Drug combination shows potential in aggressive leukemia

by Blake Belden,Virginia Commonwealth UniversityAcute myelocytic leukemia (AML). Credit: Unsplash/CC0 Public DomainAcute myeloid leukemia (AML) is an aggressive form of cancer that originates in

Updated on: December 28,2023

Drug combination shows potential in aggressive leukemia

by Blake Belden,Virginia Commonwealth UniversityAcute myelocytic leukemia (AML). Credit: Unsplash/CC0 Public DomainAcute myeloid leukemia (AML) is an aggressive form of cancer that originates in

Updated on:December 28,2023

Role of cancer protein ARID1A at intersection of genome stability and tumor suppression

by The Wistar InstituteRugang Zhang, Ph.D., The Wistar Institute. Credit: The Wistar InstituteThe ARID1A tumor suppressor protein is required to maintain telomere cohesion and correct chromosome

Updated on: April 09,2024

Role of cancer protein ARID1A at intersection of genome stability and tumor suppression

by The Wistar InstituteRugang Zhang, Ph.D., The Wistar Institute. Credit: The Wistar InstituteThe ARID1A tumor suppressor protein is required to maintain telomere cohesion and correct chromosome

Updated on:April 09,2024

Researchers publish the first comprehensive, 3D analysis of the complete rhabdomyosarcoma genome

by Nationwide Children's HospitalGraphical abstract. Credit:NAR Cancer(2023). DOI: 10.1093/narcan/zcad028In a paper published inNAR Cancer, researchers from the Center for C

Updated on: January 30,2024

Researchers publish the first comprehensive, 3D analysis of the complete rhabdomyosarcoma genome

by Nationwide Children's HospitalGraphical abstract. Credit:NAR Cancer(2023). DOI: 10.1093/narcan/zcad028In a paper published inNAR Cancer, researchers from the Center for C

Updated on:January 30,2024

Rogue immune cells linked to leukemia found to be a key driver of autoimmune diseases

by Garvan Institute of Medical ResearchA killer T cell (centre) hunting a target cell. Credit: NIH Image GalleryGene variants associated with leukemia can produce "rogue" immune cells t

Updated on: February 20,2024

Rogue immune cells linked to leukemia found to be a key driver of autoimmune diseases

by Garvan Institute of Medical ResearchA killer T cell (centre) hunting a target cell. Credit: NIH Image GalleryGene variants associated with leukemia can produce "rogue" immune cells t

Updated on:February 20,2024

How do metastatic tumor cells grow in lymph nodes?

by Institute for Basic Science(Left) Schematic diagram for the mechanism of tumor lymph node metastasis.(Right) (A) Stepwise growing metastatic melanoma in tumor-draining lymph node and (B) fatty

Updated on: April 01,2024

How do metastatic tumor cells grow in lymph nodes?

by Institute for Basic Science(Left) Schematic diagram for the mechanism of tumor lymph node metastasis.(Right) (A) Stepwise growing metastatic melanoma in tumor-draining lymph node and (B) fatty

Updated on:April 01,2024

Treatment of advanced non-small cell lung cancer with driver mutations

by Higher Education PressGraphical abstract. Credit:Frontiers of Medicine(2023). DOI: 10.1007/s11684-022-0976-4Lung cancer is the leading cause of cancer-related death worldwide. Improved

Updated on: March 30,2024

Treatment of advanced non-small cell lung cancer with driver mutations

by Higher Education PressGraphical abstract. Credit:Frontiers of Medicine(2023). DOI: 10.1007/s11684-022-0976-4Lung cancer is the leading cause of cancer-related death worldwide. Improved

Updated on:March 30,2024

Implanted pump safely delivers chemo straight to brain in patients with brain cancer

byColumbia University Irving Medical CenterMRI scans show that chemotherapy delivered via the pump saturated the area in and around each patient's brain tumor. Top images show the brain befo

Updated on: January 02,2024

Implanted pump safely delivers chemo straight to brain in patients with brain cancer

byColumbia University Irving Medical CenterMRI scans show that chemotherapy delivered via the pump saturated the area in and around each patient's brain tumor. Top images show the brain befo

Updated on:January 02,2024

Study sheds light on how breast cancer cells evade immune surveillance and survive in lymph nodes

by Brandon Chase,Massachusetts General HospitalA molecule called MHC-II (seen here in green) disguises metastatic breast cancer cells (red), allowing them to invade the lymph nodes and take root

Updated on: February 18,2024

Study sheds light on how breast cancer cells evade immune surveillance and survive in lymph nodes

by Brandon Chase,Massachusetts General HospitalA molecule called MHC-II (seen here in green) disguises metastatic breast cancer cells (red), allowing them to invade the lymph nodes and take root

Updated on:February 18,2024

Exercise associated with benefit to patients with advanced colorectal cancer

by Dana-Farber Cancer InstituteDr. Meyerhardt is the clinical director of the Gastrointestinal Cancer Center at Dana-Farber Cancer Institute and the senior author of the study. Credit: Dana-Farbe

Updated on: May 05,2024

Exercise associated with benefit to patients with advanced colorectal cancer

by Dana-Farber Cancer InstituteDr. Meyerhardt is the clinical director of the Gastrointestinal Cancer Center at Dana-Farber Cancer Institute and the senior author of the study. Credit: Dana-Farbe

Updated on:May 05,2024

Researchers study cost-effectiveness of rectal cancer treatments

by Duane Bates,University of California, Los AngelesUCLA radiation therapists review a patient’s plan before setting the patient up for treatment. Credit: University of California, Los AngelesCo

Updated on: June 04,2024

Researchers study cost-effectiveness of rectal cancer treatments

by Duane Bates,University of California, Los AngelesUCLA radiation therapists review a patient’s plan before setting the patient up for treatment. Credit: University of California, Los AngelesCo

Updated on:June 04,2024

A non-coding RNA lasso catches proteins in breast cancer cells

by Lisbeth Heilesen,Aarhus UniversityThe authors show that the long non-coding RNA called A-ROD (Activating Regulator Of DKK1 expression) is only functional the moment it is released from chroma

Updated on: May 20,2024

A non-coding RNA lasso catches proteins in breast cancer cells

by Lisbeth Heilesen,Aarhus UniversityThe authors show that the long non-coding RNA called A-ROD (Activating Regulator Of DKK1 expression) is only functional the moment it is released from chroma

Updated on:May 20,2024

Bendamustine prior to CAR T-cell therapy in patients with refractory large B-cell lymphoma: Poorer treatment outcomes

byVall d'Hebron Institute of OncologyCredit: Pixabay/CC0 Public DomainTreatment with bendamustine prior to CAR T-cell therapy in patients with refractory large B-cell lymphoma associates wit

Updated on: December 28,2023

Bendamustine prior to CAR T-cell therapy in patients with refractory large B-cell lymphoma: Poorer treatment outcomes

byVall d'Hebron Institute of OncologyCredit: Pixabay/CC0 Public DomainTreatment with bendamustine prior to CAR T-cell therapy in patients with refractory large B-cell lymphoma associates wit

Updated on:December 28,2023