New screening tool to explore mechanisms behind cancer, autoimmunity and neurodegeneration

by Jelena Pupavac,Wellcome Trust Sanger InstituteA single-cell base editor screen tiling acrossJAK1is improved by coupling genotype with transcriptome.aUMAP of LoF and no

Updated on: April 23,2024 0

New screening tool to explore mechanisms behind cancer, autoimmunity and neurodegeneration

by Jelena Pupavac,Wellcome Trust Sanger InstituteA single-cell base editor screen tiling acrossJAK1is improved by coupling genotype with transcriptome.aUMAP of LoF and no

Updated on:April 23,2024 0

An accurate integrated imaging and projection system for oral cancer diagnosis

by SPIEImaging workflow of the ABGS. Step 1: widefield images are acquired using the camera and projector. Step 2: a cancer risk map is generated and projected onto the oral cavity. Step 3: multi

Updated on: February 18,2024 11

An accurate integrated imaging and projection system for oral cancer diagnosis

by SPIEImaging workflow of the ABGS. Step 1: widefield images are acquired using the camera and projector. Step 2: a cancer risk map is generated and projected onto the oral cavity. Step 3: multi

Updated on:February 18,2024 11

Epigenetic mechanism associated with clinical outcome and therapeutic vulnerability in liver cancer

by Josep Carreras Leukaemia Research InstituteNSUN7 epigenetic loss occurs in human primary HCC tumors in association with worse clinical outcome. (A) Percentage of NSUN7 methylation in the TCGA

Updated on: February 18,2024 19

Epigenetic mechanism associated with clinical outcome and therapeutic vulnerability in liver cancer

by Josep Carreras Leukaemia Research InstituteNSUN7 epigenetic loss occurs in human primary HCC tumors in association with worse clinical outcome. (A) Percentage of NSUN7 methylation in the TCGA

Updated on:February 18,2024 19

A chemistry pioneer works to improve a flawed test for a common cancer

by Clare Milliken,Northwestern UniversityKelleher says top-down proteomics provides a more comprehensiveunderstanding of human proteins than bottom-up proteomics, which is both imprecise a

Updated on: May 23,2024 5

A chemistry pioneer works to improve a flawed test for a common cancer

by Clare Milliken,Northwestern UniversityKelleher says top-down proteomics provides a more comprehensiveunderstanding of human proteins than bottom-up proteomics, which is both imprecise a

Updated on:May 23,2024 5

Novel pretargeted radionuclide therapy for HER2-expressing cancers shows promise

by Society of Nuclear Medicine and Molecular ImagingTransversal (A), coronal (B), sagittal (C) nanoSPECT/CT images and maximum intensity projection (D) obtained 30 h after injection of pretargeted&nbs

Updated on: March 06,2024 12

Novel pretargeted radionuclide therapy for HER2-expressing cancers shows promise

by Society of Nuclear Medicine and Molecular ImagingTransversal (A), coronal (B), sagittal (C) nanoSPECT/CT images and maximum intensity projection (D) obtained 30 h after injection of pretargeted&nbs

Updated on:March 06,2024 12

In the eye of the medulloblastoma

by CNRSThe medulloblastoma expresses genes normally active in the retina only, including NRL and CRX, which play a role in the formation of the tumor. Credit: Morgane Morabito / UMR3347 CNRS-Inst

Updated on: March 01,2024 18

In the eye of the medulloblastoma

by CNRSThe medulloblastoma expresses genes normally active in the retina only, including NRL and CRX, which play a role in the formation of the tumor. Credit: Morgane Morabito / UMR3347 CNRS-Inst

Updated on:March 01,2024 18

Study finds patient messages help predict medication adherence

by Paul Govern,Vanderbilt UniversityCredit: CC0 Public DomainAround two-thirds of patients treated for breast cancer will have had hormone-sensitive tumors and, after their initial treatment, wi

Updated on: March 06,2024 20

Study finds patient messages help predict medication adherence

by Paul Govern,Vanderbilt UniversityCredit: CC0 Public DomainAround two-thirds of patients treated for breast cancer will have had hormone-sensitive tumors and, after their initial treatment, wi

Updated on:March 06,2024 20

Invention makes biopsies less invasive and more informative

by National University of SingaporeThe new STAMP technology developed by Assistant Professor Shao Huilin (left), doctoral student Mr Noah Sundah (right) and their team from NUS Institute for Heal

Updated on: April 18,2024 20

Invention makes biopsies less invasive and more informative

by National University of SingaporeThe new STAMP technology developed by Assistant Professor Shao Huilin (left), doctoral student Mr Noah Sundah (right) and their team from NUS Institute for Heal

Updated on:April 18,2024 20

Long-term cardiomyopathy risk varies by chemo agent

(HealthDay)—Long-term cardiomyopathy risk varies by chemotherapy agent for childhood cancer survivors, with a decreased risk for daunorubicin versus doxorubicin, according to a study recently publishe

Updated on: April 18,2024 11

Long-term cardiomyopathy risk varies by chemo agent

(HealthDay)—Long-term cardiomyopathy risk varies by chemotherapy agent for childhood cancer survivors, with a decreased risk for daunorubicin versus doxorubicin, according to a study recently publishe

Updated on:April 18,2024 11

Researchers present advance in re-treatment with CAR T therapy

by Perelman School of Medicine at the University of PennsylvaniaHodgkin lymphoma, nodular lymphocyte predominant (high-power view) Credit: Gabriel Caponetti, MD./Wikipedia/CC BY-SA 3.0Researchers

Updated on: February 23,2024 13

Researchers present advance in re-treatment with CAR T therapy

by Perelman School of Medicine at the University of PennsylvaniaHodgkin lymphoma, nodular lymphocyte predominant (high-power view) Credit: Gabriel Caponetti, MD./Wikipedia/CC BY-SA 3.0Researchers

Updated on:February 23,2024 13

Researchers discover coffee drinkers could halve their risk of liver cancer

by Queen's UniversityCredit: CC0 Public DomainA research team from Queen's University has found that coffee drinkers have a lower risk of the most common type of liver cancer, hepatocellu

Updated on: June 24,2024 6

Researchers discover coffee drinkers could halve their risk of liver cancer

by Queen's UniversityCredit: CC0 Public DomainA research team from Queen's University has found that coffee drinkers have a lower risk of the most common type of liver cancer, hepatocellu

Updated on:June 24,2024 6

New molecule reduces the aggressiveness of pediatric cancer

by André Julião,FAPESPA microRNA inhibitor identified by researchers at the FAPESP-supported Human Genome and Stem Cell Research Center reduced the sizes of aggressive tumors and improved

Updated on: March 06,2024 14

New molecule reduces the aggressiveness of pediatric cancer

by André Julião,FAPESPA microRNA inhibitor identified by researchers at the FAPESP-supported Human Genome and Stem Cell Research Center reduced the sizes of aggressive tumors and improved

Updated on:March 06,2024 14