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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Study hints at why an aggressive form of brain cancer is hard to treat

Study hints at why an aggressive form of brain cancer is hard to treat

by Abbey Bigler,Broad Institute of MIT and HarvardAn illustration representing the cellular states of glioblastoma. Credit: Sébastien PerroudGlioblastoma is an incurable brain cancer that kills

Study hints at why an aggressive form of brain cancer is hard to treat

by Abbey Bigler,Broad Institute of MIT and HarvardAn illustration representing the cellular states of glioblastoma. Credit: Sébastien PerroudGlioblastoma is an incurable brain cancer that kills
Five key medical advances related to bone marrow transplantation

Five key medical advances related to bone marrow transplantation

by Heather Carlson Kehren,Mayo ClinicCredit: Mayo ClinicIn the six decades since blood and marrow transplantation was used to treat patients with blood cancers, this once experimental treatment

Five key medical advances related to bone marrow transplantation

by Heather Carlson Kehren,Mayo ClinicCredit: Mayo ClinicIn the six decades since blood and marrow transplantation was used to treat patients with blood cancers, this once experimental treatment
Scientists discover a new way to prevent secondary breast cancer

Scientists discover a new way to prevent secondary breast cancer

byInstitute of Cancer ResearchCredit: Pixabay/CC0 Public DomainScientists have discovered why breast cancer cells that have spread to the lungs may "wake up" following years of sleep,

Scientists discover a new way to prevent secondary breast cancer

byInstitute of Cancer ResearchCredit: Pixabay/CC0 Public DomainScientists have discovered why breast cancer cells that have spread to the lungs may "wake up" following years of sleep,
Study finds calcium, vitamin D supplements may reduce cancer mortality in long term

Study finds calcium, vitamin D supplements may reduce cancer mortality in long term

by Elana GotkineFor postmenopausal women, calcium and vitamin D (CaD) supplements may reduce cancer mortality and increase cardiovascular disease (CVD) mortality after more than 20 years of follow-up,

Study finds calcium, vitamin D supplements may reduce cancer mortality in long term

by Elana GotkineFor postmenopausal women, calcium and vitamin D (CaD) supplements may reduce cancer mortality and increase cardiovascular disease (CVD) mortality after more than 20 years of follow-up,
Researchers map the effects of all potential changes in key cancer gene

Researchers map the effects of all potential changes in key cancer gene

byThe Francis Crick InstituteFunction scores capture fitness effects mediated at both the transcript and protein 457 level. Credit: Megan Buckley et alResearchers at the Francis Crick Institute

Researchers map the effects of all potential changes in key cancer gene

byThe Francis Crick InstituteFunction scores capture fitness effects mediated at both the transcript and protein 457 level. Credit: Megan Buckley et alResearchers at the Francis Crick Institute
Major pathologic response to neoadjuvant pembrolizumab in advanced melanoma trial exceeds 50%

Major pathologic response to neoadjuvant pembrolizumab in advanced melanoma trial exceeds 50%

by SWOG Cancer Research NetworkCredit: CC0 Public DomainIn exploratory analyses of results from the SWOG S1801 trial in patients with stage III-IV resectable melanoma, researchers saw a major patholog

Major pathologic response to neoadjuvant pembrolizumab in advanced melanoma trial exceeds 50%

by SWOG Cancer Research NetworkCredit: CC0 Public DomainIn exploratory analyses of results from the SWOG S1801 trial in patients with stage III-IV resectable melanoma, researchers saw a major patholog
Adjuvant nivolumab + ipilimumab lacks efficacy for localized renal cell carcinoma

Adjuvant nivolumab + ipilimumab lacks efficacy for localized renal cell carcinoma

Disease-free survival (DFS) does not differ with adjuvant nivolumab plus ipilimumab (NIVO+IPI) compared with placebo in patients with localized renal cell carcinoma (RCC) at high risk for postnephrect

Adjuvant nivolumab + ipilimumab lacks efficacy for localized renal cell carcinoma

Disease-free survival (DFS) does not differ with adjuvant nivolumab plus ipilimumab (NIVO+IPI) compared with placebo in patients with localized renal cell carcinoma (RCC) at high risk for postnephrect
Inhibition of prmt5 by repurposing market drugs: A fresh therapeutic pathway for cancer treatment

Inhibition of prmt5 by repurposing market drugs: A fresh therapeutic pathway for cancer treatment

by TranSpreadDevelopment of AlphaLISA HTS screen to identify specific PRMT5 inhibitors. (A) Principle of AlphaLISA technique adapted to HTS. Biotinylated histone H4 (a well-known PRMT5 substrate) was

Inhibition of prmt5 by repurposing market drugs: A fresh therapeutic pathway for cancer treatment

by TranSpreadDevelopment of AlphaLISA HTS screen to identify specific PRMT5 inhibitors. (A) Principle of AlphaLISA technique adapted to HTS. Biotinylated histone H4 (a well-known PRMT5 substrate) was
Could artificial sweeteners alter your microbiome?

Could artificial sweeteners alter your microbiome?

by Dennis ThompsonYou may think that artificial sweeteners can help you lose some weight, but a new study finds they are no good for your gut's microbiome.People who useaspartame(Equal

Could artificial sweeteners alter your microbiome?

by Dennis ThompsonYou may think that artificial sweeteners can help you lose some weight, but a new study finds they are no good for your gut's microbiome.People who useaspartame(Equal
Research details adaptation tactics of pancreatic cancer

Research details adaptation tactics of pancreatic cancer

byUniversity of OklahomaPSCs support cancer cell growth by the secretion of acetate under acidosis. Credit:Nature Cell Biology(2024). DOI: 10.1038/s41556-024-01372-4Like alien invade

Research details adaptation tactics of pancreatic cancer

byUniversity of OklahomaPSCs support cancer cell growth by the secretion of acetate under acidosis. Credit:Nature Cell Biology(2024). DOI: 10.1038/s41556-024-01372-4Like alien invade
New method for early detection of multi-cancers based on human metabolism

New method for early detection of multi-cancers based on human metabolism

bySwedish Research CouncilValidation of the pruned combined free GAGome MCED score. (A) Validation study subject flow (see also SI Appendix, Fig. S17). (B) Pruned combined free GAGome MCED score

New method for early detection of multi-cancers based on human metabolism

bySwedish Research CouncilValidation of the pruned combined free GAGome MCED score. (A) Validation study subject flow (see also SI Appendix, Fig. S17). (B) Pruned combined free GAGome MCED score
Patient step counts predict lung cancer treatment outcomes, study finds

Patient step counts predict lung cancer treatment outcomes, study finds

byAmerican Society for Radiation OncologyCredit: CC0 Public DomainNumerous studies have shown that monitoring physical activity promotes better health—from reducing body mass index to watching f

Patient step counts predict lung cancer treatment outcomes, study finds

byAmerican Society for Radiation OncologyCredit: CC0 Public DomainNumerous studies have shown that monitoring physical activity promotes better health—from reducing body mass index to watching f