Researchers reveal role of PPDPF in development of mutant KRAS-driven pancreatic ductal adenocarcinoma

by Liu Jia,Chinese Academy of SciencesSchematic representation demonstrating the function of PPDPF in KRAS activation. Credit: Dr. XIE Dong's groupA recent study by Dr. Xie Dong's group

Updated on: February 20,2024 19

Researchers reveal role of PPDPF in development of mutant KRAS-driven pancreatic ductal adenocarcinoma

by Liu Jia,Chinese Academy of SciencesSchematic representation demonstrating the function of PPDPF in KRAS activation. Credit: Dr. XIE Dong's groupA recent study by Dr. Xie Dong's group

Updated on:February 20,2024 19

Mounjaro beats Ozempic for weight loss in early trial

by Robin FosterThe diabetes drug Mounjaro prompted more weight loss among overweight and obese adults than Ozempic did in a real-world setting, researchers report.Both Mounjaro (tirzepatide) and Ozemp

Updated on: March 06,2024 17

Mounjaro beats Ozempic for weight loss in early trial

by Robin FosterThe diabetes drug Mounjaro prompted more weight loss among overweight and obese adults than Ozempic did in a real-world setting, researchers report.Both Mounjaro (tirzepatide) and Ozemp

Updated on:March 06,2024 17

Study shows no mitotane needed for patients with low risk of recurrence of adrenocortical carcinoma

by Universitätsklinikum WürzburgAdrenocortical carcinoma is a malignant degeneration of one of the hormone glands, which sit in pairs as small caps on the kidney. Credit: Nuclear Medicine University H

Updated on: January 22,2024 10

Study shows no mitotane needed for patients with low risk of recurrence of adrenocortical carcinoma

by Universitätsklinikum WürzburgAdrenocortical carcinoma is a malignant degeneration of one of the hormone glands, which sit in pairs as small caps on the kidney. Credit: Nuclear Medicine University H

Updated on:January 22,2024 10

New immunotherapy holds promise for ovarian cancer

byKarolinska InstitutetIntermediate magnification micrograph of a low malignant potential (LMP) mucinous ovarian tumour. H&E stain. The micrograph shows: Simple mucinous epithelium (right) a

Updated on: January 12,2024 10

New immunotherapy holds promise for ovarian cancer

byKarolinska InstitutetIntermediate magnification micrograph of a low malignant potential (LMP) mucinous ovarian tumour. H&E stain. The micrograph shows: Simple mucinous epithelium (right) a

Updated on:January 12,2024 10

Identifying cancer genes' multiple personalities

byCold Spring Harbor LaboratoryAn up-close look at a mouse's liver; the cells with dark centers were turned cancerous using a new gene-editing strategy devised by Semir Beyaz's lab. Cred

Updated on: January 04,2024 15

Identifying cancer genes' multiple personalities

byCold Spring Harbor LaboratoryAn up-close look at a mouse's liver; the cells with dark centers were turned cancerous using a new gene-editing strategy devised by Semir Beyaz's lab. Cred

Updated on:January 04,2024 15

Researchers turn cancer cells into less harmful cell types

by University of BaselHigh-throughput drug screen reveals estrogen receptor α (ERα) induction in triple-negative breast cancer (TNBC) upon polo-like kinase 1 (PLK1) inhibition. A Schematic of the

Updated on: February 20,2024 16

Researchers turn cancer cells into less harmful cell types

by University of BaselHigh-throughput drug screen reveals estrogen receptor α (ERα) induction in triple-negative breast cancer (TNBC) upon polo-like kinase 1 (PLK1) inhibition. A Schematic of the

Updated on:February 20,2024 16

Genes with strong impact on menopause timing also link to cancer risk

byUniversity of ExeterCredit: Unsplash/CC0 Public DomainNew research has found four genes with some of the largest known effects on the timing of menopause discovered to date, providing new insi

Updated on: September 15,2024 0

Genes with strong impact on menopause timing also link to cancer risk

byUniversity of ExeterCredit: Unsplash/CC0 Public DomainNew research has found four genes with some of the largest known effects on the timing of menopause discovered to date, providing new insi

Updated on:September 15,2024 0

How 'paralyzed' immune cells can be reactivated against brain tumors

by German Cancer Research CenterGlioma of the left parietal lobe. CT scan with contrast enhancement. Credit: Mikhail Kalinin/CC BY-SA 3.0Brain tumor cells with a certain common mutation reprogram

Updated on: April 01,2024 11

How 'paralyzed' immune cells can be reactivated against brain tumors

by German Cancer Research CenterGlioma of the left parietal lobe. CT scan with contrast enhancement. Credit: Mikhail Kalinin/CC BY-SA 3.0Brain tumor cells with a certain common mutation reprogram

Updated on:April 01,2024 11

New computer platform helps match patients with cancer to trials of targeted therapy

byDana-Farber Cancer InstituteMatchMiner overview of data flow and modes of use. a) Data inputs from patients and trials are utilized by the MatchEngine to match patients to trials. b) Shown are

Updated on: January 12,2024 10

New computer platform helps match patients with cancer to trials of targeted therapy

byDana-Farber Cancer InstituteMatchMiner overview of data flow and modes of use. a) Data inputs from patients and trials are utilized by the MatchEngine to match patients to trials. b) Shown are

Updated on:January 12,2024 10

What is a mammogram, and why are they important?

by Laurel KellyCredit: Pixabay/CC0 Public DomainBreast cancer accounts for 1 in 3 of all new cancers diagnosed in women in the U.S. each year, according to the American Cancer Society. It's estima

Updated on: January 04,2024 9

What is a mammogram, and why are they important?

by Laurel KellyCredit: Pixabay/CC0 Public DomainBreast cancer accounts for 1 in 3 of all new cancers diagnosed in women in the U.S. each year, according to the American Cancer Society. It's estima

Updated on:January 04,2024 9

Pediatric brain cancer is rare. A doctor explains why some kids are more vulnerable than others

by Wendy RudermanCredit: Unsplash/CC0 Public DomainThe odds that a doctor will diagnose your child with pediatric cancer are slim, and the chances of a brain cancer diagnosis are even smaller.Each yea

Updated on: January 11,2024 15

Pediatric brain cancer is rare. A doctor explains why some kids are more vulnerable than others

by Wendy RudermanCredit: Unsplash/CC0 Public DomainThe odds that a doctor will diagnose your child with pediatric cancer are slim, and the chances of a brain cancer diagnosis are even smaller.Each yea

Updated on:January 11,2024 15

Researchers map the effects of all potential changes in key cancer gene

byThe Francis Crick InstituteFunction scores capture fitness effects mediated at both the transcript and protein 457 level. Credit: Megan Buckley et alResearchers at the Francis Crick Institute

Updated on: July 06,2024 0

Researchers map the effects of all potential changes in key cancer gene

byThe Francis Crick InstituteFunction scores capture fitness effects mediated at both the transcript and protein 457 level. Credit: Megan Buckley et alResearchers at the Francis Crick Institute

Updated on:July 06,2024 0