Tiny, implantable therapeutic sponge device helps kill cancer in mice

by Wayne Lewis,University of California, Los AngelesThe SymphNode device (left), contains nanoparticles (red dots) that release a drug that blocks the activity of regulatory T cells (green), whi

Updated on: January 08,2024 10

Tiny, implantable therapeutic sponge device helps kill cancer in mice

by Wayne Lewis,University of California, Los AngelesThe SymphNode device (left), contains nanoparticles (red dots) that release a drug that blocks the activity of regulatory T cells (green), whi

Updated on:January 08,2024 10

Supercharging CAR-T cells for cancer treatment

byEcole Polytechnique Federale de LausanneIL-10-expressing CAR T cells counter dysfunction in tumors.a, Schematic depicting the HER2 CAR and IL-10 HER2 CAR constructs; scFv, single-chain v

Updated on: January 26,2024 16

Supercharging CAR-T cells for cancer treatment

byEcole Polytechnique Federale de LausanneIL-10-expressing CAR T cells counter dysfunction in tumors.a, Schematic depicting the HER2 CAR and IL-10 HER2 CAR constructs; scFv, single-chain v

Updated on:January 26,2024 16

Study suggests the possibility of combination therapy of SORA and FGF21 in hepatocellular carcinoma

by Higher Education PressFGF21 combined with SORA promotes apoptosis and inhibits proliferation of 7721‐Smad3 cells under anaerobic conditions. Credit: Ting Zhang, Huiling Shi, Shihui Zhang, Qin Zhu,

Updated on: May 16,2024 7

Study suggests the possibility of combination therapy of SORA and FGF21 in hepatocellular carcinoma

by Higher Education PressFGF21 combined with SORA promotes apoptosis and inhibits proliferation of 7721‐Smad3 cells under anaerobic conditions. Credit: Ting Zhang, Huiling Shi, Shihui Zhang, Qin Zhu,

Updated on:May 16,2024 7

Molecular jackhammers drill pathway to killing cancer cells  

JANUARY 19, 2024by Michelle Revels,Texas A&M University College of EngineeringResearchers have developed a technique that employs nanoscopic molecular jackhammers capable of cracking a cell&

Updated on: March 15,2024 7

Molecular jackhammers drill pathway to killing cancer cells  

JANUARY 19, 2024by Michelle Revels,Texas A&M University College of EngineeringResearchers have developed a technique that employs nanoscopic molecular jackhammers capable of cracking a cell&

Updated on:March 15,2024 7

Study: Key mechanisms of action differences in immune checkpoint inhibitor combination therapies for advanced melanoma

byH. Lee Moffitt Cancer Center & Research InstituteProposed mechanism of the two ICI combinations. Graphic created with Biorender (biorender.com). ICI, immune checkpoint inhibitor. Credit:&n

Updated on: January 25,2024 20

Study: Key mechanisms of action differences in immune checkpoint inhibitor combination therapies for advanced melanoma

byH. Lee Moffitt Cancer Center & Research InstituteProposed mechanism of the two ICI combinations. Graphic created with Biorender (biorender.com). ICI, immune checkpoint inhibitor. Credit:&n

Updated on:January 25,2024 20

Can what works to treat cancer work for diabetes?

by Jess Berthold,University of California, San FranciscoCredit: CC0 Public DomainTo live with type 1 diabetes is to be ruled by relentless routine. Food must be carefully monitored, and the only

Updated on: January 30,2024 15

Can what works to treat cancer work for diabetes?

by Jess Berthold,University of California, San FranciscoCredit: CC0 Public DomainTo live with type 1 diabetes is to be ruled by relentless routine. Food must be carefully monitored, and the only

Updated on:January 30,2024 15

Lymphoma mutation yields super-competitive immune cells

by Heather Lindsey,Cornell UniversitySupercompetition in germinal centers leads to aggressive B cell lymphomas. GC B cells vigorously compete against each other to receive limiting T cell help,

Updated on: December 28,2023 10

Lymphoma mutation yields super-competitive immune cells

by Heather Lindsey,Cornell UniversitySupercompetition in germinal centers leads to aggressive B cell lymphomas. GC B cells vigorously compete against each other to receive limiting T cell help,

Updated on:December 28,2023 10

Taking a closer look at eye cancer: Research offers new insight into high rate of metastasis

byEdith Cowan UniversityCredit: Marc Schulte from PexelsNew research from Edith Cowan University (ECU) is one step closer to understanding why uveal melanoma, the deadliest form of eye cancer, h

Updated on: August 01,2024 0

Taking a closer look at eye cancer: Research offers new insight into high rate of metastasis

byEdith Cowan UniversityCredit: Marc Schulte from PexelsNew research from Edith Cowan University (ECU) is one step closer to understanding why uveal melanoma, the deadliest form of eye cancer, h

Updated on:August 01,2024 0

12.8 percent of unique prescribers prescribed topical antifungals in 2021

by Elana GotkineIn 2021, 12.8 percent of unique prescribers in Medicare Part D prescribed topical antifungals, with about 6.5 million topical antifungal prescriptions filled, at a total cost of $231 m

Updated on: March 22,2024 17

12.8 percent of unique prescribers prescribed topical antifungals in 2021

by Elana GotkineIn 2021, 12.8 percent of unique prescribers in Medicare Part D prescribed topical antifungals, with about 6.5 million topical antifungal prescriptions filled, at a total cost of $231 m

Updated on:March 22,2024 17

Vitamin C may hold the key to improve efficacy of dendritic cell-derived anticancer cell therapies

byJosep Carreras Leukaemia Research InstituteVitamin C-mediated dendritic cell DNA methylome remodeling. (A) Scheme depicting the experimental setup. Monocytes (MO) were differentiated to dendri

Updated on: January 08,2024 9

Vitamin C may hold the key to improve efficacy of dendritic cell-derived anticancer cell therapies

byJosep Carreras Leukaemia Research InstituteVitamin C-mediated dendritic cell DNA methylome remodeling. (A) Scheme depicting the experimental setup. Monocytes (MO) were differentiated to dendri

Updated on:January 08,2024 9

Boosting the cancer-destroying ability of killer T-cells

by Julia Short,Cardiff UniversityCredit: CC0 Public DomainMore types of cancer could potentially be destroyed by patients' own immune cells, thanks to new research by Cardiff University.The

Updated on: April 18,2024 13

Boosting the cancer-destroying ability of killer T-cells

by Julia Short,Cardiff UniversityCredit: CC0 Public DomainMore types of cancer could potentially be destroyed by patients' own immune cells, thanks to new research by Cardiff University.The

Updated on:April 18,2024 13

How do we overcome treatment resistance in a sarcoma cancer with already limited treatment options?

by Elena Daviter-Nowell,Institute of Cancer ResearchHistopathology image of leiomyosarcoma. Credit:Wikimedia Commons, CC-BY-SA 4.0Leiomyosarcoma is a type of soft tissue sarcoma that is ha

Updated on: January 10,2024 8

How do we overcome treatment resistance in a sarcoma cancer with already limited treatment options?

by Elena Daviter-Nowell,Institute of Cancer ResearchHistopathology image of leiomyosarcoma. Credit:Wikimedia Commons, CC-BY-SA 4.0Leiomyosarcoma is a type of soft tissue sarcoma that is ha

Updated on:January 10,2024 8