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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Pinpointing the prevalence of mismatch repair (MMR)-deficient rectal adenocarcinomas

Pinpointing the prevalence of mismatch repair (MMR)-deficient rectal adenocarcinomas

byBrigham and Women's HospitalCredit: Pixabay/CC0 Public DomainA widely-circulated clinical trial published earlier this year in theNew England Journal of Medicine (NEJM)describe

Pinpointing the prevalence of mismatch repair (MMR)-deficient rectal adenocarcinomas

byBrigham and Women's HospitalCredit: Pixabay/CC0 Public DomainA widely-circulated clinical trial published earlier this year in theNew England Journal of Medicine (NEJM)describe
Unique gene signature could help predict response to chemotherapy

Unique gene signature could help predict response to chemotherapy

byThe Francis Crick InstituteIn vitro anticancer drug screen. a Volcano plots showing differences in IC50 values between RAS high and low CCLE cell lines. Drugs with enriched target annotations

Unique gene signature could help predict response to chemotherapy

byThe Francis Crick InstituteIn vitro anticancer drug screen. a Volcano plots showing differences in IC50 values between RAS high and low CCLE cell lines. Drugs with enriched target annotations
Estrogen may facilitate the growth of liver metastases in non-sex-specific cancers

Estrogen may facilitate the growth of liver metastases in non-sex-specific cancers

byMcGill UniversityCancer cell during cell division. Credit: National Institutes of HealthIt is known that the tumor microenvironment plays an important role in the progression of cancer. But co

Estrogen may facilitate the growth of liver metastases in non-sex-specific cancers

byMcGill UniversityCancer cell during cell division. Credit: National Institutes of HealthIt is known that the tumor microenvironment plays an important role in the progression of cancer. But co
CAR T cell therapy for T cell lymphoma shows promise in phase I trial

CAR T cell therapy for T cell lymphoma shows promise in phase I trial

by Molly Chiu,Baylor College of MedicineCredit: Pixabay/CC0 Public DomainResearchers at the Center for Cell and Gene Therapy at Baylor College of Medicine, Texas Children's Hospital, and Hou

CAR T cell therapy for T cell lymphoma shows promise in phase I trial

by Molly Chiu,Baylor College of MedicineCredit: Pixabay/CC0 Public DomainResearchers at the Center for Cell and Gene Therapy at Baylor College of Medicine, Texas Children's Hospital, and Hou
Study finds early switch to oral antibiotic therapy for S. aureus bloodstream infections is safe, effective

Study finds early switch to oral antibiotic therapy for S. aureus bloodstream infections is safe, effective

by University of CologneCredit: Unsplash/CC0 Public DomainA new study shows efficacy and safety of oral antibiotic therapy, in the form of pills, for Staphylococcus aureus bloodstream infections.

Study finds early switch to oral antibiotic therapy for S. aureus bloodstream infections is safe, effective

by University of CologneCredit: Unsplash/CC0 Public DomainA new study shows efficacy and safety of oral antibiotic therapy, in the form of pills, for Staphylococcus aureus bloodstream infections.
New study reveals how epithelial cells in the body naturally eliminate 'precancerous' ones

New study reveals how epithelial cells in the body naturally eliminate 'precancerous' ones

by Waseda UniversityWaseda University researchers identify the underlying mechanism behind the extrusion of precancerous cells by epithelial cells, a mechanism that prevents the formation of canc

New study reveals how epithelial cells in the body naturally eliminate 'precancerous' ones

by Waseda UniversityWaseda University researchers identify the underlying mechanism behind the extrusion of precancerous cells by epithelial cells, a mechanism that prevents the formation of canc
Cancer cells hijack enhancer DNA to grow faster, study finds

Cancer cells hijack enhancer DNA to grow faster, study finds

University of Toronto (U of T) researchers have found that cancer cells can enhance tumor growth by hijacking enhancer DNA normally used when tissues and organs are formed. The mechanism, called enhan

Cancer cells hijack enhancer DNA to grow faster, study finds

University of Toronto (U of T) researchers have found that cancer cells can enhance tumor growth by hijacking enhancer DNA normally used when tissues and organs are formed. The mechanism, called enhan
More breast cancer patients can choose smaller surgery

More breast cancer patients can choose smaller surgery

by Carla K. JohnsonA technician displays images of a mammogram scan on a computer screen at a hospital in Odessa, Texas, on Wednesday, Oct. 20, 2021. A study discussed Friday, Dec. 9, 2022, at the San

More breast cancer patients can choose smaller surgery

by Carla K. JohnsonA technician displays images of a mammogram scan on a computer screen at a hospital in Odessa, Texas, on Wednesday, Oct. 20, 2021. A study discussed Friday, Dec. 9, 2022, at the San
Trial shows timing matters when adding immunotherapy to chemoradiation for limited-stage small cell lung cancer

Trial shows timing matters when adding immunotherapy to chemoradiation for limited-stage small cell lung cancer

byAmerican Society for Radiation OncologyCredit: Pixabay/CC0 Public DomainPeople with limited-stage small cell lung cancer may benefit from adding immunotherapy to chemoradiation, but not if bot

Trial shows timing matters when adding immunotherapy to chemoradiation for limited-stage small cell lung cancer

byAmerican Society for Radiation OncologyCredit: Pixabay/CC0 Public DomainPeople with limited-stage small cell lung cancer may benefit from adding immunotherapy to chemoradiation, but not if bot
Cancer mortality continues steady decline, driven by progress against lung cancer

Cancer mortality continues steady decline, driven by progress against lung cancer

byAmerican Cancer SocietyTrends in Overall Cancer Mortality Rates by Sex, United States, 1930 to 2017. Rates are age adjusted to the 2000 US standard population Credit: American Cancer SocietyTh

Cancer mortality continues steady decline, driven by progress against lung cancer

byAmerican Cancer SocietyTrends in Overall Cancer Mortality Rates by Sex, United States, 1930 to 2017. Rates are age adjusted to the 2000 US standard population Credit: American Cancer SocietyTh
Overexpressed Cyclin D1 and CDK4 proteins are responsible for the resistance to CDK4/6 inhibitor in some breast cancer

Overexpressed Cyclin D1 and CDK4 proteins are responsible for the resistance to CDK4/6 inhibitor in some breast cancer

byScience China PressThe CDK4/6 inhibitors-resistant breast cancer cells expressed more Cyclin D1 and CDK4 proteins than the parental cells (Upper left). PI3K pathway was hyper-activated in the

Overexpressed Cyclin D1 and CDK4 proteins are responsible for the resistance to CDK4/6 inhibitor in some breast cancer

byScience China PressThe CDK4/6 inhibitors-resistant breast cancer cells expressed more Cyclin D1 and CDK4 proteins than the parental cells (Upper left). PI3K pathway was hyper-activated in the