Researchers pinpoint why lymphoma patients may become resistant to specific therapy

by H. Lee Moffitt Cancer Center & Research InstituteHodgkin lymphoma, nodular lymphocyte predominant (high-power view) Credit: Gabriel Caponetti, MD./Wikipedia/CC BY-SA 3.0With more targeted

Updated on: June 01,2024

Researchers pinpoint why lymphoma patients may become resistant to specific therapy

by H. Lee Moffitt Cancer Center & Research InstituteHodgkin lymphoma, nodular lymphocyte predominant (high-power view) Credit: Gabriel Caponetti, MD./Wikipedia/CC BY-SA 3.0With more targeted

Updated on:June 01,2024

Assay to ID anticancer reagents targeting fructose-1,6-bisphosphate aldolase

by SLAS (Society for Laboratory Automation and Screening)ALDOA catalyzes the reversible aldol cleavage of fructose-1,6-bisphosphate (F-1,6-BP) into D-Glyceraldehyde-3-phosphate (GAP) and dihydroxyacet

Updated on: March 01,2024

Assay to ID anticancer reagents targeting fructose-1,6-bisphosphate aldolase

by SLAS (Society for Laboratory Automation and Screening)ALDOA catalyzes the reversible aldol cleavage of fructose-1,6-bisphosphate (F-1,6-BP) into D-Glyceraldehyde-3-phosphate (GAP) and dihydroxyacet

Updated on:March 01,2024

Reversing chemotherapy resistance in pancreatic cancer

byStanford UniversityCredit: CC0 Public DomainPancreatic cancer is a particularly aggressive and difficult-to-treat cancer, in part because it is often resistant to chemotherapy. Now, researcher

Updated on: July 05,2024

Reversing chemotherapy resistance in pancreatic cancer

byStanford UniversityCredit: CC0 Public DomainPancreatic cancer is a particularly aggressive and difficult-to-treat cancer, in part because it is often resistant to chemotherapy. Now, researcher

Updated on:July 05,2024

A new natural killer cell therapy product with promising anticancer effects

by DGIST (Daegu Gyeongbuk Institute of Science and Technology)Schematic diagram of the MBP technology in NK cells and expected role in the tumor site. (A) Schematic illustration of cytokine engineered

Updated on: February 03,2024

A new natural killer cell therapy product with promising anticancer effects

by DGIST (Daegu Gyeongbuk Institute of Science and Technology)Schematic diagram of the MBP technology in NK cells and expected role in the tumor site. (A) Schematic illustration of cytokine engineered

Updated on:February 03,2024

Breakdown of normal 3-D shape of DNA allows harmful interactions of genes in rare form of gastrointestinal stromal tumor

by Massachusetts General HospitalCredit: CC0 Public DomainMost cases of gastrointestinal stromal tumor (GIST), a type of soft-tissue cancer (sarcoma), are caused by mutations in genes that can be

Updated on: April 20,2024

Breakdown of normal 3-D shape of DNA allows harmful interactions of genes in rare form of gastrointestinal stromal tumor

by Massachusetts General HospitalCredit: CC0 Public DomainMost cases of gastrointestinal stromal tumor (GIST), a type of soft-tissue cancer (sarcoma), are caused by mutations in genes that can be

Updated on:April 20,2024

Blocking a protein to prevent injuries caused by radiation therapy

by Umea UniversityMahsa Fallah in lab. Credit: Johan GunséusIt is possible to prevent certain injuries that can occur in radiation therapy against cancer. By blocking the activity of a plasma pro

Updated on: April 01,2024

Blocking a protein to prevent injuries caused by radiation therapy

by Umea UniversityMahsa Fallah in lab. Credit: Johan GunséusIt is possible to prevent certain injuries that can occur in radiation therapy against cancer. By blocking the activity of a plasma pro

Updated on:April 01,2024

Some breast cancer patients with high responses to chemotherapy may not need surgery

by University of Texas M. D. Anderson Cancer CenterThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Credit:

Updated on: February 20,2024

Some breast cancer patients with high responses to chemotherapy may not need surgery

by University of Texas M. D. Anderson Cancer CenterThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Credit:

Updated on:February 20,2024

Drug-like molecules show early success in targeting breast cancer brain metastases

byDrexel UniversityComputational pipeline and predicted drug-like properties for the discovery of AD-2441 and its analogs. Credit:Frontiers in Pharmacology(2024). DOI: 10.3389/fphar.

Updated on: August 01,2024

Drug-like molecules show early success in targeting breast cancer brain metastases

byDrexel UniversityComputational pipeline and predicted drug-like properties for the discovery of AD-2441 and its analogs. Credit:Frontiers in Pharmacology(2024). DOI: 10.3389/fphar.

Updated on:August 01,2024

Tumor Metabolism Atlas offers a new way to discover cancer mechanisms

byWeill Cornell Medical CollegeCredit: AI-generated imageAn atlas that catalogs gene activity and the levels of small molecules called metabolites in tumor samples offers a new way of identifyin

Updated on: January 22,2024

Tumor Metabolism Atlas offers a new way to discover cancer mechanisms

byWeill Cornell Medical CollegeCredit: AI-generated imageAn atlas that catalogs gene activity and the levels of small molecules called metabolites in tumor samples offers a new way of identifyin

Updated on:January 22,2024

Minimal residual disease negativity predicts time to next treatment in multiple myeloma

by Elana GotkineFor patients with multiple myeloma (MM), minimal residual disease (MRD) negativity determined using next-generation sequencing (NGS) is predictive of longer time to next treatment (TTN

Updated on: January 22,2024

Minimal residual disease negativity predicts time to next treatment in multiple myeloma

by Elana GotkineFor patients with multiple myeloma (MM), minimal residual disease (MRD) negativity determined using next-generation sequencing (NGS) is predictive of longer time to next treatment (TTN

Updated on:January 22,2024

Study sends strong signal not to sequence immune checkpoint inhibitors in advanced kidney cancer

byDana-Farber Cancer InstituteCredit: Pixabay/CC0 Public DomainPatients with advanced kidney cancer are routinely given immune checkpoint inhibitors (ICIs) as first-line treatment. The CONTACT-0

Updated on: January 22,2024

Study sends strong signal not to sequence immune checkpoint inhibitors in advanced kidney cancer

byDana-Farber Cancer InstituteCredit: Pixabay/CC0 Public DomainPatients with advanced kidney cancer are routinely given immune checkpoint inhibitors (ICIs) as first-line treatment. The CONTACT-0

Updated on:January 22,2024

Study identifies novel epigenetic changes in pediatric brain cancer

by Melissa Rohman,Northwestern UniversityDNA methylation and transcriptomic landscape of recurrent ependymoma tumors. A Time-course summary of surgery, radio- and chemotherapy treatment and tumo

Updated on: February 23,2024

Study identifies novel epigenetic changes in pediatric brain cancer

by Melissa Rohman,Northwestern UniversityDNA methylation and transcriptomic landscape of recurrent ependymoma tumors. A Time-course summary of surgery, radio- and chemotherapy treatment and tumo

Updated on:February 23,2024