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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Experimental monoclonal antibodies can coax aggressive prostate and breast cancers into submission, finds research

Experimental monoclonal antibodies can coax aggressive prostate and breast cancers into submission, finds research

by Delthia Ricks , Medical XpressTherapeutic inhibition of VEGF binding to NRP2 activates anti-tumor immunity in a syngeneic model of prostate cancer that is resistant to aPD-L1 therapy. (A) Shown is

Experimental monoclonal antibodies can coax aggressive prostate and breast cancers into submission, finds research

by Delthia Ricks , Medical XpressTherapeutic inhibition of VEGF binding to NRP2 activates anti-tumor immunity in a syngeneic model of prostate cancer that is resistant to aPD-L1 therapy. (A) Shown is
Cis-regulatory sequences indicative of nasopharyngeal carcinoma risk identified

Cis-regulatory sequences indicative of nasopharyngeal carcinoma risk identified

by Justin Jackson , Medical XpressCredit:The American Journal of Human Genetics(2023). DOI: 10.1016/j.ajhg.2023.06.003Research led by the Sun Yat-sen University Cancer Center in China has

Cis-regulatory sequences indicative of nasopharyngeal carcinoma risk identified

by Justin Jackson , Medical XpressCredit:The American Journal of Human Genetics(2023). DOI: 10.1016/j.ajhg.2023.06.003Research led by the Sun Yat-sen University Cancer Center in China has
Tracing cancer back to birth uncovers promising biomarkers for prevention, targeted treatment of childhood leukemia

Tracing cancer back to birth uncovers promising biomarkers for prevention, targeted treatment of childhood leukemia

byMurdoch Children's Research InstituteDiscovery, validation and functional analysis of VTRNA2-1 methylation in association with pediatric pre-B ALL development. Credit:Molecular Cance

Tracing cancer back to birth uncovers promising biomarkers for prevention, targeted treatment of childhood leukemia

byMurdoch Children's Research InstituteDiscovery, validation and functional analysis of VTRNA2-1 methylation in association with pediatric pre-B ALL development. Credit:Molecular Cance
Epigenetic age and lung cancer risk in a prospective cohort study

Epigenetic age and lung cancer risk in a prospective cohort study

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainEpigenetic age, a robust marker of biological aging, has been associated with obesity, low-grade inflammation and metabolic diseases. However, fe

Epigenetic age and lung cancer risk in a prospective cohort study

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainEpigenetic age, a robust marker of biological aging, has been associated with obesity, low-grade inflammation and metabolic diseases. However, fe
Cellular power-up: Stem cells provide T cells a lifeline as cancer champions

Cellular power-up: Stem cells provide T cells a lifeline as cancer champions

by University of Los AndesExperimental workflow of MitoT to native and CAR engineered T cells. Credit:Journal of Translational Medicine(2024). DOI: 10.1186/s12967-024-05627-4In a pioneerin

Cellular power-up: Stem cells provide T cells a lifeline as cancer champions

by University of Los AndesExperimental workflow of MitoT to native and CAR engineered T cells. Credit:Journal of Translational Medicine(2024). DOI: 10.1186/s12967-024-05627-4In a pioneerin
Repurposing heart drugs to target cancer cells

Repurposing heart drugs to target cancer cells

by MRC London Institute of Medical SciencesCredit: CC0 Public DomainSenescence is a cellular stress response that results in the stable growth arrest of old and damaged cells. The past decade has reve

Repurposing heart drugs to target cancer cells

by MRC London Institute of Medical SciencesCredit: CC0 Public DomainSenescence is a cellular stress response that results in the stable growth arrest of old and damaged cells. The past decade has reve
A rare disease inspires a new way to attack cancer

A rare disease inspires a new way to attack cancer

by Nathan Collins,Stanford UniversityPostdoctoral fellow Ulla Gerling-Driessen, right, and her adviser, Carolyn Bertozzi, discuss their work on the NGLY1 molecule. Credit: L.A. CiceroSome of the

A rare disease inspires a new way to attack cancer

by Nathan Collins,Stanford UniversityPostdoctoral fellow Ulla Gerling-Driessen, right, and her adviser, Carolyn Bertozzi, discuss their work on the NGLY1 molecule. Credit: L.A. CiceroSome of the
Targeting refractory prostate cancer: A novel radiopharmaceutical hits the bullseye

Targeting refractory prostate cancer: A novel radiopharmaceutical hits the bullseye

by Osaka UniversityTargeted alpha therapy using an astatine-labeled PSMA ligand ([At-211]PSMA5). Credit: Tadashi Watabe (Osaka University)As the saying goes, when all you have is a hammer, everyt

Targeting refractory prostate cancer: A novel radiopharmaceutical hits the bullseye

by Osaka UniversityTargeted alpha therapy using an astatine-labeled PSMA ligand ([At-211]PSMA5). Credit: Tadashi Watabe (Osaka University)As the saying goes, when all you have is a hammer, everyt
Study shows novel agent can overcome immune dysfunction in cancer

Study shows novel agent can overcome immune dysfunction in cancer

by Roswell Park Comprehensive Cancer CenterVSSP restores myeloid cell frequencies following leukopenia. C57BL/6 mice were injected with CY (200 mg/kg body weight, i.p.) and with two consecutive daily

Study shows novel agent can overcome immune dysfunction in cancer

by Roswell Park Comprehensive Cancer CenterVSSP restores myeloid cell frequencies following leukopenia. C57BL/6 mice were injected with CY (200 mg/kg body weight, i.p.) and with two consecutive daily
A new therapeutic target for metastatic and resistant prostate cancers

A new therapeutic target for metastatic and resistant prostate cancers

by IDIBELL-Bellvitge Biomedical Research InstituteÁlvaro Aytés & Katia Ruggero. Credit: IDIBELLProstate Cancer researchers from the Bellvitge Biomedical Research Institute (IDIBELL), led by D

A new therapeutic target for metastatic and resistant prostate cancers

by IDIBELL-Bellvitge Biomedical Research InstituteÁlvaro Aytés & Katia Ruggero. Credit: IDIBELLProstate Cancer researchers from the Bellvitge Biomedical Research Institute (IDIBELL), led by D
Patient-derived organoids in human cancer: A platform for fundamental research and precision medicine

Patient-derived organoids in human cancer: A platform for fundamental research and precision medicine

by Sichuan International Medical Exchange and Promotion AssociationThe GBM organoids culture process and subsequent analysis are illustrated schematically. A rapid and dependable technique has been de

Patient-derived organoids in human cancer: A platform for fundamental research and precision medicine

by Sichuan International Medical Exchange and Promotion AssociationThe GBM organoids culture process and subsequent analysis are illustrated schematically. A rapid and dependable technique has been de
Doctors warn of New Zealand health tragedy after smoking ban scrapped

Doctors warn of New Zealand health tragedy after smoking ban scrapped

Credit: CC0 Public DomainDoctors blasted New Zealand's conservative government on Tuesday for revoking world-leading anti-smoking laws, warning that people will die over the act of "public he

Doctors warn of New Zealand health tragedy after smoking ban scrapped

Credit: CC0 Public DomainDoctors blasted New Zealand's conservative government on Tuesday for revoking world-leading anti-smoking laws, warning that people will die over the act of "public he