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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Researchers map the genome of testicular cancer

Researchers map the genome of testicular cancer

by Laura Oleniacz,UNC Lineberger Comprehensive Cancer CenterUNC Lineberger's Katherine Hoadley, PhD. Credit: UNC Lineberger Comprehensive Cancer CenterTesticular germ cell cancer, a disease

Researchers map the genome of testicular cancer

by Laura Oleniacz,UNC Lineberger Comprehensive Cancer CenterUNC Lineberger's Katherine Hoadley, PhD. Credit: UNC Lineberger Comprehensive Cancer CenterTesticular germ cell cancer, a disease
Soluble immune checkpoint factors in blood as potential biomarkers of therapeutic efficacy for ICI cancer immunotherapy

Soluble immune checkpoint factors in blood as potential biomarkers of therapeutic efficacy for ICI cancer immunotherapy

by Kindai UniversityThe concentration of soluble PD-L1m PD-1, CTLA4 in plasma were highly correlated with the expression of genes associated with exhaustion in the peripheral CD8+T cells. R valu

Soluble immune checkpoint factors in blood as potential biomarkers of therapeutic efficacy for ICI cancer immunotherapy

by Kindai UniversityThe concentration of soluble PD-L1m PD-1, CTLA4 in plasma were highly correlated with the expression of genes associated with exhaustion in the peripheral CD8+T cells. R valu
Researchers use AI to understand lung cancer cell vulnerabilities

Researchers use AI to understand lung cancer cell vulnerabilities

by University of MontanaMark Grimes, a researcher and University of Montana biology professor, uses AI to learn more about lung cancer vulnerabilities. Credit: University of Montana photo by Tomm

Researchers use AI to understand lung cancer cell vulnerabilities

by University of MontanaMark Grimes, a researcher and University of Montana biology professor, uses AI to learn more about lung cancer vulnerabilities. Credit: University of Montana photo by Tomm
Researchers find protein complex that regulates migration of neurons and neuroblastoma cancer cells

Researchers find protein complex that regulates migration of neurons and neuroblastoma cancer cells

by University of BarcelonaGraphical abstract. Credit:Cell(2022). DOI: 10.1016/j.cell.2022.09.025During brain development, neurons have to migrate long distances through complex enviro

Researchers find protein complex that regulates migration of neurons and neuroblastoma cancer cells

by University of BarcelonaGraphical abstract. Credit:Cell(2022). DOI: 10.1016/j.cell.2022.09.025During brain development, neurons have to migrate long distances through complex enviro
Therapeutic and diagnostic functions of one antibody for pancreatic cancer

Therapeutic and diagnostic functions of one antibody for pancreatic cancer

by Osaka UniversityFig.1: DKK1–CKAP4 signaling and application of the anti-CKAP4 antibody. DKK1 and CKAP4 are overexpressed in cancer cells and the PI3 kinase–AKT pathway is activated, promoting

Therapeutic and diagnostic functions of one antibody for pancreatic cancer

by Osaka UniversityFig.1: DKK1–CKAP4 signaling and application of the anti-CKAP4 antibody. DKK1 and CKAP4 are overexpressed in cancer cells and the PI3 kinase–AKT pathway is activated, promoting
A new approach to targeting tumors and tracking their spread

A new approach to targeting tumors and tracking their spread

by Massachusetts Institute of TechnologyKiller T cells surround a cancer cell. Credit: NIHThe spread of malignant cells from an original tumor to other parts of the body, known as metastasis, is

A new approach to targeting tumors and tracking their spread

by Massachusetts Institute of TechnologyKiller T cells surround a cancer cell. Credit: NIHThe spread of malignant cells from an original tumor to other parts of the body, known as metastasis, is
Study sheds light on the function of a long-mysterious PCSK9 mutation

Study sheds light on the function of a long-mysterious PCSK9 mutation

by American Society for Biochemistry and Molecular BiologyCredit: CC0 Public DomainHigh levels of low-density lipoproteins, parcels of lipids and protein that carry cholesterol, are a leading ris

Study sheds light on the function of a long-mysterious PCSK9 mutation

by American Society for Biochemistry and Molecular BiologyCredit: CC0 Public DomainHigh levels of low-density lipoproteins, parcels of lipids and protein that carry cholesterol, are a leading ris
Does being a caregiver affect older women's longevity?

Does being a caregiver affect older women's longevity?

by WileyCredit: Pixabay/CC0 Public DomainIn an analysis published in theJournal of the American Geriatrics Societythat included older US women, caregiving was associated with a lower

Does being a caregiver affect older women's longevity?

by WileyCredit: Pixabay/CC0 Public DomainIn an analysis published in theJournal of the American Geriatrics Societythat included older US women, caregiving was associated with a lower
New prostate cancer diagnostic pathway paves way for general screening

New prostate cancer diagnostic pathway paves way for general screening

bySwedish Research CouncilCredit: Pixabay/CC0 Public DomainIn screening for prostate cancer, the risk of overdiagnosis can be halved, a University of Gothenburg study shows. With the proposed di

New prostate cancer diagnostic pathway paves way for general screening

bySwedish Research CouncilCredit: Pixabay/CC0 Public DomainIn screening for prostate cancer, the risk of overdiagnosis can be halved, a University of Gothenburg study shows. With the proposed di
Researchers discover how to predict the efficacy of one of the most widely used drugs against breast cancer

Researchers discover how to predict the efficacy of one of the most widely used drugs against breast cancer

by The Spanish National Cancer Research CentreClinical trial tumor samples: the phosphoprofiles were independent of the study site and/or treatment arm.AClinical trial treatment and s

Researchers discover how to predict the efficacy of one of the most widely used drugs against breast cancer

by The Spanish National Cancer Research CentreClinical trial tumor samples: the phosphoprofiles were independent of the study site and/or treatment arm.AClinical trial treatment and s
Real-world data suggests stopping immunotherapy after two years is reasonable in patients with advanced lung cancer

Real-world data suggests stopping immunotherapy after two years is reasonable in patients with advanced lung cancer

byPerelman School of Medicine at the University of PennsylvaniaCredit: Pixabay/CC0 Public DomainOver the past decade, the approval of immune checkpoint inhibitors has revolutionized treatment fo

Real-world data suggests stopping immunotherapy after two years is reasonable in patients with advanced lung cancer

byPerelman School of Medicine at the University of PennsylvaniaCredit: Pixabay/CC0 Public DomainOver the past decade, the approval of immune checkpoint inhibitors has revolutionized treatment fo
Reversing chemotherapy resistance in pancreatic cancer

Reversing chemotherapy resistance in pancreatic cancer

byStanford UniversityCredit: CC0 Public DomainPancreatic cancer is a particularly aggressive and difficult-to-treat cancer, in part because it is often resistant to chemotherapy. Now, researcher

Reversing chemotherapy resistance in pancreatic cancer

byStanford UniversityCredit: CC0 Public DomainPancreatic cancer is a particularly aggressive and difficult-to-treat cancer, in part because it is often resistant to chemotherapy. Now, researcher