Resetting the epigenetic balance for cancer therapy

by Will Doss,Northwestern UniversityKiller T cells surround a cancer cell. Credit: NIHThough mutations in a gene called MLL3 are common across many types of cancers, their relationship to the de

Updated on: April 07,2024 12

Resetting the epigenetic balance for cancer therapy

by Will Doss,Northwestern UniversityKiller T cells surround a cancer cell. Credit: NIHThough mutations in a gene called MLL3 are common across many types of cancers, their relationship to the de

Updated on:April 07,2024 12

Amivantamab-lazertinib ups survival in EGFR-mutated advanced lung cancer

by Elana GotkineFor patients with EGFR-mutated advanced non-small cell lung cancer (NSCLC), amivantamab-lazertinib yields improved progression-free survival compared with osimertinib as first-line tre

Updated on: July 08,2024 0

Amivantamab-lazertinib ups survival in EGFR-mutated advanced lung cancer

by Elana GotkineFor patients with EGFR-mutated advanced non-small cell lung cancer (NSCLC), amivantamab-lazertinib yields improved progression-free survival compared with osimertinib as first-line tre

Updated on:July 08,2024 0

Bone cells suppress cancer metastases

by Thomas Jefferson UniversityCredit: CC0 Public DomainIn breast cancer, there are cases of women and men whose cancer returns in their bones 20-30 years after they were treated for their primary

Updated on: March 30,2024 10

Bone cells suppress cancer metastases

by Thomas Jefferson UniversityCredit: CC0 Public DomainIn breast cancer, there are cases of women and men whose cancer returns in their bones 20-30 years after they were treated for their primary

Updated on:March 30,2024 10

Editorial: GBP3-STING interaction in glioblastoma coordinates poor response to temozolomide

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainA new editorial paper was published inOncotarget, titled "GBP3-STING interaction in glioblastoma coordinates autophagy, anti-oxidative

Updated on: March 06,2024 13

Editorial: GBP3-STING interaction in glioblastoma coordinates poor response to temozolomide

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainA new editorial paper was published inOncotarget, titled "GBP3-STING interaction in glioblastoma coordinates autophagy, anti-oxidative

Updated on:March 06,2024 13

Researchers design 'prodrug' that targets cancer cells' big appetite for glutamine, leaving healthy cells unharmed

by Johns Hopkins University School of MedicineSchematic showing DRP-104's bio-activation to DON in tumor and bio-inactivation to an inert metabolite in GI tissues. Credit: Jennifer E. Fairman

Updated on: February 18,2024 14

Researchers design 'prodrug' that targets cancer cells' big appetite for glutamine, leaving healthy cells unharmed

by Johns Hopkins University School of MedicineSchematic showing DRP-104's bio-activation to DON in tumor and bio-inactivation to an inert metabolite in GI tissues. Credit: Jennifer E. Fairman

Updated on:February 18,2024 14

Editorial: Functional information offers individualized adaptive cancer therapies

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainAn editorial waspublishedin the journalOncoscienceon July 19, 2024, titled "Functional information offers individual

Updated on: September 07,2024 0

Editorial: Functional information offers individualized adaptive cancer therapies

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainAn editorial waspublishedin the journalOncoscienceon July 19, 2024, titled "Functional information offers individual

Updated on:September 07,2024 0

Clinical trial generates promising results for immunotherapy drug nivolumab in patients with advanced skin cancer

byWileyCredit: CC0 Public DomainNumerous studies have shown that drugs called immune checkpoint inhibitors can boost the immune system's response against various cancers. Now a phase II clin

Updated on: January 02,2024 9

Clinical trial generates promising results for immunotherapy drug nivolumab in patients with advanced skin cancer

byWileyCredit: CC0 Public DomainNumerous studies have shown that drugs called immune checkpoint inhibitors can boost the immune system's response against various cancers. Now a phase II clin

Updated on:January 02,2024 9

Researchers first to develop comprehensive models of 'seeds and soil' as a means to combat breast cancer metastasis

by Virginia Commonwealth UniversityFrom left to right: Mohammad Alzubi, Chuck Harrell, Ph.D., and Tia Turner. Credit: VCU Massey Cancer CenterScientists at VCU Massey Cancer Center have identifie

Updated on: June 06,2024 4

Researchers first to develop comprehensive models of 'seeds and soil' as a means to combat breast cancer metastasis

by Virginia Commonwealth UniversityFrom left to right: Mohammad Alzubi, Chuck Harrell, Ph.D., and Tia Turner. Credit: VCU Massey Cancer CenterScientists at VCU Massey Cancer Center have identifie

Updated on:June 06,2024 4

New class of drugs could treat ovarian cancer

by Mike Addelman,University of ManchesterIntermediate magnification micrograph of a low malignant potential (LMP) mucinous ovarian tumour. H&E stain. The micrograph shows: Simple mucinous ep

Updated on: May 17,2024 6

New class of drugs could treat ovarian cancer

by Mike Addelman,University of ManchesterIntermediate magnification micrograph of a low malignant potential (LMP) mucinous ovarian tumour. H&E stain. The micrograph shows: Simple mucinous ep

Updated on:May 17,2024 6

A new way to predict complications after larynx cancer surgery

by Nicole Fawcett,University of MichiganRebecca Hoesli, M.D., and Matthew Spector, M.D., evaluate an image from the study Credit: University of Michigan Rogel Cancer CenterA technique that illum

Updated on: May 17,2024 5

A new way to predict complications after larynx cancer surgery

by Nicole Fawcett,University of MichiganRebecca Hoesli, M.D., and Matthew Spector, M.D., evaluate an image from the study Credit: University of Michigan Rogel Cancer CenterA technique that illum

Updated on:May 17,2024 5

Hypofractioned post-prostatectomy radiotherapy new acceptable practice standard based on NRG Oncology trial findings

by NRG OncologyResults from the Phase III NRG Oncology NRG-GU003 clinical trial comparing hypofractioned post-prostatectomy radiotherapy (HYPORT) to conventionally fractioned post-prostatectomy radiot

Updated on: March 30,2024 0

Hypofractioned post-prostatectomy radiotherapy new acceptable practice standard based on NRG Oncology trial findings

by NRG OncologyResults from the Phase III NRG Oncology NRG-GU003 clinical trial comparing hypofractioned post-prostatectomy radiotherapy (HYPORT) to conventionally fractioned post-prostatectomy radiot

Updated on:March 30,2024 0

Researchers create machine learning model to calculate chemotherapy success in patients with osteosarcoma

by Johns Hopkins University School of MedicineA microscopic image of intramedullary osteosarcoma. Johns Hopkins researchers have trained a machine learning model use such images to calculate perc

Updated on: June 24,2024 6

Researchers create machine learning model to calculate chemotherapy success in patients with osteosarcoma

by Johns Hopkins University School of MedicineA microscopic image of intramedullary osteosarcoma. Johns Hopkins researchers have trained a machine learning model use such images to calculate perc

Updated on:June 24,2024 6