'RethiNKing' which immune cells are the best weapon against lung cancer

by Walter and Eliza Hall InstituteAustralian researchers have identified 'natural killer' cells as an important component of anti-tumour immunity to lung cancer.Image: sections of lung co

Updated on: April 01,2024

'RethiNKing' which immune cells are the best weapon against lung cancer

by Walter and Eliza Hall InstituteAustralian researchers have identified 'natural killer' cells as an important component of anti-tumour immunity to lung cancer.Image: sections of lung co

Updated on:April 01,2024

Exploring CAR T-cell therapy for aggressive follicular lymphoma

by Olivia Dimmer,Northwestern UniversityORR by best overall response per IRC assessment. Credit:Nature Medicine(2024). DOI: 10.1038/s41591-024-02986-9CAR T-cell therapy is an effecti

Updated on: August 01,2024

Exploring CAR T-cell therapy for aggressive follicular lymphoma

by Olivia Dimmer,Northwestern UniversityORR by best overall response per IRC assessment. Credit:Nature Medicine(2024). DOI: 10.1038/s41591-024-02986-9CAR T-cell therapy is an effecti

Updated on:August 01,2024

Rethinking the protein inhibitor approach to cancer therapy

byStony Brook UniversityTwo-step strategy for repeatable site-specific gene circuit integration.a, Network diagram of regulatory interactions and phenotypic impacts for native and ectopic

Updated on: January 22,2024

Rethinking the protein inhibitor approach to cancer therapy

byStony Brook UniversityTwo-step strategy for repeatable site-specific gene circuit integration.a, Network diagram of regulatory interactions and phenotypic impacts for native and ectopic

Updated on:January 22,2024

Formation of new blood vessels in tumors regulated by p38 protein

by Institute for Research in Biomedicine (IRB Barcelona)Structure of a blood vessel. Credit: Raquel Batlle, IRB BarcelonaA study performed at the Institute for Research in Biomedicine(IRB Barcelo

Updated on: April 07,2024

Formation of new blood vessels in tumors regulated by p38 protein

by Institute for Research in Biomedicine (IRB Barcelona)Structure of a blood vessel. Credit: Raquel Batlle, IRB BarcelonaA study performed at the Institute for Research in Biomedicine(IRB Barcelo

Updated on:April 07,2024

Editorial: GBP3-STING interaction in glioblastoma coordinates poor response to temozolomide

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainA new editorial paper was published inOncotarget, titled "GBP3-STING interaction in glioblastoma coordinates autophagy, anti-oxidative

Updated on: March 06,2024

Editorial: GBP3-STING interaction in glioblastoma coordinates poor response to temozolomide

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainA new editorial paper was published inOncotarget, titled "GBP3-STING interaction in glioblastoma coordinates autophagy, anti-oxidative

Updated on:March 06,2024

Researchers design 'prodrug' that targets cancer cells' big appetite for glutamine, leaving healthy cells unharmed

by Johns Hopkins University School of MedicineSchematic showing DRP-104's bio-activation to DON in tumor and bio-inactivation to an inert metabolite in GI tissues. Credit: Jennifer E. Fairman

Updated on: February 18,2024

Researchers design 'prodrug' that targets cancer cells' big appetite for glutamine, leaving healthy cells unharmed

by Johns Hopkins University School of MedicineSchematic showing DRP-104's bio-activation to DON in tumor and bio-inactivation to an inert metabolite in GI tissues. Credit: Jennifer E. Fairman

Updated on:February 18,2024

How immune cells detect and respond to mutations in cancer cells

byUniversity of California, Los AngelesScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDFor the first time, a r

Updated on: January 02,2024

How immune cells detect and respond to mutations in cancer cells

byUniversity of California, Los AngelesScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDFor the first time, a r

Updated on:January 02,2024

Preclinical characterization of therapeutic antibodies

by Rapamycin PressSchematic of experimental procedures for generation of novel anti-Sonic Hedgehog (Shh) candidate therapeutic antibodies directed at the carboxy (C)-terminal. (A) Two synthetic peptid

Updated on: March 12,2024

Preclinical characterization of therapeutic antibodies

by Rapamycin PressSchematic of experimental procedures for generation of novel anti-Sonic Hedgehog (Shh) candidate therapeutic antibodies directed at the carboxy (C)-terminal. (A) Two synthetic peptid

Updated on:March 12,2024

Study: 'GPS' seed devices effective in localizing breast tumors

by Tim Tedeschi,University of CincinnatiCredit: Pixabay/CC0 Public DomainUniversity of Cincinnati Cancer Center researchers found a seed device that acts as a GPS for surgeons to locate and remo

Updated on: March 06,2024

Study: 'GPS' seed devices effective in localizing breast tumors

by Tim Tedeschi,University of CincinnatiCredit: Pixabay/CC0 Public DomainUniversity of Cincinnati Cancer Center researchers found a seed device that acts as a GPS for surgeons to locate and remo

Updated on:March 06,2024

Study identifies how cancer-causing gene regulates genetic variation in prostate cancer

by Queen Mary, University of LondonGraphical abstract. Credit:Cell Reports(2022). DOI: 10.1016/j.celrep.2022.111404Researchers from Barts Cancer Institute (BCI) at Queen Mary Universi

Updated on: January 30,2024

Study identifies how cancer-causing gene regulates genetic variation in prostate cancer

by Queen Mary, University of LondonGraphical abstract. Credit:Cell Reports(2022). DOI: 10.1016/j.celrep.2022.111404Researchers from Barts Cancer Institute (BCI) at Queen Mary Universi

Updated on:January 30,2024

Researchers find tumor microbiome interactions may identify new approaches for pancreatic cancer treatment

by Rutgers UniversityCredit: Pixabay/CC0 Public DomainInvestigators from Rutgers Cancer Institute of New Jersey, the state's leading cancer center and only National Cancer Institute-Designate

Updated on: February 01,2024

Researchers find tumor microbiome interactions may identify new approaches for pancreatic cancer treatment

by Rutgers UniversityCredit: Pixabay/CC0 Public DomainInvestigators from Rutgers Cancer Institute of New Jersey, the state's leading cancer center and only National Cancer Institute-Designate

Updated on:February 01,2024

A new antibody capture method reveals G-quadruplex landscape and its regulation

by Impact Journals LLCA comparative analysis of G4 landscape in cultured cells usingAbCG4-ChIP. (A) A schematic of the conventional G4-ChIP highlighting the possibilities of false positive

Updated on: March 30,2024

A new antibody capture method reveals G-quadruplex landscape and its regulation

by Impact Journals LLCA comparative analysis of G4 landscape in cultured cells usingAbCG4-ChIP. (A) A schematic of the conventional G4-ChIP highlighting the possibilities of false positive

Updated on:March 30,2024