Reprogramming cancer cells into immune defenders

by Tove Smeds,Lund UniversityDolly the sheep determined Filipe Pereira’s future career. The choice was between becoming an architect or a scientist, when one of the world’s most extreme examples

Updated on: December 26,2023

Reprogramming cancer cells into immune defenders

by Tove Smeds,Lund UniversityDolly the sheep determined Filipe Pereira’s future career. The choice was between becoming an architect or a scientist, when one of the world’s most extreme examples

Updated on:December 26,2023

AI can be used to detect and grade prostate cancer

byKarolinska InstitutetMicrograph showing prostatic acinar adenocarcinoma (the most common form of prostate cancer) Credit: Wikipedia,CC BY-SA 3.0Researchers at Karolinska Institutet in Sw

Updated on: December 22,2023

AI can be used to detect and grade prostate cancer

byKarolinska InstitutetMicrograph showing prostatic acinar adenocarcinoma (the most common form of prostate cancer) Credit: Wikipedia,CC BY-SA 3.0Researchers at Karolinska Institutet in Sw

Updated on:December 22,2023

Cancer biomarker data is not diverse, with implications for immunotherapy patients from underrepresented groups

byCell PressCredit: Pixabay/CC0 Public DomainHigh tumor mutational burden—the number of mutations found inside cancer cells—may not generalize as an accurate biomarker across diverse cancer pati

Updated on: December 18,2023

Cancer biomarker data is not diverse, with implications for immunotherapy patients from underrepresented groups

byCell PressCredit: Pixabay/CC0 Public DomainHigh tumor mutational burden—the number of mutations found inside cancer cells—may not generalize as an accurate biomarker across diverse cancer pati

Updated on:December 18,2023

Refined method to peer into cancer cells' inner working unlocks the interactome

byJosep Carreras Leukaemia Research InstituteliCHi-C identifies cell types presumably implicated in disease etiology. A Enrichment of GWAS summary statistics at promoter-interacting regions (PIR

Updated on: December 26,2023

Refined method to peer into cancer cells' inner working unlocks the interactome

byJosep Carreras Leukaemia Research InstituteliCHi-C identifies cell types presumably implicated in disease etiology. A Enrichment of GWAS summary statistics at promoter-interacting regions (PIR

Updated on:December 26,2023

Scientists develop a peptide that targets lung tumors and delivers therapeutics inside cells

bySRI InternationalMonomeric and tetrameric MGS4 have similar binding, internalization and subcellular location. a, Binding and internalization of tetrameric MGS4_V1 and monomeric MGS4_V2 on liv

Updated on: December 27,2023

Scientists develop a peptide that targets lung tumors and delivers therapeutics inside cells

bySRI InternationalMonomeric and tetrameric MGS4 have similar binding, internalization and subcellular location. a, Binding and internalization of tetrameric MGS4_V1 and monomeric MGS4_V2 on liv

Updated on:December 27,2023

Scientists identify potential drug target for BRCA-mutated tumours

byInstitute of Cancer ResearchCrystal structure of EXD2 exonuclease domain in spacefill format. Credit: Image generated fromPDBA new study has uncovered a previously unknown role for the e

Updated on: December 22,2023

Scientists identify potential drug target for BRCA-mutated tumours

byInstitute of Cancer ResearchCrystal structure of EXD2 exonuclease domain in spacefill format. Credit: Image generated fromPDBA new study has uncovered a previously unknown role for the e

Updated on:December 22,2023

Drugs for treating breast cancer in women are effective and well tolerated in men

byEuropean Society for Medical OncologyThere is growing evidence that drugs approved for the treatment of breast cancer in women are also effective and well tolerated in men, according to the la

Updated on: December 18,2023

Drugs for treating breast cancer in women are effective and well tolerated in men

byEuropean Society for Medical OncologyThere is growing evidence that drugs approved for the treatment of breast cancer in women are also effective and well tolerated in men, according to the la

Updated on:December 18,2023

Precision oncology approach shows potential for high grade gliomas harboring a genetic mutation

by Nicole Fawcett,University of MichiganImmunostaining in a genetically engineered pediatric high grade glioma model harboring the H3-G34R mutation. Tumor cells are shown in green, nuclei in blu

Updated on: December 26,2023

Precision oncology approach shows potential for high grade gliomas harboring a genetic mutation

by Nicole Fawcett,University of MichiganImmunostaining in a genetically engineered pediatric high grade glioma model harboring the H3-G34R mutation. Tumor cells are shown in green, nuclei in blu

Updated on:December 26,2023

Measuring changes in brain tissue oxygenation for personalized cancer radiotherapy

bySPIEResearchers used a functional near-infrared spectroscopy (fNIRS) device attached to the patient's forehead to measure changes in hemoglobin and tissue oxygenation levels. The device wa

Updated on: December 19,2023

Measuring changes in brain tissue oxygenation for personalized cancer radiotherapy

bySPIEResearchers used a functional near-infrared spectroscopy (fNIRS) device attached to the patient's forehead to measure changes in hemoglobin and tissue oxygenation levels. The device wa

Updated on:December 19,2023

KIT Inhibitors Lead to Shift in Treatment of Systemic Mastocytosis

September 26, 2023Pankit Vachhani, MDPrithviraj Bose, MDThe hematologic neoplasm systemic mastocytosis is marked by the clonal proliferation of mast cells in the skin, bone marrow, gastrointestinal tr

Updated on: October 24,2023

KIT Inhibitors Lead to Shift in Treatment of Systemic Mastocytosis

September 26, 2023Pankit Vachhani, MDPrithviraj Bose, MDThe hematologic neoplasm systemic mastocytosis is marked by the clonal proliferation of mast cells in the skin, bone marrow, gastrointestinal tr

Updated on:October 24,2023

'Ray of hope': New advances in fighting a range of cancers

Credit: Pixabay/CC0 Public DomainNew advances in the fight against a range of cancers have been revealed at the annual meeting of the American Society of Clinical Oncology (ASCO), which wraps up in Ch

Updated on: January 10,2024

'Ray of hope': New advances in fighting a range of cancers

Credit: Pixabay/CC0 Public DomainNew advances in the fight against a range of cancers have been revealed at the annual meeting of the American Society of Clinical Oncology (ASCO), which wraps up in Ch

Updated on:January 10,2024

Entrectinib effective, well-tolerated against ROS1 and NTRK lung cancers, especially with brain metastases

by Garth Sundem,CU Anschutz Medical CampusRobert C. Doebele, MD, PhD. Credit: CU Anschutz Medical CampusPooled analysis of three phase 1 and 2 clinical trials published online ahead of print in

Updated on: December 22,2023

Entrectinib effective, well-tolerated against ROS1 and NTRK lung cancers, especially with brain metastases

by Garth Sundem,CU Anschutz Medical CampusRobert C. Doebele, MD, PhD. Credit: CU Anschutz Medical CampusPooled analysis of three phase 1 and 2 clinical trials published online ahead of print in

Updated on:December 22,2023