Computational method used to directly measure tumors shows hypertranscription is ubiquitous across cancers

by Bob Yirka , Medical XpressOverview of RNA output analysis with RNAmp. (A) Hypertranscription occurs when cancer cells elevate their RNA output above normal cell levels (left). Upon RNA extraction f

Updated on: February 20,2024

Computational method used to directly measure tumors shows hypertranscription is ubiquitous across cancers

by Bob Yirka , Medical XpressOverview of RNA output analysis with RNAmp. (A) Hypertranscription occurs when cancer cells elevate their RNA output above normal cell levels (left). Upon RNA extraction f

Updated on:February 20,2024

How conquering a rare leukemia in children revolutionized cancer care for millions

by Marie McculloughFifty years ago, children with an aggressive form of leukemia went from diagnosis to death in a few months, as the disease rampaged through their lymph nodes, spleens, livers, and n

Updated on: March 01,2024

How conquering a rare leukemia in children revolutionized cancer care for millions

by Marie McculloughFifty years ago, children with an aggressive form of leukemia went from diagnosis to death in a few months, as the disease rampaged through their lymph nodes, spleens, livers, and n

Updated on:March 01,2024

Creating a 'parts list' for cancer's spread, with help from a worm

by Duke UniversityA tiny worm cell breaking through the wall that normally holds cells in place. Credit:Development(2023). DOI: 10.1242/dev.201570What makes some cancer cells stay put

Updated on: January 30,2024

Creating a 'parts list' for cancer's spread, with help from a worm

by Duke UniversityA tiny worm cell breaking through the wall that normally holds cells in place. Credit:Development(2023). DOI: 10.1242/dev.201570What makes some cancer cells stay put

Updated on:January 30,2024

Researchers unlock mysteries of complex microRNA oncogenes

by McGill UniversityMicroRNA and mRNA visualization in differentiating C1C12 cells. Credit: Ryan Jeffs/WikipediaMicroRNAs are tiny molecules of nucleic acid that control gene expression, acting l

Updated on: June 11,2024

Researchers unlock mysteries of complex microRNA oncogenes

by McGill UniversityMicroRNA and mRNA visualization in differentiating C1C12 cells. Credit: Ryan Jeffs/WikipediaMicroRNAs are tiny molecules of nucleic acid that control gene expression, acting l

Updated on:June 11,2024

Moderate exercise helps colorectal cancer patients live longer by reducing inflammation and improving gut bacteria

by Heather Simonsen,University of UtahCredit: Pixabay/CC0 Public DomainRegular physical activity can extend colorectal cancer patients' lives. In a first-ever study, scientists looked at the

Updated on: January 04,2024

Moderate exercise helps colorectal cancer patients live longer by reducing inflammation and improving gut bacteria

by Heather Simonsen,University of UtahCredit: Pixabay/CC0 Public DomainRegular physical activity can extend colorectal cancer patients' lives. In a first-ever study, scientists looked at the

Updated on:January 04,2024

Secret vulnerabilities of cancer's 'Death Star' protein revealed

byCenter for Genomic RegulationA three-dimensional image showing the human protein KRAS (blue) interacting with RAF1 (yellow), one of its main partners. The blue-to-red colour gradient indicates

Updated on: December 30,2023

Secret vulnerabilities of cancer's 'Death Star' protein revealed

byCenter for Genomic RegulationA three-dimensional image showing the human protein KRAS (blue) interacting with RAF1 (yellow), one of its main partners. The blue-to-red colour gradient indicates

Updated on:December 30,2023

New cancer therapy takes personalized medicine to a new level

by Karen WeintraubCredit: Unsplash/CC0 Public DomainPersonalized care has been a buzzword in medicine for years, but new research on cancer treatment is taking it to a new level.Detailed in a study pu

Updated on: January 11,2024

New cancer therapy takes personalized medicine to a new level

by Karen WeintraubCredit: Unsplash/CC0 Public DomainPersonalized care has been a buzzword in medicine for years, but new research on cancer treatment is taking it to a new level.Detailed in a study pu

Updated on:January 11,2024

Overcoming the limits of immunotherapies

byUniversity of WürzburgKarl Petri (left) is setting up an Emmy Noether research group at the University Hospital of Würzburg with the support of the German Research Foundation. Alexandre Truber

Updated on: August 27,2024

Overcoming the limits of immunotherapies

byUniversity of WürzburgKarl Petri (left) is setting up an Emmy Noether research group at the University Hospital of Würzburg with the support of the German Research Foundation. Alexandre Truber

Updated on:August 27,2024

Single-cell analysis reveals how melanoma cells resist immunotherapy

by Karen Zusi,Broad Institute of MIT and HarvardCredit: Broad Institute of MIT and HarvardUnleashing the immune system to fight tumors—an approach enabled by immunotherapy—has led to remarkable

Updated on: March 12,2024

Single-cell analysis reveals how melanoma cells resist immunotherapy

by Karen Zusi,Broad Institute of MIT and HarvardCredit: Broad Institute of MIT and HarvardUnleashing the immune system to fight tumors—an approach enabled by immunotherapy—has led to remarkable

Updated on:March 12,2024

Inhibiting the biological crosstalk of autophagy and mitochondrial function underlying pancreatic ductal adenocarcinoma

by Thamarasee Jeewandara , Medical XpressAutophagy inhibition leads to a drop in the LIP in PDAC. (A) Autophagy was inhibited genetically or pharmacologically in PDAC cells, and the relative LIP was d

Updated on: February 24,2024

Inhibiting the biological crosstalk of autophagy and mitochondrial function underlying pancreatic ductal adenocarcinoma

by Thamarasee Jeewandara , Medical XpressAutophagy inhibition leads to a drop in the LIP in PDAC. (A) Autophagy was inhibited genetically or pharmacologically in PDAC cells, and the relative LIP was d

Updated on:February 24,2024

Immune system plays vital role in longer multiple myeloma remission, new study shows

byUniversity of Miami Leonard M. Miller School of MedicineStudy design and treatment outcomes. a Immune profiling was performed on blood and bone marrow collected from 23 patients with multiple

Updated on: January 12,2024

Immune system plays vital role in longer multiple myeloma remission, new study shows

byUniversity of Miami Leonard M. Miller School of MedicineStudy design and treatment outcomes. a Immune profiling was performed on blood and bone marrow collected from 23 patients with multiple

Updated on:January 12,2024

Researcher pioneers method of detecting early-stage cancer: Cheaper, faster, less invasive and accurate

by Dave Raney,University of CincinnatiJiajie Diao and his collaboratorare working with UC’s Technology Transfer team to commercialize their new method for early cancer diagnosis. Credit: C

Updated on: January 30,2024

Researcher pioneers method of detecting early-stage cancer: Cheaper, faster, less invasive and accurate

by Dave Raney,University of CincinnatiJiajie Diao and his collaboratorare working with UC’s Technology Transfer team to commercialize their new method for early cancer diagnosis. Credit: C

Updated on:January 30,2024