A potential therapeutic vaccine strategy for a subset of myeloproliferative neoplasms

by Ludwig Cancer ResearchCredit: CC0 Public DomainThe cells of a subset of myeloproliferative neoplasms (MPNs), slow-growing blood cancers, have frameshift mutations in their calreticulin (CALR)

Updated on: January 29,2024

A potential therapeutic vaccine strategy for a subset of myeloproliferative neoplasms

by Ludwig Cancer ResearchCredit: CC0 Public DomainThe cells of a subset of myeloproliferative neoplasms (MPNs), slow-growing blood cancers, have frameshift mutations in their calreticulin (CALR)

Updated on:January 29,2024

Discovering cancers of epigenetic origin without DNA mutation

byCNRSExample of a tumor obtained by reducing the expression levels of a Polycomb protein. On the left is an example of precursor tissue of the eye during normal development. On the right, a tum

Updated on: April 28,2024

Discovering cancers of epigenetic origin without DNA mutation

byCNRSExample of a tumor obtained by reducing the expression levels of a Polycomb protein. On the left is an example of precursor tissue of the eye during normal development. On the right, a tum

Updated on:April 28,2024

Arthritis linked to blood cancer mutations

by South Australian Health and Medical Research Institute (SAHMRI)Credit: Pixabay/CC0 Public DomainA team of Adelaide and U.S. researchers has discovered a link between a less common form of rheumatoi

Updated on: April 28,2024

Arthritis linked to blood cancer mutations

by South Australian Health and Medical Research Institute (SAHMRI)Credit: Pixabay/CC0 Public DomainA team of Adelaide and U.S. researchers has discovered a link between a less common form of rheumatoi

Updated on:April 28,2024

Researchers develop comprehensive new way to predict breast cancer risk

by Cancer Research UKThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image created in 2014 by Tom Misteli,

Updated on: June 08,2024

Researchers develop comprehensive new way to predict breast cancer risk

by Cancer Research UKThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image created in 2014 by Tom Misteli,

Updated on:June 08,2024

Study shows novel agent can overcome immune dysfunction in cancer

by Roswell Park Comprehensive Cancer CenterVSSP restores myeloid cell frequencies following leukopenia. C57BL/6 mice were injected with CY (200 mg/kg body weight, i.p.) and with two consecutive daily

Updated on: January 22,2024

Study shows novel agent can overcome immune dysfunction in cancer

by Roswell Park Comprehensive Cancer CenterVSSP restores myeloid cell frequencies following leukopenia. C57BL/6 mice were injected with CY (200 mg/kg body weight, i.p.) and with two consecutive daily

Updated on:January 22,2024

Two for the price of one: Mechanistic insights lead to drug repositioning

by University of TsukubaMolecular mechanism at a glance. SFN binds with SKP1 to sequester it in cytoplasm,resulting in the obstruction of SCFFBW7 598 complex formation. Oncoproteins including cyc

Updated on: May 23,2024

Two for the price of one: Mechanistic insights lead to drug repositioning

by University of TsukubaMolecular mechanism at a glance. SFN binds with SKP1 to sequester it in cytoplasm,resulting in the obstruction of SCFFBW7 598 complex formation. Oncoproteins including cyc

Updated on:May 23,2024

Researchers present advance in re-treatment with CAR T therapy

by Perelman School of Medicine at the University of PennsylvaniaHodgkin lymphoma, nodular lymphocyte predominant (high-power view) Credit: Gabriel Caponetti, MD./Wikipedia/CC BY-SA 3.0Researchers

Updated on: February 23,2024

Researchers present advance in re-treatment with CAR T therapy

by Perelman School of Medicine at the University of PennsylvaniaHodgkin lymphoma, nodular lymphocyte predominant (high-power view) Credit: Gabriel Caponetti, MD./Wikipedia/CC BY-SA 3.0Researchers

Updated on:February 23,2024

Most metastatic colorectal cancers have spread before diagnosis, researchers say

by Stanford University Medical CenterCancer—Histopathologic image of colonic carcinoid. Credit: Wikipedia/CC BY-SA 3.0Up to 80% of metastatic colorectal cancers are likely to have spread to dista

Updated on: June 06,2024

Most metastatic colorectal cancers have spread before diagnosis, researchers say

by Stanford University Medical CenterCancer—Histopathologic image of colonic carcinoid. Credit: Wikipedia/CC BY-SA 3.0Up to 80% of metastatic colorectal cancers are likely to have spread to dista

Updated on:June 06,2024

Technology holds personalised cancer vaccine breakthrough

by Kate Zischke,University of QueenslandThe attack of a tumour cell made by white blood cells of the patient (lymphocytes) generated by cancer vaccines. Credit: University of QueenslandUniversit

Updated on: March 06,2024

Technology holds personalised cancer vaccine breakthrough

by Kate Zischke,University of QueenslandThe attack of a tumour cell made by white blood cells of the patient (lymphocytes) generated by cancer vaccines. Credit: University of QueenslandUniversit

Updated on:March 06,2024

Neuronal molecule makes prostate cancer more aggressive

byThomas Jefferson UniversityCredit: Unsplash/CC0 Public DomainProstate cancer is the second most common cancer and the second leading cause of cancer death among American men. Now, researchers

Updated on: January 04,2024

Neuronal molecule makes prostate cancer more aggressive

byThomas Jefferson UniversityCredit: Unsplash/CC0 Public DomainProstate cancer is the second most common cancer and the second leading cause of cancer death among American men. Now, researchers

Updated on:January 04,2024

Study identifies new gene that drives colon cancer

by The Mount Sinai HospitalRecurrently dysregulated super-enhancers in CRC patients.aStudy overview. Figure adapted from SMART Servier Medical Art, reproduced with permission, license

Updated on: February 18,2024

Study identifies new gene that drives colon cancer

by The Mount Sinai HospitalRecurrently dysregulated super-enhancers in CRC patients.aStudy overview. Figure adapted from SMART Servier Medical Art, reproduced with permission, license

Updated on:February 18,2024

Over half of English patients with NSCLC in areas with low socio-economic levels do not receive anti-cancer therapies

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainNovel anti-cancer therapies were not accessible to more than half of the patients in England who were diagnose

Updated on: February 01,2024

Over half of English patients with NSCLC in areas with low socio-economic levels do not receive anti-cancer therapies

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainNovel anti-cancer therapies were not accessible to more than half of the patients in England who were diagnose

Updated on:February 01,2024