Rethinking the protein inhibitor approach to cancer therapy

byStony Brook UniversityTwo-step strategy for repeatable site-specific gene circuit integration.a, Network diagram of regulatory interactions and phenotypic impacts for native and ectopic

Updated on: January 22,2024

Rethinking the protein inhibitor approach to cancer therapy

byStony Brook UniversityTwo-step strategy for repeatable site-specific gene circuit integration.a, Network diagram of regulatory interactions and phenotypic impacts for native and ectopic

Updated on:January 22,2024

Novel T cell receptor therapy shows early anti-tumor activity

byUniversity of Texas M. D. Anderson Cancer CenterCredit: CC0 Public DomainAfamitresgene autoleucel (afami-cel; formerly ADP-A2M4), an adoptive T cell receptor (TCR) therapy targeting the MAGE-A

Updated on: January 15,2024

Novel T cell receptor therapy shows early anti-tumor activity

byUniversity of Texas M. D. Anderson Cancer CenterCredit: CC0 Public DomainAfamitresgene autoleucel (afami-cel; formerly ADP-A2M4), an adoptive T cell receptor (TCR) therapy targeting the MAGE-A

Updated on:January 15,2024

Dosing regimen for an old cancer drug shows new promise as an immunotherapy

by Bendta Schroeder,Massachusetts Institute of TechnologyA cancer cell (blue, center) can elude attack by immune cells (such as these T cells shown in green and red) by sequestering the mutated

Updated on: May 20,2024

Dosing regimen for an old cancer drug shows new promise as an immunotherapy

by Bendta Schroeder,Massachusetts Institute of TechnologyA cancer cell (blue, center) can elude attack by immune cells (such as these T cells shown in green and red) by sequestering the mutated

Updated on:May 20,2024

Some breast cancer treatments may limit effectiveness of weight loss medications

by The Endocrine SocietyCredit: Unsplash/CC0 Public DomainBreast cancer medications, called aromatase inhibitors, may lessen the effect of weight loss drugs, according to a new study being presen

Updated on: February 03,2024

Some breast cancer treatments may limit effectiveness of weight loss medications

by The Endocrine SocietyCredit: Unsplash/CC0 Public DomainBreast cancer medications, called aromatase inhibitors, may lessen the effect of weight loss drugs, according to a new study being presen

Updated on:February 03,2024

Simultaneous radiation and immunotherapy found to be beneficial for a subset of lung cancer patients

byUniversity of Chicago Medical CenterAneuploidy and TMB are synergistic predictors of survival following immunotherapy. Credit:Nature Genetics(2022). DOI: 10.1038/s41588-022-01235-4

Updated on: January 07,2024

Simultaneous radiation and immunotherapy found to be beneficial for a subset of lung cancer patients

byUniversity of Chicago Medical CenterAneuploidy and TMB are synergistic predictors of survival following immunotherapy. Credit:Nature Genetics(2022). DOI: 10.1038/s41588-022-01235-4

Updated on:January 07,2024

Researchers make major advance with cancer-killing antibody-drug conjugates

by Doug Bennett,University of FloridaCredit:Journal of Medicinal Chemistry(2023). DOI: 10.1021/acs.jmedchem.2c01771Building a new precision cancer treatment comes with no shortage of

Updated on: February 20,2024

Researchers make major advance with cancer-killing antibody-drug conjugates

by Doug Bennett,University of FloridaCredit:Journal of Medicinal Chemistry(2023). DOI: 10.1021/acs.jmedchem.2c01771Building a new precision cancer treatment comes with no shortage of

Updated on:February 20,2024

Study results show conjugate therapy produced remissions in one-third of patients with drug-resistant ovarian cancer

by Dana-Farber Cancer InstituteAntitumor activity of mirvetuximab soravtansine. (A) Maximum percentage change in target lesion size from baseline. Best response according to RECIST is indicated b

Updated on: January 30,2024

Study results show conjugate therapy produced remissions in one-third of patients with drug-resistant ovarian cancer

by Dana-Farber Cancer InstituteAntitumor activity of mirvetuximab soravtansine. (A) Maximum percentage change in target lesion size from baseline. Best response according to RECIST is indicated b

Updated on:January 30,2024

A simple intervention benefits cancer patients while saving hospitals money, study shows

by University of PittsburghCredit: Unsplash/CC0 Public DomainCancer patients who received specialized mental health support as part of their treatment plan were more likely to see improvements in

Updated on: March 20,2024

A simple intervention benefits cancer patients while saving hospitals money, study shows

by University of PittsburghCredit: Unsplash/CC0 Public DomainCancer patients who received specialized mental health support as part of their treatment plan were more likely to see improvements in

Updated on:March 20,2024

Engineered T cells may be harnessed to kill solid tumor cells

by Tel Aviv UniversityCredit: Tel Aviv UniversityThere is now a multitude of therapies to treat cancer, from chemotherapy and radiation to immunotherapy and small molecule inhibitors. Chemotherap

Updated on: March 01,2024

Engineered T cells may be harnessed to kill solid tumor cells

by Tel Aviv UniversityCredit: Tel Aviv UniversityThere is now a multitude of therapies to treat cancer, from chemotherapy and radiation to immunotherapy and small molecule inhibitors. Chemotherap

Updated on:March 01,2024

Study uncovers unknown interaction between leukemic cells and immune cells

by Karl Landsteiner University of Health SciencesAcute myelocytic leukemia (AML). Credit: Unsplash/CC0 Public DomainThe protein STAT3 helps the immune system to recognize leukemic cells. This interact

Updated on: July 17,2024

Study uncovers unknown interaction between leukemic cells and immune cells

by Karl Landsteiner University of Health SciencesAcute myelocytic leukemia (AML). Credit: Unsplash/CC0 Public DomainThe protein STAT3 helps the immune system to recognize leukemic cells. This interact

Updated on:July 17,2024

Researchers demonstrate RAS dimers are essential for cancer

by Cathy Frisinger,UT Southwestern Medical CenterRAS oncogenes work in pairs, known as "dimers." Credit: UT SouthwesternMutated RAS genes are some of the most common genetic drivers of

Updated on: June 01,2024

Researchers demonstrate RAS dimers are essential for cancer

by Cathy Frisinger,UT Southwestern Medical CenterRAS oncogenes work in pairs, known as "dimers." Credit: UT SouthwesternMutated RAS genes are some of the most common genetic drivers of

Updated on:June 01,2024

Researchers find new biomarker for breast cancer

by Austrian Science Fund (FWF)Mammograms showing a normal breast (left) and a breast with cancer (right). Credit: Public DomainWith the support of the FWF, an oncologist found a biomarker for bre

Updated on: March 01,2024

Researchers find new biomarker for breast cancer

by Austrian Science Fund (FWF)Mammograms showing a normal breast (left) and a breast with cancer (right). Credit: Public DomainWith the support of the FWF, an oncologist found a biomarker for bre

Updated on:March 01,2024