Patient-derived organoids in human cancer: A platform for fundamental research and precision medicine

by Sichuan International Medical Exchange and Promotion AssociationThe GBM organoids culture process and subsequent analysis are illustrated schematically. A rapid and dependable technique has been de

Updated on: March 30,2024

Patient-derived organoids in human cancer: A platform for fundamental research and precision medicine

by Sichuan International Medical Exchange and Promotion AssociationThe GBM organoids culture process and subsequent analysis are illustrated schematically. A rapid and dependable technique has been de

Updated on:March 30,2024

Research reveals why cancers stop responding to kinase-blocking drugs and come back stronger

by New York UniversityStructure of the FGFR kinase showing the locations of the gatekeeper residue in blue, hydrophobic spine in yellow, and ATP in cyan. Most drugs bind to the kinase in the same

Updated on: January 30,2024

Research reveals why cancers stop responding to kinase-blocking drugs and come back stronger

by New York UniversityStructure of the FGFR kinase showing the locations of the gatekeeper residue in blue, hydrophobic spine in yellow, and ATP in cyan. Most drugs bind to the kinase in the same

Updated on:January 30,2024

Drug suppresses spread of breast cancer caused by stem-like cells

by University of California - San DiegoA rare-stem like tumor cell, which plays a critical role in the spread of breast cancer, is identified with immunostaining for the β3 integrin subunit (blue

Updated on: March 12,2024

Drug suppresses spread of breast cancer caused by stem-like cells

by University of California - San DiegoA rare-stem like tumor cell, which plays a critical role in the spread of breast cancer, is identified with immunostaining for the β3 integrin subunit (blue

Updated on:March 12,2024

Investigational drug may combat brain tumors by targeting cancer cells' fat production

by Katie Marquedant,Massachusetts General HospitalCorrelation analysis between SCD expression and sensitivity to YTX-7739. (A) Immunoblot analysis (left) of SCD expression in YTX-7739-sensitive

Updated on: February 01,2024

Investigational drug may combat brain tumors by targeting cancer cells' fat production

by Katie Marquedant,Massachusetts General HospitalCorrelation analysis between SCD expression and sensitivity to YTX-7739. (A) Immunoblot analysis (left) of SCD expression in YTX-7739-sensitive

Updated on:February 01,2024

Researchers demonstrate technique for identifying single cancer cells in blood for the first time

byKeele UniversityBrightfield image of a cytospun sample containing PBMC and individual CALU-1 cancer cells. Credit:PLOS ONE(2023). DOI: 10.1371/journal.pone.0289824A pioneering stud

Updated on: March 30,2024

Researchers demonstrate technique for identifying single cancer cells in blood for the first time

byKeele UniversityBrightfield image of a cytospun sample containing PBMC and individual CALU-1 cancer cells. Credit:PLOS ONE(2023). DOI: 10.1371/journal.pone.0289824A pioneering stud

Updated on:March 30,2024

Polyploidy study reveals why some cancers are resistant to therapeutic drugs

byOsaka UniversityOverview of the study. (A) We created unique cells with double the usual number of chromosomes to investigate the relationship between polyploidy and DNA damage. (B) After trea

Updated on: November 09,2024

Polyploidy study reveals why some cancers are resistant to therapeutic drugs

byOsaka UniversityOverview of the study. (A) We created unique cells with double the usual number of chromosomes to investigate the relationship between polyploidy and DNA damage. (B) After trea

Updated on:November 09,2024

Researchers identify needs of rural-based physicians to optimize cancer survivorship care

by University of MissouriCredit: Unsplash/CC0 Public DomainThe vast majority of cancer survivors rely on primary care clinicians for follow-up treatments, especially in rural areas, according to

Updated on: February 03,2024

Researchers identify needs of rural-based physicians to optimize cancer survivorship care

by University of MissouriCredit: Unsplash/CC0 Public DomainThe vast majority of cancer survivors rely on primary care clinicians for follow-up treatments, especially in rural areas, according to

Updated on:February 03,2024

Researchers identify potential genetic variants linked to increased cancer risk in children with birth defects

by Children's Hospital of PhiladelphiaDemographic information of the cohort. aPhenotype information of the discovery cohort; bPhenotype information of the validation cohort; c&nbs

Updated on: February 01,2024

Researchers identify potential genetic variants linked to increased cancer risk in children with birth defects

by Children's Hospital of PhiladelphiaDemographic information of the cohort. aPhenotype information of the discovery cohort; bPhenotype information of the validation cohort; c&nbs

Updated on:February 01,2024

Early supper associated with lower risk of breast and prostate cancer

by Barcelona Institute for Global HealthEarly supper associated with breast and prostate cancer risk. Credit: ISGlobalHaving an early supper or leaving an interval of at least two hours before going t

Updated on: April 20,2024

Early supper associated with lower risk of breast and prostate cancer

by Barcelona Institute for Global HealthEarly supper associated with breast and prostate cancer risk. Credit: ISGlobalHaving an early supper or leaving an interval of at least two hours before going t

Updated on:April 20,2024

Protein linked to aggressive skin cancer

by Lund UniversityMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0Almost 300,000 people worldwide develop malignan

Updated on: May 07,2024

Protein linked to aggressive skin cancer

by Lund UniversityMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0Almost 300,000 people worldwide develop malignan

Updated on:May 07,2024

Cancer patients can quit smoking through lengthened medication time, counseling support

by Northwestern UniversityCredit: CC0 Public DomainQuitting smoking can significantly improve the effectiveness of cancer treatment, according to theU.S. Surgeon General,yet almost ha

Updated on: March 09,2024

Cancer patients can quit smoking through lengthened medication time, counseling support

by Northwestern UniversityCredit: CC0 Public DomainQuitting smoking can significantly improve the effectiveness of cancer treatment, according to theU.S. Surgeon General,yet almost ha

Updated on:March 09,2024

New PET tracer shows promise for uPAR-targeted therapy of neuroendocrine neoplasms

by Society of Nuclear Medicine and Molecular ImagingGraphical abstract. Credit:Journal of Nuclear Medicine(2022). DOI: 10.2967/jnumed.121.263177A novel PET radiotracer can accurately asses

Updated on: January 11,2024

New PET tracer shows promise for uPAR-targeted therapy of neuroendocrine neoplasms

by Society of Nuclear Medicine and Molecular ImagingGraphical abstract. Credit:Journal of Nuclear Medicine(2022). DOI: 10.2967/jnumed.121.263177A novel PET radiotracer can accurately asses

Updated on:January 11,2024