IBI322 Shows Early Antitumor Efficacy in PD-1/PD-L1–Resistant Classical Hodgkin Lymphoma

August 13, 2023Kristi RosaSingle-agent IBI322 elicited responses with favorable safety in patients with classical Hodgkin lymphoma that had become resistant to anti–PD-1/PD-L1 therapy, according to da

Updated on: October 12,2023 131

IBI322 Shows Early Antitumor Efficacy in PD-1/PD-L1–Resistant Classical Hodgkin Lymphoma

August 13, 2023Kristi RosaSingle-agent IBI322 elicited responses with favorable safety in patients with classical Hodgkin lymphoma that had become resistant to anti–PD-1/PD-L1 therapy, according to da

Updated on:October 12,2023 131

Uprooting cancer: Hydrogel rapidly reverts cancer cells back to cancer stem cells

A hydrogel developed at Hokkaido University successfully reverted cancer cells back to cancer stem cells within 24 hours in six different human cancer types. This could lead to the development of anti

Updated on: November 02,2023 10

Uprooting cancer: Hydrogel rapidly reverts cancer cells back to cancer stem cells

A hydrogel developed at Hokkaido University successfully reverted cancer cells back to cancer stem cells within 24 hours in six different human cancer types. This could lead to the development of anti

Updated on:November 02,2023 10

Study finds less-aggressive chemotherapy after initial treatment for metastatic colorectal cancer to be more beneficial

byMayo ClinicCancer—Histopathologic image of colonic carcinoid. Credit: Wikipedia/CC BY-SA 3.0A Mayo Clinic study involving 5,540 patients with metastatic colorectal cancer finds that maintenanc

Updated on: December 22,2023 24

Study finds less-aggressive chemotherapy after initial treatment for metastatic colorectal cancer to be more beneficial

byMayo ClinicCancer—Histopathologic image of colonic carcinoid. Credit: Wikipedia/CC BY-SA 3.0A Mayo Clinic study involving 5,540 patients with metastatic colorectal cancer finds that maintenanc

Updated on:December 22,2023 24

Healthy diets linked to better outcomes in colorectal cancer

byAmerican Cancer SocietyCredit: CC0 Public DomainColorectal cancer patients who followed healthy diets had a lower risk of death from colorectal cancer and all causes, even those who improved t

Updated on: December 18,2023 13

Healthy diets linked to better outcomes in colorectal cancer

byAmerican Cancer SocietyCredit: CC0 Public DomainColorectal cancer patients who followed healthy diets had a lower risk of death from colorectal cancer and all causes, even those who improved t

Updated on:December 18,2023 13

Novel therapeutic targets discovered for triple-negative breast cancer

by Melissa Rohman,Northwestern UniversityThe signature of TRIM21low/CD73highis associated with unfavorable immune response. (A) Proteomic data from CPTAC identified that the expression of

Updated on: December 21,2023 13

Novel therapeutic targets discovered for triple-negative breast cancer

by Melissa Rohman,Northwestern UniversityThe signature of TRIM21low/CD73highis associated with unfavorable immune response. (A) Proteomic data from CPTAC identified that the expression of

Updated on:December 21,2023 13

Comparing DNA changes in blood stem cells and leukemia cells could help pick out children with high-risk AML

Credit: Unsplash/CC0 Public DomainIn some children with acute myeloid leukemia, cancer cells have as many DNA changes as healthy blood stem cells. Researchers were surprised to find these children hav

Updated on: November 02,2023 10

Comparing DNA changes in blood stem cells and leukemia cells could help pick out children with high-risk AML

Credit: Unsplash/CC0 Public DomainIn some children with acute myeloid leukemia, cancer cells have as many DNA changes as healthy blood stem cells. Researchers were surprised to find these children hav

Updated on:November 02,2023 10

U.S. incidence of thyroid cancer plateaued in 2009

(HealthDay)—From 2009 to 2016, the incidence of thyroid cancer reached a plateau and possibly started to decline, according to a research letter published in the Dec. 24/31 issue of theJournal o

Updated on: December 20,2023 15

U.S. incidence of thyroid cancer plateaued in 2009

(HealthDay)—From 2009 to 2016, the incidence of thyroid cancer reached a plateau and possibly started to decline, according to a research letter published in the Dec. 24/31 issue of theJournal o

Updated on:December 20,2023 15

Radiotherapy for ductal in situ carcinoma ups mortality risk in invasive second breast cancer

(HealthDay)—For women with primary ductal carcinoma in situ (DCIS), use of radiotherapy (RT) is associated with increased rates of breast cancer-specific mortality for those women who subsequently dev

Updated on: December 22,2023 19

Radiotherapy for ductal in situ carcinoma ups mortality risk in invasive second breast cancer

(HealthDay)—For women with primary ductal carcinoma in situ (DCIS), use of radiotherapy (RT) is associated with increased rates of breast cancer-specific mortality for those women who subsequently dev

Updated on:December 22,2023 19

ATR inhibition using gartisertib in patient-derived glioblastoma cell lines

by Impact Journals LLCUpregulated genes and pathways enriched in glioblastoma cell lines treated with gartisertib combined with TMZ+RT. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28

Updated on: May 11,2024 3

ATR inhibition using gartisertib in patient-derived glioblastoma cell lines

by Impact Journals LLCUpregulated genes and pathways enriched in glioblastoma cell lines treated with gartisertib combined with TMZ+RT. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28

Updated on:May 11,2024 3

FAM3C encapsulated in circulating tumor-derived extracellular vesicles promotes distant growth in lung cancers

byNational University of SingaporeTumor-derived EVs containing FAM3C trigger aggressiveness of lung carcinoma cells in vivo. (A) Tail vein injection of A549 lung carcinoma cells in mouse model a

Updated on: December 19,2023 6

FAM3C encapsulated in circulating tumor-derived extracellular vesicles promotes distant growth in lung cancers

byNational University of SingaporeTumor-derived EVs containing FAM3C trigger aggressiveness of lung carcinoma cells in vivo. (A) Tail vein injection of A549 lung carcinoma cells in mouse model a

Updated on:December 19,2023 6

Optimizing Lung Cancer Treatment: The Role of CPT1A in Ferroptosis and Immunotherapy Enhancement

Updated on: June 15,2024 0

Optimizing Lung Cancer Treatment: The Role of CPT1A in Ferroptosis and Immunotherapy Enhancement

Updated on:June 15,2024 0

Seeking leukemia's Achilles heel

byAmerican Society for Biochemistry and Molecular BiologyGraphical abstract. Credit:Molecular & Cellular Proteomics(2023). DOI: 10.1016/j.mcpro.2023.100503A team of researchers h

Updated on: December 17,2023 10

Seeking leukemia's Achilles heel

byAmerican Society for Biochemistry and Molecular BiologyGraphical abstract. Credit:Molecular & Cellular Proteomics(2023). DOI: 10.1016/j.mcpro.2023.100503A team of researchers h

Updated on:December 17,2023 10