Researchers program cancer-fighting cells to resist exhaustion, attack solid tumors in mice

by Stanford University Medical CenterCredit: CC0 Public DomainA new approach to programing cancer-fighting immune cells called CAR-T cells can prolong their activity and increase their effectiven

Updated on: June 24,2024

Researchers program cancer-fighting cells to resist exhaustion, attack solid tumors in mice

by Stanford University Medical CenterCredit: CC0 Public DomainA new approach to programing cancer-fighting immune cells called CAR-T cells can prolong their activity and increase their effectiven

Updated on:June 24,2024

New anti-cancer 'degrader' targets protein essential to infant leukemia

byVan Andel Research InstituteDiscovery of a first-in-class, highly potent VHL-recruiting ENL PROTAC degrader, MS41. Credit:Science Advances(2024). DOI: 10.1126/sciadv.ado1432Scienti

Updated on: September 10,2024

New anti-cancer 'degrader' targets protein essential to infant leukemia

byVan Andel Research InstituteDiscovery of a first-in-class, highly potent VHL-recruiting ENL PROTAC degrader, MS41. Credit:Science Advances(2024). DOI: 10.1126/sciadv.ado1432Scienti

Updated on:September 10,2024

Study identifies how cancer-causing gene regulates genetic variation in prostate cancer

by Queen Mary, University of LondonGraphical abstract. Credit:Cell Reports(2022). DOI: 10.1016/j.celrep.2022.111404Researchers from Barts Cancer Institute (BCI) at Queen Mary Universi

Updated on: January 30,2024

Study identifies how cancer-causing gene regulates genetic variation in prostate cancer

by Queen Mary, University of LondonGraphical abstract. Credit:Cell Reports(2022). DOI: 10.1016/j.celrep.2022.111404Researchers from Barts Cancer Institute (BCI) at Queen Mary Universi

Updated on:January 30,2024

A cell culture system with temperature gradients to study optimal conditions for effective hyperthermia

by Beijing Institute of Technology Press Co.The temperature gradation on a metallic culture surface facilitates immediate and accurate control of cellular temperature stimuli, as well as simultaneous

Updated on: February 01,2024

A cell culture system with temperature gradients to study optimal conditions for effective hyperthermia

by Beijing Institute of Technology Press Co.The temperature gradation on a metallic culture surface facilitates immediate and accurate control of cellular temperature stimuli, as well as simultaneous

Updated on:February 01,2024

Researchers identify compounds that starve melanoma cancer cells of energy

by Oregon State UniversityMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0Researchers at Oregon State University a

Updated on: June 19,2024

Researchers identify compounds that starve melanoma cancer cells of energy

by Oregon State UniversityMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0Researchers at Oregon State University a

Updated on:June 19,2024

Leveraging allogeneic dendritic cells for neoantigen cancer vaccines

by Impact Journals LLCThe use of PDC*vac platform to develop NeoAg-based cancer vaccines. Credit: 2023 Hannani et al.A new research perspective was published inGenes & Canceron January

Updated on: December 28,2023

Leveraging allogeneic dendritic cells for neoantigen cancer vaccines

by Impact Journals LLCThe use of PDC*vac platform to develop NeoAg-based cancer vaccines. Credit: 2023 Hannani et al.A new research perspective was published inGenes & Canceron January

Updated on:December 28,2023

Predicting condensate formation by cancer-associated fusion oncoproteins

bySt. Jude Children's Research HospitalOverview of the fusion oncoprotein (FO) database (FOdb). Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-41655-2Many cancers ar

Updated on: January 07,2024

Predicting condensate formation by cancer-associated fusion oncoproteins

bySt. Jude Children's Research HospitalOverview of the fusion oncoprotein (FO) database (FOdb). Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-41655-2Many cancers ar

Updated on:January 07,2024

Researchers gain structural insights into the immune modulator Siglec-15 and its interaction with T cells

by CIC bioGUNEa Cartoon and surface representation of two views of the crystal structure of Siglec-15 in complex with anti-Siglec-15 5G12 Fab. 5G12 is composed of a heavy chain (HC) (in orange) and a

Updated on: February 18,2024

Researchers gain structural insights into the immune modulator Siglec-15 and its interaction with T cells

by CIC bioGUNEa Cartoon and surface representation of two views of the crystal structure of Siglec-15 in complex with anti-Siglec-15 5G12 Fab. 5G12 is composed of a heavy chain (HC) (in orange) and a

Updated on:February 18,2024

'Dead zone' within tumor promotes cancer spread, helped by a protein secreted by cancer cells

by Diana Mapes, Fred Hutchinson Cancer CenterFred Hutch's Ami Yamamoto, foreground, at work in the lab of Dr. Kevin Cheung (seen in background). Yamamoto's investigation of the necrotic core o

Updated on: February 18,2024

'Dead zone' within tumor promotes cancer spread, helped by a protein secreted by cancer cells

by Diana Mapes, Fred Hutchinson Cancer CenterFred Hutch's Ami Yamamoto, foreground, at work in the lab of Dr. Kevin Cheung (seen in background). Yamamoto's investigation of the necrotic core o

Updated on:February 18,2024

Having more babies lowers the risk of endometrial cancer, study finds

by Institute for Molecular BioscienceCredit: Unsplash/CC0 Public DomainUniversity of Queensland research has revealed that having more babies reduces a woman's risk of endometrial cancer.Dr. Gunn-

Updated on: January 23,2024

Having more babies lowers the risk of endometrial cancer, study finds

by Institute for Molecular BioscienceCredit: Unsplash/CC0 Public DomainUniversity of Queensland research has revealed that having more babies reduces a woman's risk of endometrial cancer.Dr. Gunn-

Updated on:January 23,2024

Promising new treatment for rare pregnancy cancer leads to remission in patients

by Maxine Myers,Imperial College LondonCredit: Imperial College LondonAn immunotherapy drug can be used to cure women of a rare type of cancer arising from pregnancy when existing treatments hav

Updated on: May 07,2024

Promising new treatment for rare pregnancy cancer leads to remission in patients

by Maxine Myers,Imperial College LondonCredit: Imperial College LondonAn immunotherapy drug can be used to cure women of a rare type of cancer arising from pregnancy when existing treatments hav

Updated on:May 07,2024

Ethical issues abound in adoption of AI in cancer care

by Lori SolomonThere may be ethical barriers to the adoption of artificial intelligence (AI) into cancer care, according to a studypublishedonline March 28 inJAMA Network Open.Andrew

Updated on: April 06,2024

Ethical issues abound in adoption of AI in cancer care

by Lori SolomonThere may be ethical barriers to the adoption of artificial intelligence (AI) into cancer care, according to a studypublishedonline March 28 inJAMA Network Open.Andrew

Updated on:April 06,2024