The 'wrong' connective tissue cells signal worse prognosis for breast cancer patients

by Lund UniversityDifferent types of fibroblasts in breast tumour tissue. Credit: Chris MadsenIn certain forms of cancer, connective tissue forms around and within the tumour. One previously unpr

Updated on: March 13,2024

The 'wrong' connective tissue cells signal worse prognosis for breast cancer patients

by Lund UniversityDifferent types of fibroblasts in breast tumour tissue. Credit: Chris MadsenIn certain forms of cancer, connective tissue forms around and within the tumour. One previously unpr

Updated on:March 13,2024

Researchers identify lethal molecular alterations after current therapies fail patients with metastatic melanoma

by University of California, Los AngelesCredit: Pixabay/CC0 Public DomainIn a new translational study from UCLA Jonsson Comprehensive Cancer Center, researchers analyzed genetic changes in the or

Updated on: January 30,2024

Researchers identify lethal molecular alterations after current therapies fail patients with metastatic melanoma

by University of California, Los AngelesCredit: Pixabay/CC0 Public DomainIn a new translational study from UCLA Jonsson Comprehensive Cancer Center, researchers analyzed genetic changes in the or

Updated on:January 30,2024

Adding tucatinib to drug combination extends survival for advanced HER2+ breast cancer patients

by University of Texas M. D. Anderson Cancer CenterCredit: CC0 Public DomainResearchers from The University of Texas MD Anderson Cancer Center today reported study results showing the addition of

Updated on: April 23,2024

Adding tucatinib to drug combination extends survival for advanced HER2+ breast cancer patients

by University of Texas M. D. Anderson Cancer CenterCredit: CC0 Public DomainResearchers from The University of Texas MD Anderson Cancer Center today reported study results showing the addition of

Updated on:April 23,2024

Study gives new insight into how cancer metastasizes to the brain

by The Wistar InstituteIFN signaling is activated in brain metastasis.a–cIFN signaling is activated in both human astrocytes and MDA231-BrM cells by coculture in vitro.N = 2 bio

Updated on: February 20,2024

Study gives new insight into how cancer metastasizes to the brain

by The Wistar InstituteIFN signaling is activated in brain metastasis.a–cIFN signaling is activated in both human astrocytes and MDA231-BrM cells by coculture in vitro.N = 2 bio

Updated on:February 20,2024

ASCO: low-dose chemo benefits advanced gastroesophageal cancer

(HealthDay)—For frail and elderly patients with advanced gastroesophageal cancer (aGOAC), low-dose chemotherapy is noninferior to high-dose chemotherapy for progression-free survival, according to a s

Updated on: March 30,2024

ASCO: low-dose chemo benefits advanced gastroesophageal cancer

(HealthDay)—For frail and elderly patients with advanced gastroesophageal cancer (aGOAC), low-dose chemotherapy is noninferior to high-dose chemotherapy for progression-free survival, according to a s

Updated on:March 30,2024

Some lymphomas become resistant to treatment. Gene discovery may offer path to overcome it.

by Will Cushman,University of Wisconsin-MadisonA confocal microscope image of lymphoma cells. It shows mitochondrial localization (red) around cell nuclei (blue). Credit: Lixin Rui, University o

Updated on: March 30,2024

Some lymphomas become resistant to treatment. Gene discovery may offer path to overcome it.

by Will Cushman,University of Wisconsin-MadisonA confocal microscope image of lymphoma cells. It shows mitochondrial localization (red) around cell nuclei (blue). Credit: Lixin Rui, University o

Updated on:March 30,2024

A new drug target identified for diseases associated with leukemia-causing virus

by Christine Yu,Pennsylvania State UniversityKDR inhibition induces autophagic/lysosomal degradation of Tax. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-49737-5A team

Updated on: August 06,2024

A new drug target identified for diseases associated with leukemia-causing virus

by Christine Yu,Pennsylvania State UniversityKDR inhibition induces autophagic/lysosomal degradation of Tax. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-49737-5A team

Updated on:August 06,2024

Circulating tumor cell count guidance may improve long-term outcomes for patients with metastatic breast cancer

byAmerican Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainThe use of circulating tumor cell (CTC) count to guide the choice between chemotherapy and endocrine therapy as first-

Updated on: January 22,2024

Circulating tumor cell count guidance may improve long-term outcomes for patients with metastatic breast cancer

byAmerican Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainThe use of circulating tumor cell (CTC) count to guide the choice between chemotherapy and endocrine therapy as first-

Updated on:January 22,2024

Novel liquid biopsy methodology enables monitoring of disease evolution in patients with metastatic prostate cancer

byVall d'Hebron Institute of OncologyGraphical abstract. Credit:Cancer Cell(2024). DOI: 10.1016/j.ccell.2024.06.003Published today inCancer Cell, results of astudy&nb

Updated on: July 09,2024

Novel liquid biopsy methodology enables monitoring of disease evolution in patients with metastatic prostate cancer

byVall d'Hebron Institute of OncologyGraphical abstract. Credit:Cancer Cell(2024). DOI: 10.1016/j.ccell.2024.06.003Published today inCancer Cell, results of astudy&nb

Updated on:July 09,2024

Artificial intelligence analysis of DNA fragmentomes and protein biomarkers noninvasively detects ovarian cancer

byAmerican Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainA blood-based machine learning assay that combines cell-free DNA (cfDNA) fragment patterns and levels of the proteins

Updated on: April 30,2024

Artificial intelligence analysis of DNA fragmentomes and protein biomarkers noninvasively detects ovarian cancer

byAmerican Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainA blood-based machine learning assay that combines cell-free DNA (cfDNA) fragment patterns and levels of the proteins

Updated on:April 30,2024

Researchers discover how bacteria make pancreatic cancer cells grow and move

by Virginia TechPancreatic cancer cells (blue) growing as a sphere encased in membranes (red). Credit: National Cancer InstituteVirginia Tech researchers from the Department of Biomedical Enginee

Updated on: January 30,2024

Researchers discover how bacteria make pancreatic cancer cells grow and move

by Virginia TechPancreatic cancer cells (blue) growing as a sphere encased in membranes (red). Credit: National Cancer InstituteVirginia Tech researchers from the Department of Biomedical Enginee

Updated on:January 30,2024

Mechanism facilitates brain metastasis from breast cancer and melanoma by inducing neuroinflammation

byTel-Aviv UniversityBrain metastatic burden and survival in mice injected with breast cancer cells. a. Experimental scheme analyzed in (b,c). b. Survival curve analysis of WT and Lcn2-/-m

Updated on: January 07,2024

Mechanism facilitates brain metastasis from breast cancer and melanoma by inducing neuroinflammation

byTel-Aviv UniversityBrain metastatic burden and survival in mice injected with breast cancer cells. a. Experimental scheme analyzed in (b,c). b. Survival curve analysis of WT and Lcn2-/-m

Updated on:January 07,2024