Cilta-cel found highly effective in first real-world study of patients with relapsed or refractory multiple myeloma

byAmerican Society of HematologyCredit: Pixabay/CC0 Public DomainIn the first study to report real-world outcomes from ciltacabtagene autoleucel (cilta-cel), a chimeric antigen receptor (CAR)-T

Updated on: November 09,2024 0

Cilta-cel found highly effective in first real-world study of patients with relapsed or refractory multiple myeloma

byAmerican Society of HematologyCredit: Pixabay/CC0 Public DomainIn the first study to report real-world outcomes from ciltacabtagene autoleucel (cilta-cel), a chimeric antigen receptor (CAR)-T

Updated on:November 09,2024 0

Promotion of cancer progression via extracellular vesicles

by Tokyo Medical and Dental UniversityUsually, blood vessels are stabilized, and their barrier function is maintained by the tight adhesion between vascular endothelial cells (①). When cancer cells me

Updated on: January 07,2024 15

Promotion of cancer progression via extracellular vesicles

by Tokyo Medical and Dental UniversityUsually, blood vessels are stabilized, and their barrier function is maintained by the tight adhesion between vascular endothelial cells (①). When cancer cells me

Updated on:January 07,2024 15

Drug resistance is a powerful menace in certain breast and ovarian cancers. Now scientists are figuring out why

by Delthia Ricks , Medical XpressCredit: Unsplash/CC0 Public DomainJust as bacteria, viruses and fungi develop strategies to outsmart antimicrobial medications, cancer cells can become resistant to ch

Updated on: February 18,2024 17

Drug resistance is a powerful menace in certain breast and ovarian cancers. Now scientists are figuring out why

by Delthia Ricks , Medical XpressCredit: Unsplash/CC0 Public DomainJust as bacteria, viruses and fungi develop strategies to outsmart antimicrobial medications, cancer cells can become resistant to ch

Updated on:February 18,2024 17

Primary pancreatic organoid tumor models for high-throughput phenotypic drug screening

by SLAS (Society for Laboratory Automation and Screening)A Z-stack image was obtained after staining nuclei with Hoechst using confocal microscopy at 5 micron intervals and then assembled using ImageJ

Updated on: May 09,2024 6

Primary pancreatic organoid tumor models for high-throughput phenotypic drug screening

by SLAS (Society for Laboratory Automation and Screening)A Z-stack image was obtained after staining nuclei with Hoechst using confocal microscopy at 5 micron intervals and then assembled using ImageJ

Updated on:May 09,2024 6

Drug that blocks blood vessel growth could treat rare sarcomas

by Institute of Cancer ResearchImage: Alveolar Soft Part Sarcoma. Credit: Michael Bonert.Licence: CC BY-SA 3.0An experimental targeted drug could treat a rare type of cancer usually affecti

Updated on: April 01,2024 16

Drug that blocks blood vessel growth could treat rare sarcomas

by Institute of Cancer ResearchImage: Alveolar Soft Part Sarcoma. Credit: Michael Bonert.Licence: CC BY-SA 3.0An experimental targeted drug could treat a rare type of cancer usually affecti

Updated on:April 01,2024 16

Second primary malignancy risk increased after cutaneous B-cell lymphoma

by Elana GotkinePatients with primary cutaneous B-cell lymphomas (PCBCLs) have an increased risk for second primary malignancies (SPMs), according to a studypublishedonline March 19 in the

Updated on: April 06,2024 0

Second primary malignancy risk increased after cutaneous B-cell lymphoma

by Elana GotkinePatients with primary cutaneous B-cell lymphomas (PCBCLs) have an increased risk for second primary malignancies (SPMs), according to a studypublishedonline March 19 in the

Updated on:April 06,2024 0

Fighting pancreatic cancer with computers and lasers

by Anthony King,Horizon: The EU Research & Innovation MagazinePancreatic cancer cells (blue) growing as a sphere encased in membranes (red). Credit: National Cancer InstituteFaster detection

Updated on: April 06,2024 0

Fighting pancreatic cancer with computers and lasers

by Anthony King,Horizon: The EU Research & Innovation MagazinePancreatic cancer cells (blue) growing as a sphere encased in membranes (red). Credit: National Cancer InstituteFaster detection

Updated on:April 06,2024 0

Researchers discover the Achilles' heel of an aggressive brain cancer

by University of HelsinkiGlioblastoma cells (red) are known to invade the brain (blue). Figure shows patient-derived glioblastoma in murine brain treated with saline (control). Credit: Laakkonen

Updated on: June 22,2024 6

Researchers discover the Achilles' heel of an aggressive brain cancer

by University of HelsinkiGlioblastoma cells (red) are known to invade the brain (blue). Figure shows patient-derived glioblastoma in murine brain treated with saline (control). Credit: Laakkonen

Updated on:June 22,2024 6

Active surveillance OK for non-muscle invasive bladder cancer

(HealthDay)—For patients with non-muscle invasive bladder cancer, active surveillance seems reasonable and cost-effective, according to a study published in the February issue ofThe Journal of U

Updated on: April 07,2024 11

Active surveillance OK for non-muscle invasive bladder cancer

(HealthDay)—For patients with non-muscle invasive bladder cancer, active surveillance seems reasonable and cost-effective, according to a study published in the February issue ofThe Journal of U

Updated on:April 07,2024 11

'Fingerprint database' could help scientists to identify new cancer culprits

by University of CambridgeCredit: CC0 Public DomainScientists in Cambridge and London have developed a catalogue of DNA mutation 'fingerprints' that could help doctors pinpoint the enviro

Updated on: April 10,2024 13

'Fingerprint database' could help scientists to identify new cancer culprits

by University of CambridgeCredit: CC0 Public DomainScientists in Cambridge and London have developed a catalogue of DNA mutation 'fingerprints' that could help doctors pinpoint the enviro

Updated on:April 10,2024 13

Knockout of CD5 on CAR T cells shown to boost anti-tumor efficacy

byPerelman School of Medicine at the University of PennsylvaniaCD5 KO enhances CAR T cell cytotoxicity. Credit:Science Immunology(2024). DOI: 10.1126/sciimmunol.adn6509The effectiven

Updated on: August 03,2024 0

Knockout of CD5 on CAR T cells shown to boost anti-tumor efficacy

byPerelman School of Medicine at the University of PennsylvaniaCD5 KO enhances CAR T cell cytotoxicity. Credit:Science Immunology(2024). DOI: 10.1126/sciimmunol.adn6509The effectiven

Updated on:August 03,2024 0

Immune system B-cells can help predict HER2-positive breast cancer treatment response

byUNC Lineberger Comprehensive Cancer CenterThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Credit: NCI Ce

Updated on: January 02,2024 9

Immune system B-cells can help predict HER2-positive breast cancer treatment response

byUNC Lineberger Comprehensive Cancer CenterThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Credit: NCI Ce

Updated on:January 02,2024 9