Breakthrough brings potential glioblastoma drug into focus

byKeck School of Medicine of USCA new type of small molecule drug, the first to target circadian clock proteins as a way to treat glioblastoma, is now in phase 1 clinical trials. Credit: Issey T

Updated on: January 07,2024

Breakthrough brings potential glioblastoma drug into focus

byKeck School of Medicine of USCA new type of small molecule drug, the first to target circadian clock proteins as a way to treat glioblastoma, is now in phase 1 clinical trials. Credit: Issey T

Updated on:January 07,2024

Toward a personalized approach to the study and treatment of bone cancers

by Lund UniversityPrimary acute myeloid leukemia cells preferentially home and engraft in MSOD-B hOss.a, Experimental scheme of AML patient sample transplantation. b, Representative histological

Updated on: February 20,2024

Toward a personalized approach to the study and treatment of bone cancers

by Lund UniversityPrimary acute myeloid leukemia cells preferentially home and engraft in MSOD-B hOss.a, Experimental scheme of AML patient sample transplantation. b, Representative histological

Updated on:February 20,2024

Microcalcification 'fingerprints' can yield info about cancer

byCornell UniversityLeft, a pathology stain of a ductal carcinoma, showing cells and connective tissue. Right, a Raman mapping of the calcification, which was captured by a technique that detect

Updated on: January 08,2024

Microcalcification 'fingerprints' can yield info about cancer

byCornell UniversityLeft, a pathology stain of a ductal carcinoma, showing cells and connective tissue. Right, a Raman mapping of the calcification, which was captured by a technique that detect

Updated on:January 08,2024

Researchers reveal role of PPDPF in development of mutant KRAS-driven pancreatic ductal adenocarcinoma

by Liu Jia,Chinese Academy of SciencesSchematic representation demonstrating the function of PPDPF in KRAS activation. Credit: Dr. XIE Dong's groupA recent study by Dr. Xie Dong's group

Updated on: February 20,2024

Researchers reveal role of PPDPF in development of mutant KRAS-driven pancreatic ductal adenocarcinoma

by Liu Jia,Chinese Academy of SciencesSchematic representation demonstrating the function of PPDPF in KRAS activation. Credit: Dr. XIE Dong's groupA recent study by Dr. Xie Dong's group

Updated on:February 20,2024

Tumor ammonia levels inhibit T cell growth, impact immunotherapy: Study

by Anna Megdell,University of MichiganGraphical abstract. Credit:Journal of Clinical Investigation(2021). DOI: 10.1172/JCI143691High levels of ammonia in tumors leads to fewer T cell

Updated on: January 21,2024

Tumor ammonia levels inhibit T cell growth, impact immunotherapy: Study

by Anna Megdell,University of MichiganGraphical abstract. Credit:Journal of Clinical Investigation(2021). DOI: 10.1172/JCI143691High levels of ammonia in tumors leads to fewer T cell

Updated on:January 21,2024

Researchers discover new tool for improving pancreatic cancer care

by Champalimaud Centre for the UnknownCredit: Unsplash/CC0 Public DomainThe statistics for pancreatic cancer are sobering. With a five-year survival rate of only 9%, incidence of the most common type,

Updated on: February 23,2024

Researchers discover new tool for improving pancreatic cancer care

by Champalimaud Centre for the UnknownCredit: Unsplash/CC0 Public DomainThe statistics for pancreatic cancer are sobering. With a five-year survival rate of only 9%, incidence of the most common type,

Updated on:February 23,2024

One lung cancer drug receives NHS England approval, while another is rejected

by Cancer Research UKCredit: CC0 Public DomainA targeted drug has been accepted for routine use on the NHS in England for some adults with untreated, advanced lung cancer. But another precision d

Updated on: May 20,2024

One lung cancer drug receives NHS England approval, while another is rejected

by Cancer Research UKCredit: CC0 Public DomainA targeted drug has been accepted for routine use on the NHS in England for some adults with untreated, advanced lung cancer. But another precision d

Updated on:May 20,2024

Immune landscape and response to oncolytic virus-based immunotherapy

by Frontiers JournalsCredit:Frontiers of Medicine(2024). DOI: 10.1007/s11684-023-1048-0Oncolytic virus (OV)-based immunotherapy has emerged as a promising strategy for cancer treatment, of

Updated on: August 28,2024

Immune landscape and response to oncolytic virus-based immunotherapy

by Frontiers JournalsCredit:Frontiers of Medicine(2024). DOI: 10.1007/s11684-023-1048-0Oncolytic virus (OV)-based immunotherapy has emerged as a promising strategy for cancer treatment, of

Updated on:August 28,2024

Study reinforces potential use of zika virus to combat prostate cancer but points to possible side-effect

by Julia Moióli,FAPESPAbstract. Credit:Journal of Proteome Research(2022). DOI: 10.1021/acs.jproteome.2c00630Preclinical trials have shown that zika virus can inhibit the spread of p

Updated on: January 28,2024

Study reinforces potential use of zika virus to combat prostate cancer but points to possible side-effect

by Julia Moióli,FAPESPAbstract. Credit:Journal of Proteome Research(2022). DOI: 10.1021/acs.jproteome.2c00630Preclinical trials have shown that zika virus can inhibit the spread of p

Updated on:January 28,2024

Researchers report encouraging immunotherapy option for relapsed myeloma patients

by The Mount Sinai HospitalTreatment breakdown of the multiple myeloma patient cohort. (A) Flow chart showing that the initial retrospective query yielded 115 RRMM patients enrolled on a BiAb cli

Updated on: February 18,2024

Researchers report encouraging immunotherapy option for relapsed myeloma patients

by The Mount Sinai HospitalTreatment breakdown of the multiple myeloma patient cohort. (A) Flow chart showing that the initial retrospective query yielded 115 RRMM patients enrolled on a BiAb cli

Updated on:February 18,2024

Breast MRI effective at detecting cancer in dense breasts, finds study

byRadiological Society of North AmericaForest plots show the incremental cancer detection rate (CDR) per 1000 screenings per modality. (A) Studies with handheld US. (B) Studies with automated wh

Updated on: January 23,2024

Breast MRI effective at detecting cancer in dense breasts, finds study

byRadiological Society of North AmericaForest plots show the incremental cancer detection rate (CDR) per 1000 screenings per modality. (A) Studies with handheld US. (B) Studies with automated wh

Updated on:January 23,2024

Researchers revisit potent drug as promising treatment for acute leukemia

by National University of SingaporeChemical screening using the GIMAP enhancer reporter system. (A) Overview of the chemical screening strategy. Using a liquid handling workstation, 2,961 compoun

Updated on: February 03,2024

Researchers revisit potent drug as promising treatment for acute leukemia

by National University of SingaporeChemical screening using the GIMAP enhancer reporter system. (A) Overview of the chemical screening strategy. Using a liquid handling workstation, 2,961 compoun

Updated on:February 03,2024