Investigating mechanisms of aggressive glioblastoma tumor growth

by Olivia Dimmer,Northwestern UniversitySchematic representation of the role of the LDHA–ERK–STAT3/YAP pathway in regulation of CCL2 and CCL7 in glioblastoma cells, which, in turn, promotes macr

Updated on: March 30,2024

Investigating mechanisms of aggressive glioblastoma tumor growth

by Olivia Dimmer,Northwestern UniversitySchematic representation of the role of the LDHA–ERK–STAT3/YAP pathway in regulation of CCL2 and CCL7 in glioblastoma cells, which, in turn, promotes macr

Updated on:March 30,2024

Study provides insight on targeted therapies for colorectal cancer metastasis

by Allison Perry,University of KentuckyKiller T cells surround a cancer cell. Credit: NIHA new study by University of Kentucky Markey Cancer Center researchers provides new insight on targeted t

Updated on: May 31,2024

Study provides insight on targeted therapies for colorectal cancer metastasis

by Allison Perry,University of KentuckyKiller T cells surround a cancer cell. Credit: NIHA new study by University of Kentucky Markey Cancer Center researchers provides new insight on targeted t

Updated on:May 31,2024

Examining the pesticides that may increase cancer risk in children

by Anna Novoselov,University of California, Los AngelesEstimated Odds Ratios and 95% Confidence Intervals from the Hierarchical Logistic Regression Model for all cases combined. Credit:Int

Updated on: February 03,2024

Examining the pesticides that may increase cancer risk in children

by Anna Novoselov,University of California, Los AngelesEstimated Odds Ratios and 95% Confidence Intervals from the Hierarchical Logistic Regression Model for all cases combined. Credit:Int

Updated on:February 03,2024

RNA splicing strategy corrects tumor suppressor gene in neuroendocrine cancers

byOsaka UniversityGraphical abstracts. REST_SSO directly modifies REST splicing and RE1 gene expression, whereas both REST_SSO and SRRM4_ASO exhibit antitumor effects in SCLC/NEPCa. Credit: 2024

Updated on: July 05,2024

RNA splicing strategy corrects tumor suppressor gene in neuroendocrine cancers

byOsaka UniversityGraphical abstracts. REST_SSO directly modifies REST splicing and RE1 gene expression, whereas both REST_SSO and SRRM4_ASO exhibit antitumor effects in SCLC/NEPCa. Credit: 2024

Updated on:July 05,2024

Neutrophil PAD4: How does it function in cancer beyond promoting NETosis?

by Impact Journals LLCMechanisms involved in regulation of tumor progression by neutrophil PAD4. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28369A new editorial paper titled "N

Updated on: April 09,2024

Neutrophil PAD4: How does it function in cancer beyond promoting NETosis?

by Impact Journals LLCMechanisms involved in regulation of tumor progression by neutrophil PAD4. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28369A new editorial paper titled "N

Updated on:April 09,2024

Team develops tools and techniques to explore cancer signals at the subcellular level

by Jerry Grillo,Georgia Institute of TechnologyGraphical abstract. Credit:iScience(2022). DOI: 10.1016/j.isci.2022.104980This year, about 240,000 people in the U.S. will discover the

Updated on: January 08,2024

Team develops tools and techniques to explore cancer signals at the subcellular level

by Jerry Grillo,Georgia Institute of TechnologyGraphical abstract. Credit:iScience(2022). DOI: 10.1016/j.isci.2022.104980This year, about 240,000 people in the U.S. will discover the

Updated on:January 08,2024

Autologous stem cell transplant may aid some with nodal PTCL

(HealthDay)—Autologous stem cell transplantation (ASCT) may be beneficial for some patients with nodal peripheral T-cell lymphoma (PTCL) in the first complete remission (CR1), according to a study pub

Updated on: April 01,2024

Autologous stem cell transplant may aid some with nodal PTCL

(HealthDay)—Autologous stem cell transplantation (ASCT) may be beneficial for some patients with nodal peripheral T-cell lymphoma (PTCL) in the first complete remission (CR1), according to a study pub

Updated on:April 01,2024

Genetic testing is important for women with breast cancer, expert says

by Rebecca Biason,University of TorontoCredit: Pixabay/CC0 Public DomainFor close to two decades Professor Kelly Metcalfe, a senior scientist at Women's College Research Institute and associ

Updated on: January 21,2024

Genetic testing is important for women with breast cancer, expert says

by Rebecca Biason,University of TorontoCredit: Pixabay/CC0 Public DomainFor close to two decades Professor Kelly Metcalfe, a senior scientist at Women's College Research Institute and associ

Updated on:January 21,2024

New machine-learning method may aid personalized cancer therapy

byJohns Hopkins University School of MedicineExperimental procedure. The procedure includes presentation training, immunogenicity transfer learning and independent evaluation on multiple dataset

Updated on: January 11,2024

New machine-learning method may aid personalized cancer therapy

byJohns Hopkins University School of MedicineExperimental procedure. The procedure includes presentation training, immunogenicity transfer learning and independent evaluation on multiple dataset

Updated on:January 11,2024

Repurposing FDA-approved drugs can help fight back breast cancer

by Baylor College of MedicineMicrograph showing a lymph node invaded by ductal breast carcinoma, with extension of the tumour beyond the lymph node. Credit: Nephron/WikipediaScreening Food and Dr

Updated on: April 07,2024

Repurposing FDA-approved drugs can help fight back breast cancer

by Baylor College of MedicineMicrograph showing a lymph node invaded by ductal breast carcinoma, with extension of the tumour beyond the lymph node. Credit: Nephron/WikipediaScreening Food and Dr

Updated on:April 07,2024

Scientists discover new survival strategy for oxygen-starved pancreatic cancer cells

by Monica May,Sanford Burnham Prebys Medical Discovery InstituteCredit: CC0 Public DomainOxygen is essential to life. When fast-growing tumor cells run out of oxygen, they quickly sprout new blo

Updated on: March 12,2024

Scientists discover new survival strategy for oxygen-starved pancreatic cancer cells

by Monica May,Sanford Burnham Prebys Medical Discovery InstituteCredit: CC0 Public DomainOxygen is essential to life. When fast-growing tumor cells run out of oxygen, they quickly sprout new blo

Updated on:March 12,2024

Some lymphomas become resistant to treatment. Gene discovery may offer path to overcome it.

by Will Cushman,University of Wisconsin-MadisonA confocal microscope image of lymphoma cells. It shows mitochondrial localization (red) around cell nuclei (blue). Credit: Lixin Rui, University o

Updated on: March 30,2024

Some lymphomas become resistant to treatment. Gene discovery may offer path to overcome it.

by Will Cushman,University of Wisconsin-MadisonA confocal microscope image of lymphoma cells. It shows mitochondrial localization (red) around cell nuclei (blue). Credit: Lixin Rui, University o

Updated on:March 30,2024