An elusive mechanism of wasting syndrome cachexia revealed

by Justin Jackson , Medical XpressOSM induces Eda2r expression in muscle and the depletion of OSMR protects from muscle wasting. a, Mouse primary myotubes were treated with recombinant TNFα, IL-6, LIF

Updated on: February 01,2024 16

An elusive mechanism of wasting syndrome cachexia revealed

by Justin Jackson , Medical XpressOSM induces Eda2r expression in muscle and the depletion of OSMR protects from muscle wasting. a, Mouse primary myotubes were treated with recombinant TNFα, IL-6, LIF

Updated on:February 01,2024 16

Percentage of breast cancer survivors in Canada doubles over past 15 years, study finds

by Jelena Damjanovic,University of Toronto(A) Distribution of breast cancer survivors by current (2022) age group. (B) Prevalence of net survivors of breast cancer within Canadian population by

Updated on: January 23,2024 12

Percentage of breast cancer survivors in Canada doubles over past 15 years, study finds

by Jelena Damjanovic,University of Toronto(A) Distribution of breast cancer survivors by current (2022) age group. (B) Prevalence of net survivors of breast cancer within Canadian population by

Updated on:January 23,2024 12

New study helps explain the anti-cancer properties of mannose sugar

bySanford Burnham Prebys Medical Discovery InstituteProposed model for the mechanism underlying anticancer activity of mannose in mannose phosphate isomerase knockout (MPI-KO) human cancer cells

Updated on: January 13,2024 16

New study helps explain the anti-cancer properties of mannose sugar

bySanford Burnham Prebys Medical Discovery InstituteProposed model for the mechanism underlying anticancer activity of mannose in mannose phosphate isomerase knockout (MPI-KO) human cancer cells

Updated on:January 13,2024 16

Identifying drug target candidates to treat pediatric rhabdomyosarcoma tumors

by Thamarasee Jeewandara , Medical XpressscRNAseq of RMS identifies heterogeneity recapitulating muscle developmental programs. (A) Experimental workflow. (B) UMAP plot of 48,859 RMS cells after regre

Updated on: January 02,2024 9

Identifying drug target candidates to treat pediatric rhabdomyosarcoma tumors

by Thamarasee Jeewandara , Medical XpressscRNAseq of RMS identifies heterogeneity recapitulating muscle developmental programs. (A) Experimental workflow. (B) UMAP plot of 48,859 RMS cells after regre

Updated on:January 02,2024 9

Designing an emergency stop switch for immunotherapies

by Ecole Polytechnique Federale de LausanneA mollecule allows for 'switching off' the therapy when a cancer patient's life is in danger. Credit: EPFLImmunotherapy, unlike chemotherapy

Updated on: March 09,2024 19

Designing an emergency stop switch for immunotherapies

by Ecole Polytechnique Federale de LausanneA mollecule allows for 'switching off' the therapy when a cancer patient's life is in danger. Credit: EPFLImmunotherapy, unlike chemotherapy

Updated on:March 09,2024 19

Exploring the role of RNA modification in normal hematopoiesis and acute myeloid leukemia pathogenesis

by Cactus CommunicationsThe review sheds light on the role of post-transcriptional RNA modifications in normal hematopoietic development and acute myeloid leukemia, and highlights novel therapeutic ta

Updated on: April 28,2024 0

Exploring the role of RNA modification in normal hematopoiesis and acute myeloid leukemia pathogenesis

by Cactus CommunicationsThe review sheds light on the role of post-transcriptional RNA modifications in normal hematopoietic development and acute myeloid leukemia, and highlights novel therapeutic ta

Updated on:April 28,2024 0

Novel blood test helps improve cancer treatments

by Kurt Bodenmüller,University of ZurichStudy scheme depicting the plasma sample collection schedule in the different patient groups. Credit:Radiotherapy and Oncology(2024). DOI: 10.

Updated on: July 08,2024 0

Novel blood test helps improve cancer treatments

by Kurt Bodenmüller,University of ZurichStudy scheme depicting the plasma sample collection schedule in the different patient groups. Credit:Radiotherapy and Oncology(2024). DOI: 10.

Updated on:July 08,2024 0

Blood test aids in predicting lung cancer mortality risk

byUniversity of Texas M. D. Anderson Cancer CenterCredit: CC0 Public DomainA blood-based test developed by researchers at The University of Texas MD Anderson Cancer Center can efficiently predic

Updated on: January 15,2024 10

Blood test aids in predicting lung cancer mortality risk

byUniversity of Texas M. D. Anderson Cancer CenterCredit: CC0 Public DomainA blood-based test developed by researchers at The University of Texas MD Anderson Cancer Center can efficiently predic

Updated on:January 15,2024 10

Targeted hope for metastatic cancer

by Paul Mayne,University of Western OntarioCancer cell during cell division. Credit: National Institutes of HealthA cancer diagnosis is tough enough to hear, but a diagnosis that cancer has spre

Updated on: April 01,2024 10

Targeted hope for metastatic cancer

by Paul Mayne,University of Western OntarioCancer cell during cell division. Credit: National Institutes of HealthA cancer diagnosis is tough enough to hear, but a diagnosis that cancer has spre

Updated on:April 01,2024 10

Innovations in cancer treatment through targeted bacterial vaccines

byScience China PressThe schematic illustrates how the nanovaccine induces robust anti-F. nucleatum immune responses that significantly improve the efficiency of chemotherapy and reduce cancer m

Updated on: September 10,2024 0

Innovations in cancer treatment through targeted bacterial vaccines

byScience China PressThe schematic illustrates how the nanovaccine induces robust anti-F. nucleatum immune responses that significantly improve the efficiency of chemotherapy and reduce cancer m

Updated on:September 10,2024 0

Delayed treatment effect predicting (DTEP) model found to enhance precision in immuno-oncology trial designs

by Science China PressAt the trial design stage, by inputting information on treatment stage, cancer type, and experimental and control arm regimens, investigators can utilize the nomogram or web

Updated on: March 30,2024 0

Delayed treatment effect predicting (DTEP) model found to enhance precision in immuno-oncology trial designs

by Science China PressAt the trial design stage, by inputting information on treatment stage, cancer type, and experimental and control arm regimens, investigators can utilize the nomogram or web

Updated on:March 30,2024 0

Investigating racial differences in multiple myeloma

by Melissa Rohman,Northwestern UniversityGenome-wide profiling of 5hmC from cfDNA derived from EA and AA patients with MM and its precursors. Genome-wide 5hmC was profiled in patient-derived pla

Updated on: January 22,2024 18

Investigating racial differences in multiple myeloma

by Melissa Rohman,Northwestern UniversityGenome-wide profiling of 5hmC from cfDNA derived from EA and AA patients with MM and its precursors. Genome-wide 5hmC was profiled in patient-derived pla

Updated on:January 22,2024 18