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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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ASH: A+AVD beats ABVD for advanced Hodgkin's lymphoma

ASH: A+AVD beats ABVD for advanced Hodgkin's lymphoma

(HealthDay)—For patients with advanced-stage Hodgkin's lymphoma, brentuximab vedotin, doxorubicin, vinblastine, and dacarbazine (A+AVD) have superior efficacy to doxorubicin, bleomycin, vinblastin

ASH: A+AVD beats ABVD for advanced Hodgkin's lymphoma

(HealthDay)—For patients with advanced-stage Hodgkin's lymphoma, brentuximab vedotin, doxorubicin, vinblastine, and dacarbazine (A+AVD) have superior efficacy to doxorubicin, bleomycin, vinblastin
Maternal obesity linked to childhood cancer

Maternal obesity linked to childhood cancer

by University of PittsburghCredit: CC0 Public DomainA new study from the University of Pittsburgh Graduate School of Public Health and UPMC Hillman Cancer Center found that children born to obese

Maternal obesity linked to childhood cancer

by University of PittsburghCredit: CC0 Public DomainA new study from the University of Pittsburgh Graduate School of Public Health and UPMC Hillman Cancer Center found that children born to obese
Treatment of advanced non-small cell lung cancer with driver mutations

Treatment of advanced non-small cell lung cancer with driver mutations

by Higher Education PressGraphical abstract. Credit:Frontiers of Medicine(2023). DOI: 10.1007/s11684-022-0976-4Lung cancer is the leading cause of cancer-related death worldwide. Improved

Treatment of advanced non-small cell lung cancer with driver mutations

by Higher Education PressGraphical abstract. Credit:Frontiers of Medicine(2023). DOI: 10.1007/s11684-022-0976-4Lung cancer is the leading cause of cancer-related death worldwide. Improved
Breakthrough in understanding of how cancer spreads could lead to better treatments

Breakthrough in understanding of how cancer spreads could lead to better treatments

by Cancer Research UKNALCN loss-of-function in aggressive cancers.a, Differential gene expression between normal PROM1+gastric cells andP1KP-GAC cells (downregulated ion channels are

Breakthrough in understanding of how cancer spreads could lead to better treatments

by Cancer Research UKNALCN loss-of-function in aggressive cancers.a, Differential gene expression between normal PROM1+gastric cells andP1KP-GAC cells (downregulated ion channels are
Immunotherapy for blood cancer: Remote destruction of tumor cells demonstrated

Immunotherapy for blood cancer: Remote destruction of tumor cells demonstrated

byPasteur InstituteGating strategies for flow cytometry identification of pro-B-cell tumors. (a) Gating strategy for identifying pro-B-cell tumors expressing the FRET-based caspase 3 reporter (n

Immunotherapy for blood cancer: Remote destruction of tumor cells demonstrated

byPasteur InstituteGating strategies for flow cytometry identification of pro-B-cell tumors. (a) Gating strategy for identifying pro-B-cell tumors expressing the FRET-based caspase 3 reporter (n
Drug mechanism opens door for new anti-cancer immunotherapies

Drug mechanism opens door for new anti-cancer immunotherapies

by King's College LondonCredit: CC0 Public DomainResearchers have revealed a new mechanism of targeted drug treatment used against chronic lymphocytic leukemia, through the promotion of immun

Drug mechanism opens door for new anti-cancer immunotherapies

by King's College LondonCredit: CC0 Public DomainResearchers have revealed a new mechanism of targeted drug treatment used against chronic lymphocytic leukemia, through the promotion of immun
New mammogram rule gives women more details to guard against breast cancer

New mammogram rule gives women more details to guard against breast cancer

by Helena Oliviero, The Atlanta Journal-ConstitutionCredit: Unsplash/CC0 Public DomainA new federal rule takes effect Tuesday that could potentially help more women spot breast cancer earlier. The FDA

New mammogram rule gives women more details to guard against breast cancer

by Helena Oliviero, The Atlanta Journal-ConstitutionCredit: Unsplash/CC0 Public DomainA new federal rule takes effect Tuesday that could potentially help more women spot breast cancer earlier. The FDA
Team establishes a large collection of cholangiocarcinoma models for preclinical drug evaluation and biomarker discovery

Team establishes a large collection of cholangiocarcinoma models for preclinical drug evaluation and biomarker discovery

by Vall d'Hebron Institute of OncologyCholangiocarcinomas (CCAs) are a highly aggressive and diverse group of malignancies of the biliary tract that currently account for 15% of all liver cancers

Team establishes a large collection of cholangiocarcinoma models for preclinical drug evaluation and biomarker discovery

by Vall d'Hebron Institute of OncologyCholangiocarcinomas (CCAs) are a highly aggressive and diverse group of malignancies of the biliary tract that currently account for 15% of all liver cancers
Researchers identify drug resistance factors for advanced prostate cancer

Researchers identify drug resistance factors for advanced prostate cancer

by Mayo ClinicThe DNA/RNA processing used both single sample and multi-sample analyses as part of the processing. Credit:Molecular Cancer Research(2022). DOI: 10.1158/1541-7786.MCR-22

Researchers identify drug resistance factors for advanced prostate cancer

by Mayo ClinicThe DNA/RNA processing used both single sample and multi-sample analyses as part of the processing. Credit:Molecular Cancer Research(2022). DOI: 10.1158/1541-7786.MCR-22
Small molecule inhibitors show early-stage promise against YAP fusion-driven cancers

Small molecule inhibitors show early-stage promise against YAP fusion-driven cancers

byCincinnati Children's Hospital Medical CenterIn an early proof-of-concept success, a team led by experts at Cincinnati Children's reports that mice induced to develop brain tumors feat

Small molecule inhibitors show early-stage promise against YAP fusion-driven cancers

byCincinnati Children's Hospital Medical CenterIn an early proof-of-concept success, a team led by experts at Cincinnati Children's reports that mice induced to develop brain tumors feat
Researchers develop new machete technique to slice into cancer genome and study copy number alterations

Researchers develop new machete technique to slice into cancer genome and study copy number alterations

by Memorial Sloan Kettering Cancer CenterMACHETE enables efficient engineering of genomic deletions. a, Schematic of the MACHETE approach. WT, wild type; HA, homology arm; Puro, puromycin; pA, po

Researchers develop new machete technique to slice into cancer genome and study copy number alterations

by Memorial Sloan Kettering Cancer CenterMACHETE enables efficient engineering of genomic deletions. a, Schematic of the MACHETE approach. WT, wild type; HA, homology arm; Puro, puromycin; pA, po
Novel inherited variants may raise risk for Hodgkin lymphoma

Novel inherited variants may raise risk for Hodgkin lymphoma

Novel coding and noncoding gene variants have been identified that may increase the risk for developing Hodgkin lymphoma (HL), according to a study published online Aug. 20 inBlood.Jamie E. Fler

Novel inherited variants may raise risk for Hodgkin lymphoma

Novel coding and noncoding gene variants have been identified that may increase the risk for developing Hodgkin lymphoma (HL), according to a study published online Aug. 20 inBlood.Jamie E. Fler