phosphate; ODC: Ornit

Updated on: January 22,2024

MTAP loss in metastatic breast cancer patients: Genomic landscape

by Impact Journals LLCMechanism of action of MTAP along with downstream effects from its loss. Abbreviations: MTAP: methylthioadenosine phosphorylase; MTR1P: 5-methylthioribose-1-phosphate; ODC: Ornit

Updated on:January 22,2024

Lab-grown tumors predict treatment outcomes in landmark study

by Walter and Eliza Hall InstituteA 3D structure of an organoid formed from human bowel cancer cells. Blue marks the nucleus of the individual cell, green is a protein that sticks each cell toget

Updated on: March 05,2024

Lab-grown tumors predict treatment outcomes in landmark study

by Walter and Eliza Hall InstituteA 3D structure of an organoid formed from human bowel cancer cells. Blue marks the nucleus of the individual cell, green is a protein that sticks each cell toget

Updated on:March 05,2024