Experts reach consensus on gene therapy carcinogenicity risks

byMary Ann Liebert, IncCredit: CC0 Public DomainAnarticlein the journalHuman Gene Therapydescribes the consensus reached by invited experts who participated in a meeting

Updated on: September 03,2024

Experts reach consensus on gene therapy carcinogenicity risks

byMary Ann Liebert, IncCredit: CC0 Public DomainAnarticlein the journalHuman Gene Therapydescribes the consensus reached by invited experts who participated in a meeting

Updated on:September 03,2024

Clinical trial shows durvalumab plus ceralasertib boosted immune response in lung cancer patients

by University of Texas M. D. Anderson Cancer CenterCredit: Unsplash/CC0 Public DomainA specific combination of targeted therapy and immunotherapy may better help patients with non-small cell lung

Updated on: May 09,2024

Clinical trial shows durvalumab plus ceralasertib boosted immune response in lung cancer patients

by University of Texas M. D. Anderson Cancer CenterCredit: Unsplash/CC0 Public DomainA specific combination of targeted therapy and immunotherapy may better help patients with non-small cell lung

Updated on:May 09,2024

Study reveals gene 'switched off' in early stages of pancreatic cancer allows rapid tumor growth and spread

byNottingham Trent UniversityHNF4A is methylated and suppressed in pancreatic cancer. Credit:Gastro Hep Advances(2024). DOI: 10.1016/j.gastha.2024.04.005Scientists at Nottingham Tren

Updated on: July 17,2024

Study reveals gene 'switched off' in early stages of pancreatic cancer allows rapid tumor growth and spread

byNottingham Trent UniversityHNF4A is methylated and suppressed in pancreatic cancer. Credit:Gastro Hep Advances(2024). DOI: 10.1016/j.gastha.2024.04.005Scientists at Nottingham Tren

Updated on:July 17,2024

Study examines treatment options for women with recurrent ovarian cancer

by WileyIntermediate magnification micrograph of a low malignant potential (LMP) mucinous ovarian tumour. H&E stain. The micrograph shows: Simple mucinous epithelium (right) and mucinous epit

Updated on: June 01,2024

Study examines treatment options for women with recurrent ovarian cancer

by WileyIntermediate magnification micrograph of a low malignant potential (LMP) mucinous ovarian tumour. H&E stain. The micrograph shows: Simple mucinous epithelium (right) and mucinous epit

Updated on:June 01,2024

Discovery could lead to better treatment for leukemia

by University of Illinois at ChicagoBone marrow aspirate showing acute myeloid leukemia. Several blasts have Auer rods. Credit: WikipediaPrevious research has revealed that patients with acute my

Updated on: April 14,2024

Discovery could lead to better treatment for leukemia

by University of Illinois at ChicagoBone marrow aspirate showing acute myeloid leukemia. Several blasts have Auer rods. Credit: WikipediaPrevious research has revealed that patients with acute my

Updated on:April 14,2024

The paradoxical role of white blood cells in the spread of breast cancer

byKarolinska InstitutetCredit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.113507A new study from Karolinska Institutet,publishedinCell Reports, shows that tumor-

Updated on: January 26,2024

The paradoxical role of white blood cells in the spread of breast cancer

byKarolinska InstitutetCredit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.113507A new study from Karolinska Institutet,publishedinCell Reports, shows that tumor-

Updated on:January 26,2024

Denmark can save lives and costs by reducing nitrate in drinking water, researchers say

by University of CopenhagenThe annual net gain from a lower nitrate water standard based on whether the current nitrate concentrations are above or below 3.87 mg/L. Credit:Science of The To

Updated on: June 06,2024

Denmark can save lives and costs by reducing nitrate in drinking water, researchers say

by University of CopenhagenThe annual net gain from a lower nitrate water standard based on whether the current nitrate concentrations are above or below 3.87 mg/L. Credit:Science of The To

Updated on:June 06,2024

Cellular 'fingerprint' may offer early warning of cancer risk

by Isabella Backman,Yale UniversityCellDRIFT is turned back upon reprogramming in human fibroblasts, but is not stabilized with additional passages. (A) Scatterplot showing reprogramming traject

Updated on: January 10,2024

Cellular 'fingerprint' may offer early warning of cancer risk

by Isabella Backman,Yale UniversityCellDRIFT is turned back upon reprogramming in human fibroblasts, but is not stabilized with additional passages. (A) Scatterplot showing reprogramming traject

Updated on:January 10,2024

Discovery could lead to 'kinder' treatment for childhood neuroblastoma

by University of CambridgeA ball of neuroblastoma cells forming mature nerves after drug treatment. Credit: Kirsty Ferguson/Developmental CellChildren with neuroblastoma—responsible for 15% of ca

Updated on: March 23,2024

Discovery could lead to 'kinder' treatment for childhood neuroblastoma

by University of CambridgeA ball of neuroblastoma cells forming mature nerves after drug treatment. Credit: Kirsty Ferguson/Developmental CellChildren with neuroblastoma—responsible for 15% of ca

Updated on:March 23,2024

A predictive biomarker of response to therapy in patients with microsatellite stable metastatic colorectal cancer

by Vall d'Hebron Institute of OncologyA total of 166 patients with mCRCBRAF-V600Ewere included in the study from discovery (n = 46), validation (n = 52) and control (n = 68) cohorts. WES of

Updated on: January 08,2024

A predictive biomarker of response to therapy in patients with microsatellite stable metastatic colorectal cancer

by Vall d'Hebron Institute of OncologyA total of 166 patients with mCRCBRAF-V600Ewere included in the study from discovery (n = 46), validation (n = 52) and control (n = 68) cohorts. WES of

Updated on:January 08,2024

Billions spent on cancer research but only small percentage goes to treatment, study shows

by University of SouthamptonFunding per year by type of science (A) and proportion of funding per year by type of science (B). Credit:The Lancet Oncology(2023). DOI: 10.1016/S1470-204

Updated on: January 30,2024

Billions spent on cancer research but only small percentage goes to treatment, study shows

by University of SouthamptonFunding per year by type of science (A) and proportion of funding per year by type of science (B). Credit:The Lancet Oncology(2023). DOI: 10.1016/S1470-204

Updated on:January 30,2024

How genome doubling helps cancer develop

byEcole Polytechnique Federale de LausanneChromosomes in cells with whole genome doubling. Credit: Elisa Oricchio/Giovanni Ciriello (EPFL/UNIL)A single cell contains 2-3 meters of DNA, meaning t

Updated on: December 25,2023

How genome doubling helps cancer develop

byEcole Polytechnique Federale de LausanneChromosomes in cells with whole genome doubling. Credit: Elisa Oricchio/Giovanni Ciriello (EPFL/UNIL)A single cell contains 2-3 meters of DNA, meaning t

Updated on:December 25,2023