A new tool to study cell movement promises to advance cancer research

by University of MinnesotaOverview and validation of RAD-TGT function in CHO-K1 cells.aConceptual schematic of the force-induced rupture and readout of RAD-TGTs.bBrightfie

Updated on: February 18,2024

A new tool to study cell movement promises to advance cancer research

by University of MinnesotaOverview and validation of RAD-TGT function in CHO-K1 cells.aConceptual schematic of the force-induced rupture and readout of RAD-TGTs.bBrightfie

Updated on:February 18,2024

Novel therapeutic strategy against melanoma: Combined targeting of hedgehog signaling and BRD4

by Impact Journals LLCCombined targeting of SMO and BRD4 as a potential therapeutic strategy against melanoma. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28441A new editorial paper

Updated on: January 11,2024

Novel therapeutic strategy against melanoma: Combined targeting of hedgehog signaling and BRD4

by Impact Journals LLCCombined targeting of SMO and BRD4 as a potential therapeutic strategy against melanoma. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28441A new editorial paper

Updated on:January 11,2024

Tumor suppressor gene variants identified as cancer 'double whammy' for leukemia patients

by St. Jude Children's Research HospitalJun J. Yang, Ph.D., identified 22 high-risk germline variations associated with high-risk acute lymphoblastic leukemia that increases risk of relapse o

Updated on: April 07,2024

Tumor suppressor gene variants identified as cancer 'double whammy' for leukemia patients

by St. Jude Children's Research HospitalJun J. Yang, Ph.D., identified 22 high-risk germline variations associated with high-risk acute lymphoblastic leukemia that increases risk of relapse o

Updated on:April 07,2024

Patients coping with mesothelioma experienced higher levels of toxicity on CheckMate743 regimen than reported in trials

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainBased on results from the CheckMate743 trial, the dual regimen of ipilimumab and nivolumab is the standard of

Updated on: April 10,2024

Patients coping with mesothelioma experienced higher levels of toxicity on CheckMate743 regimen than reported in trials

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainBased on results from the CheckMate743 trial, the dual regimen of ipilimumab and nivolumab is the standard of

Updated on:April 10,2024

Researchers propose biomarkers to select breast cancer patients who could benefit from denosumab treatment

by The Spanish National Cancer Research CentreGraphical abstract. Credit:EMBO Molecular Medicine(2023). DOI: 10.15252/emmm.202216715The drug denosumab is currently used to treat osteo

Updated on: January 30,2024

Researchers propose biomarkers to select breast cancer patients who could benefit from denosumab treatment

by The Spanish National Cancer Research CentreGraphical abstract. Credit:EMBO Molecular Medicine(2023). DOI: 10.15252/emmm.202216715The drug denosumab is currently used to treat osteo

Updated on:January 30,2024

Research points to an immunotherapy to overcome resistant leukemia

by University of ZurichTP53 deficiency in AML leads to resistance against CAR T-cell-mediated killing that can be overcome by targeting the mevalonate and Wnt pathways. Credit:EMBO Molecula

Updated on: March 30,2024

Research points to an immunotherapy to overcome resistant leukemia

by University of ZurichTP53 deficiency in AML leads to resistance against CAR T-cell-mediated killing that can be overcome by targeting the mevalonate and Wnt pathways. Credit:EMBO Molecula

Updated on:March 30,2024

Multigene testing replacing BRCA tests for breast cancer risk, researcher says

by Stanford University Medical CenterThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image created in 2014

Updated on: June 24,2024

Multigene testing replacing BRCA tests for breast cancer risk, researcher says

by Stanford University Medical CenterThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image created in 2014

Updated on:June 24,2024

Researchers develop novel gold-nanocluster-based tumor radiodynamic therapy

by Zhang Nannan,Chinese Academy of SciencesGold-nanocluster-based radiodynamic therapy. Credit: IGDBRadiotherapy (RT) is a primary method of tumor treatment. However, in clinical practice, radio

Updated on: February 01,2024

Researchers develop novel gold-nanocluster-based tumor radiodynamic therapy

by Zhang Nannan,Chinese Academy of SciencesGold-nanocluster-based radiodynamic therapy. Credit: IGDBRadiotherapy (RT) is a primary method of tumor treatment. However, in clinical practice, radio

Updated on:February 01,2024

New study suggests way to predict outcomes with high accuracy prior to surgery for pancreatic cancer patients

by National Comprehensive Cancer NetworkPancreatic cancer cells (blue) growing as a sphere encased in membranes (red). Credit: National Cancer InstituteNew research in the September 2022 issue of&nbsp

Updated on: January 13,2024

New study suggests way to predict outcomes with high accuracy prior to surgery for pancreatic cancer patients

by National Comprehensive Cancer NetworkPancreatic cancer cells (blue) growing as a sphere encased in membranes (red). Credit: National Cancer InstituteNew research in the September 2022 issue of&nbsp

Updated on:January 13,2024

by Niigata UniversityCredit: Unsplash/CC0 Public DomainAn international team led by the Department of Neurosurgery, Niigata University, has identified a new gene called Schlafen11 (SLFN11) whose expre

Updated on: February 03,2024

by Niigata UniversityCredit: Unsplash/CC0 Public DomainAn international team led by the Department of Neurosurgery, Niigata University, has identified a new gene called Schlafen11 (SLFN11) whose expre

Updated on:February 03,2024

Researchers find effective drug combinations for glioblastoma in mice

by The Spanish National Cancer Research CentreTelomeres (red) in mouse embryonic fibroblasts; DNA damage (green) caused by ERK inhibition. ERK is an enzyme in the RAS pathway whose inhibition lea

Updated on: June 04,2024

Researchers find effective drug combinations for glioblastoma in mice

by The Spanish National Cancer Research CentreTelomeres (red) in mouse embryonic fibroblasts; DNA damage (green) caused by ERK inhibition. ERK is an enzyme in the RAS pathway whose inhibition lea

Updated on:June 04,2024

Virus linked to cancer takes over 'cellular mail' to alter tumor environment

by University of North Carolina at Chapel Hill School of MedicineRyan P. McNamara, PhD, is a postdoctoral research associate at UNC Lineberger. Credit: University of North Carolina at Chapel Hill

Updated on: May 07,2024

Virus linked to cancer takes over 'cellular mail' to alter tumor environment

by University of North Carolina at Chapel Hill School of MedicineRyan P. McNamara, PhD, is a postdoctoral research associate at UNC Lineberger. Credit: University of North Carolina at Chapel Hill

Updated on:May 07,2024