How genetic therapies transformed the lives of sickle cell patients

Credit: CC0 Public DomainTheir stories are divided into before and after. First, those long years of pain which flooded every moment—school, relationships, work.And then—after agonizing treatments—wha

Updated on: March 27,2024 0

How genetic therapies transformed the lives of sickle cell patients

Credit: CC0 Public DomainTheir stories are divided into before and after. First, those long years of pain which flooded every moment—school, relationships, work.And then—after agonizing treatments—wha

Updated on:March 27,2024 0

Significant proportion of cancer drugs lack proof of added benefit, finds study

by British Medical JournalCredit: CC0 Public DomainMany cancer drugs approved by the European Medicines Agency (EMA) between 1995 and 2020 lack proof of added benefit, particularly those approved

Updated on: May 26,2024 3

Significant proportion of cancer drugs lack proof of added benefit, finds study

by British Medical JournalCredit: CC0 Public DomainMany cancer drugs approved by the European Medicines Agency (EMA) between 1995 and 2020 lack proof of added benefit, particularly those approved

Updated on:May 26,2024 3

Here's why some high-risk patients aren't getting drugs to combat COVID

by Emily Alpert Reyes, Los Angeles TimesCredit: Unsplash/CC0 Public DomainAs the toll from the COVID-19 pandemic continued to mount, antiviral medications such as Paxlovid were hailed by health offici

Updated on: May 26,2024 3

Here's why some high-risk patients aren't getting drugs to combat COVID

by Emily Alpert Reyes, Los Angeles TimesCredit: Unsplash/CC0 Public DomainAs the toll from the COVID-19 pandemic continued to mount, antiviral medications such as Paxlovid were hailed by health offici

Updated on:May 26,2024 3

Addition of durvalumab, bevacizumab to TACE beneficial in liver cancer

by Elana GotkineFor patients with embolization-eligible unresectable hepatocellular carcinoma (uHCC), the addition of durvalumab (D) and bevacizumab (B) to transarterial chemoembolization (TACE) impro

Updated on: March 22,2024 12

Addition of durvalumab, bevacizumab to TACE beneficial in liver cancer

by Elana GotkineFor patients with embolization-eligible unresectable hepatocellular carcinoma (uHCC), the addition of durvalumab (D) and bevacizumab (B) to transarterial chemoembolization (TACE) impro

Updated on:March 22,2024 12

Exploring the biology of 'double positive' T cells

byLudwig Cancer ResearchCredit: CC0 Public DomainThe molecular markers CD4 and CD8—defining helper T cells and killer T cells, respectively—were once considered mutually exclusive. But "dou

Updated on: January 07,2024 25

Exploring the biology of 'double positive' T cells

byLudwig Cancer ResearchCredit: CC0 Public DomainThe molecular markers CD4 and CD8—defining helper T cells and killer T cells, respectively—were once considered mutually exclusive. But "dou

Updated on:January 07,2024 25

Understanding breast cancer recurrence, metastatic spread

byUniversity of CincinnatiCredit: Unsplash/CC0 Public DomainDespite advancements in cancer detection and treatment, breast cancer that comes back or spreads still presents a challenge to researc

Updated on: December 28,2023 13

Understanding breast cancer recurrence, metastatic spread

byUniversity of CincinnatiCredit: Unsplash/CC0 Public DomainDespite advancements in cancer detection and treatment, breast cancer that comes back or spreads still presents a challenge to researc

Updated on:December 28,2023 13

Existing cancer drug ponatinib could be repurposed to fight certain aggressive cancers

byNanyang Technological UniversitySchematic summary of mechanisms of action of ponatinib in ALT cells. Ponatinib disrupts alternative lengthening of telomeres mechanisms by inducing telomeric C-

Updated on: January 10,2024 9

Existing cancer drug ponatinib could be repurposed to fight certain aggressive cancers

byNanyang Technological UniversitySchematic summary of mechanisms of action of ponatinib in ALT cells. Ponatinib disrupts alternative lengthening of telomeres mechanisms by inducing telomeric C-

Updated on:January 10,2024 9

Five key medical advances related to bone marrow transplantation

by Heather Carlson Kehren,Mayo ClinicCredit: Mayo ClinicIn the six decades since blood and marrow transplantation was used to treat patients with blood cancers, this once experimental treatment

Updated on: January 30,2024 16

Five key medical advances related to bone marrow transplantation

by Heather Carlson Kehren,Mayo ClinicCredit: Mayo ClinicIn the six decades since blood and marrow transplantation was used to treat patients with blood cancers, this once experimental treatment

Updated on:January 30,2024 16

Risk model identifies metastatic cancer patients who may benefit from immune checkpoint inhibitors

byUniversity of Eastern FinlandSurvival of the patients according to the risk scores. Kaplan-Meier curves illustrating overall survival (OS) (a) and progression-free survival (PFS) (b) according

Updated on: January 25,2024 24

Risk model identifies metastatic cancer patients who may benefit from immune checkpoint inhibitors

byUniversity of Eastern FinlandSurvival of the patients according to the risk scores. Kaplan-Meier curves illustrating overall survival (OS) (a) and progression-free survival (PFS) (b) according

Updated on:January 25,2024 24

Two-pronged immunotherapy eliminates metastatic breast cancer in mice

by Julia Evangelou Strait,Washington University School of MedicineResearchers at Washington University School of Medicine in St. Louis have identified a way to sensitize metastatic breast cancer

Updated on: January 04,2024 6

Two-pronged immunotherapy eliminates metastatic breast cancer in mice

by Julia Evangelou Strait,Washington University School of MedicineResearchers at Washington University School of Medicine in St. Louis have identified a way to sensitize metastatic breast cancer

Updated on:January 04,2024 6

AI is capable of detecting incidental lung cancer in written medical reports

by D'Or Institute for Research and EducationAn example of our information extraction algorithm. (A) Initial dependency tree. (B) Final information chunks. Credit:JCO Global Oncology(20

Updated on: January 06,2024 11

AI is capable of detecting incidental lung cancer in written medical reports

by D'Or Institute for Research and EducationAn example of our information extraction algorithm. (A) Initial dependency tree. (B) Final information chunks. Credit:JCO Global Oncology(20

Updated on:January 06,2024 11

Less than half of pregnant women get the flu shot: New data from UPMC Children's might change that

by Abby Mackey, Pittsburgh Post-GazetteCredit: Unsplash/CC0 Public DomainJohn Williams knows the risks associated with riding motorcycles, but they don't deter him. Neither do warnings from physic

Updated on: March 25,2024 10

Less than half of pregnant women get the flu shot: New data from UPMC Children's might change that

by Abby Mackey, Pittsburgh Post-GazetteCredit: Unsplash/CC0 Public DomainJohn Williams knows the risks associated with riding motorcycles, but they don't deter him. Neither do warnings from physic

Updated on:March 25,2024 10