Selective protection of normal cells from chemotherapy, while killing drug-resistant cancer cells

by Impact JournalsCaspase inhibitors (CI) selectively protect normal cells from chemotherapy-induced apoptosis, without protection multidrug-resistant cancer cells. Flavopiridol (shown in red, as a cy

Updated on: January 15,2024

Selective protection of normal cells from chemotherapy, while killing drug-resistant cancer cells

by Impact JournalsCaspase inhibitors (CI) selectively protect normal cells from chemotherapy-induced apoptosis, without protection multidrug-resistant cancer cells. Flavopiridol (shown in red, as a cy

Updated on:January 15,2024

Critical Analysis of CDKN2A Deletion's Role in Lipid Metabolism Remodeling and Ferroptosis Sensitivity in Glioblastoma Multiforme

Updated on: September 21,2024

Critical Analysis of CDKN2A Deletion's Role in Lipid Metabolism Remodeling and Ferroptosis Sensitivity in Glioblastoma Multiforme

Updated on:September 21,2024

Study confirms curable state between single and widespread cancers

by University of Chicago Medical CenterRalph Weichselbaum, M.D., the Daniel K. Ludwig Distinguished Service Professor, chair of radiation and cellular oncology at UChicago and director of the Lud

Updated on: March 01,2024

Study confirms curable state between single and widespread cancers

by University of Chicago Medical CenterRalph Weichselbaum, M.D., the Daniel K. Ludwig Distinguished Service Professor, chair of radiation and cellular oncology at UChicago and director of the Lud

Updated on:March 01,2024

New leukemia drug is more effective and easier to use

by Loyola University Health SystemA Wright's stained bone marrow aspirate smear from a patient with precursor B-cell acute lymphoblastic leukemia. Credit: VashiDonsk/WikipediaA landmark study

Updated on: March 12,2024

New leukemia drug is more effective and easier to use

by Loyola University Health SystemA Wright's stained bone marrow aspirate smear from a patient with precursor B-cell acute lymphoblastic leukemia. Credit: VashiDonsk/WikipediaA landmark study

Updated on:March 12,2024

Researchers peer inside cells to spy on cancer's on-off switch

by Lisa Marshall,University of Colorado at BoulderCredit: University of Colorado at BoulderForty years after researchers first discovered it in fruit flies, a once-obscure cluster of proteins ca

Updated on: June 06,2024

Researchers peer inside cells to spy on cancer's on-off switch

by Lisa Marshall,University of Colorado at BoulderCredit: University of Colorado at BoulderForty years after researchers first discovered it in fruit flies, a once-obscure cluster of proteins ca

Updated on:June 06,2024

Researchers identify new way to make cancer self-destruct

by Perelman School of Medicine at the University of PennsylvaniaATF4 is at a point after both pathways come back together. Credit: Penn MedicineFor years, researchers have been trying to target a

Updated on: June 19,2024

Researchers identify new way to make cancer self-destruct

by Perelman School of Medicine at the University of PennsylvaniaATF4 is at a point after both pathways come back together. Credit: Penn MedicineFor years, researchers have been trying to target a

Updated on:June 19,2024

Fighting cancer on Earth and in space using high-energy protons

byUS Department of EnergyLeft: production rate as a function of proton energy of parent radioisotopes selenium-72 (Se-72) (1) & germanium-68 (Ge-68) (2). Right, a Positron Emission Tomograph

Updated on: December 28,2023

Fighting cancer on Earth and in space using high-energy protons

byUS Department of EnergyLeft: production rate as a function of proton energy of parent radioisotopes selenium-72 (Se-72) (1) & germanium-68 (Ge-68) (2). Right, a Positron Emission Tomograph

Updated on:December 28,2023

Study identifies new therapeutic target for tumor treatment

by Olivia Dimmer,Northwestern UniversityIntratumoral Tregcells have increased mRNA expression ofUsp22andUsp21.(AtoC) mRNA level of YFP+sorted Treg

Updated on: February 03,2024

Study identifies new therapeutic target for tumor treatment

by Olivia Dimmer,Northwestern UniversityIntratumoral Tregcells have increased mRNA expression ofUsp22andUsp21.(AtoC) mRNA level of YFP+sorted Treg

Updated on:February 03,2024

Blood cancers: Expert explains what you need to know

by Robin FosterBlood cancer is not a diagnosis anyone wants to receive, but understanding the different types of this disease and how best to catch them early is essential, one expert says.First, bloo

Updated on: November 10,2024

Blood cancers: Expert explains what you need to know

by Robin FosterBlood cancer is not a diagnosis anyone wants to receive, but understanding the different types of this disease and how best to catch them early is essential, one expert says.First, bloo

Updated on:November 10,2024

Predictive molecular biomarkers for determining neoadjuvant chemosensitivity in muscle invasive bladder cancer

by Impact Journals LLCVolcano plot of significant differentially expressed genes with the left volcano being the discovery cohort and validation cohort on the right. Credit:Oncotarget(2022

Updated on: January 02,2024

Predictive molecular biomarkers for determining neoadjuvant chemosensitivity in muscle invasive bladder cancer

by Impact Journals LLCVolcano plot of significant differentially expressed genes with the left volcano being the discovery cohort and validation cohort on the right. Credit:Oncotarget(2022

Updated on:January 02,2024

Research uncovers how to target 'sleeping' breast cancer cells and prevent relapse

byInstitute of Cancer ResearchModel: Endocrine therapy-induced dormancy is characterized by a consistent epigenetic reprogramming involving a global increase in histone repressive marks. The dor

Updated on: March 28,2024

Research uncovers how to target 'sleeping' breast cancer cells and prevent relapse

byInstitute of Cancer ResearchModel: Endocrine therapy-induced dormancy is characterized by a consistent epigenetic reprogramming involving a global increase in histone repressive marks. The dor

Updated on:March 28,2024

Prostate cancer testing in Sweden—a study on cost and effectiveness

byKarolinska InstitutetShuang Hao, PhD student at the Department of Medical Epidemiology and Biostatistics. Credit: Stefan ZimmermanProstate cancer constitutes an essential public health issue,

Updated on: January 03,2024

Prostate cancer testing in Sweden—a study on cost and effectiveness

byKarolinska InstitutetShuang Hao, PhD student at the Department of Medical Epidemiology and Biostatistics. Credit: Stefan ZimmermanProstate cancer constitutes an essential public health issue,

Updated on:January 03,2024