Why do cancer patients lose weight? Study points to elevated lactate levels

byNature Publishing GroupSchematic illustration depicting the signaling cascade downstream of lactate/GPR81 in promoting cancer cachexia. Credit:Nature Metabolism(2024). DOI: 10.1038

Updated on: March 30,2024

Why do cancer patients lose weight? Study points to elevated lactate levels

byNature Publishing GroupSchematic illustration depicting the signaling cascade downstream of lactate/GPR81 in promoting cancer cachexia. Credit:Nature Metabolism(2024). DOI: 10.1038

Updated on:March 30,2024

Discovery points to new approach to treating liver cancer

by Mary Martialay,Purdue UniversityReduced DDX5 protein levels in human HCCs associated with increased tumor grade and poor patient survival following sorafenib treatment.AImmunohist

Updated on: January 24,2024

Discovery points to new approach to treating liver cancer

by Mary Martialay,Purdue UniversityReduced DDX5 protein levels in human HCCs associated with increased tumor grade and poor patient survival following sorafenib treatment.AImmunohist

Updated on:January 24,2024

FDA approves first CAR T-cell therapy for adults with leukemia or lymphoma

by Lori SolomonThe U.S. Food and Drug Administration has approved Bristol Myers Squibb's Breyanzi (lisocabtagene maraleucel [liso-cel]) as the first CD19-directed chimeric antigen receptor (CAR) T

Updated on: March 30,2024

FDA approves first CAR T-cell therapy for adults with leukemia or lymphoma

by Lori SolomonThe U.S. Food and Drug Administration has approved Bristol Myers Squibb's Breyanzi (lisocabtagene maraleucel [liso-cel]) as the first CD19-directed chimeric antigen receptor (CAR) T

Updated on:March 30,2024

Enhanced treatment of liver carcinoma with a drug-eluting hydrogel

by Stewart Han, Terasaki Institute for Biomedical InnovationScientists from the Terasaki Institute for Biomedical Innovation (TIBI) have developed an injectable or catheter-administered hydrogel with

Updated on: January 02,2024

Enhanced treatment of liver carcinoma with a drug-eluting hydrogel

by Stewart Han, Terasaki Institute for Biomedical InnovationScientists from the Terasaki Institute for Biomedical Innovation (TIBI) have developed an injectable or catheter-administered hydrogel with

Updated on:January 02,2024

New potential cancer-driving genes identified, opening new paths for precision treatments

byInstitute of Cancer ResearchStudy design and number of samples per tumor type included in the analysis. Credit:Nature Genetics(2024). DOI: 10.1038/s41588-024-01785-9Researchers hav

Updated on: December 01,2024

New potential cancer-driving genes identified, opening new paths for precision treatments

byInstitute of Cancer ResearchStudy design and number of samples per tumor type included in the analysis. Credit:Nature Genetics(2024). DOI: 10.1038/s41588-024-01785-9Researchers hav

Updated on:December 01,2024

Evolving insights in blood-based liquid biopsies for prostate cancer interrogation

by Impact Journals LLCAnalysis of blood-based liquid biopsies in prostate cancer. Credit:Oncoscience(2023). DOI: 10.18632/oncoscience.592A new research perspective was published inOn

Updated on: January 02,2024

Evolving insights in blood-based liquid biopsies for prostate cancer interrogation

by Impact Journals LLCAnalysis of blood-based liquid biopsies in prostate cancer. Credit:Oncoscience(2023). DOI: 10.18632/oncoscience.592A new research perspective was published inOn

Updated on:January 02,2024

New CAR T-cell immunotherapy shows promising results for treating blood cancer patients

byKing's College LondonUCART19 cellular kinetics and correlation with clinical response. A, Graphical representation of UCART19 kinetic profile in PB of patients with B-ALL in the CALM study

Updated on: January 11,2024

New CAR T-cell immunotherapy shows promising results for treating blood cancer patients

byKing's College LondonUCART19 cellular kinetics and correlation with clinical response. A, Graphical representation of UCART19 kinetic profile in PB of patients with B-ALL in the CALM study

Updated on:January 11,2024

The tumor environment can affect breast cancer prognosis

byLund UniversityFlowchart of included and excluded patients and representative pictures of each CAV1 staining category in stroma and cytoplasm. Credit:Translational Oncology(2022).

Updated on: January 22,2024

The tumor environment can affect breast cancer prognosis

byLund UniversityFlowchart of included and excluded patients and representative pictures of each CAV1 staining category in stroma and cytoplasm. Credit:Translational Oncology(2022).

Updated on:January 22,2024

Study gives new insight into how cancer metastasizes to the brain

by The Wistar InstituteIFN signaling is activated in brain metastasis.a–cIFN signaling is activated in both human astrocytes and MDA231-BrM cells by coculture in vitro.N = 2 bio

Updated on: February 20,2024

Study gives new insight into how cancer metastasizes to the brain

by The Wistar InstituteIFN signaling is activated in brain metastasis.a–cIFN signaling is activated in both human astrocytes and MDA231-BrM cells by coculture in vitro.N = 2 bio

Updated on:February 20,2024

Softer tumors fuel more aggressive spread of triple-negative breast cancer, research shows

byGarvan Institute of Medical ResearchFluorescent image of cancer cells (cell nuclei in blue) stockpiling lipids in the form of lipid droplets (in red). The researchers showed these lipid drople

Updated on: April 28,2024

Softer tumors fuel more aggressive spread of triple-negative breast cancer, research shows

byGarvan Institute of Medical ResearchFluorescent image of cancer cells (cell nuclei in blue) stockpiling lipids in the form of lipid droplets (in red). The researchers showed these lipid drople

Updated on:April 28,2024

Amivantamab-lazertinib ups survival in EGFR-mutated advanced lung cancer

by Elana GotkineFor patients with EGFR-mutated advanced non-small cell lung cancer (NSCLC), amivantamab-lazertinib yields improved progression-free survival compared with osimertinib as first-line tre

Updated on: July 08,2024

Amivantamab-lazertinib ups survival in EGFR-mutated advanced lung cancer

by Elana GotkineFor patients with EGFR-mutated advanced non-small cell lung cancer (NSCLC), amivantamab-lazertinib yields improved progression-free survival compared with osimertinib as first-line tre

Updated on:July 08,2024

Ultrasound ovarian cancer screening improves survival

by University of KentuckyCredit: CC0 Public DomainA University of Kentucky study just published inObstetrics & Gynecologyshows that annual ultrasound screening of at-risk asymptom

Updated on: March 12,2024

Ultrasound ovarian cancer screening improves survival

by University of KentuckyCredit: CC0 Public DomainA University of Kentucky study just published inObstetrics & Gynecologyshows that annual ultrasound screening of at-risk asymptom

Updated on:March 12,2024