Blocking inflammatory pathway key to preventing brain metastasis from melanoma

by Tel Aviv UniversityMelanoma. Credit: Wikimedia Commons/National Cancer InstituteBrain metastases are among the deadliest tumor metastases, with a median survival period of less than one year,

Updated on: April 01,2024

Blocking inflammatory pathway key to preventing brain metastasis from melanoma

by Tel Aviv UniversityMelanoma. Credit: Wikimedia Commons/National Cancer InstituteBrain metastases are among the deadliest tumor metastases, with a median survival period of less than one year,

Updated on:April 01,2024

How melanoma cells escape oxidative stress to metastasize

byWeill Cornell Medical CollegeResearchers have discovered how some melanoma cells defend against oxidative stress and metastasize to new organs. The anatomy of metastatic melanoma cells picture

Updated on: November 11,2024

How melanoma cells escape oxidative stress to metastasize

byWeill Cornell Medical CollegeResearchers have discovered how some melanoma cells defend against oxidative stress and metastasize to new organs. The anatomy of metastatic melanoma cells picture

Updated on:November 11,2024

Primary pancreatic organoid tumor models for high-throughput phenotypic drug screening

by SLAS (Society for Laboratory Automation and Screening)A Z-stack image was obtained after staining nuclei with Hoechst using confocal microscopy at 5 micron intervals and then assembled using ImageJ

Updated on: May 09,2024

Primary pancreatic organoid tumor models for high-throughput phenotypic drug screening

by SLAS (Society for Laboratory Automation and Screening)A Z-stack image was obtained after staining nuclei with Hoechst using confocal microscopy at 5 micron intervals and then assembled using ImageJ

Updated on:May 09,2024

Efficient removal of abnormal myelin allows survival of nerve fibers targeted by adaptive immune cells

by Julius-Maximilians-Universität WürzburgElectronmicroscopic pictures of white matter axons in healthy control mice (top) and mice with different myelin gene defects. Axons that remain wrapped w

Updated on: May 11,2024

Efficient removal of abnormal myelin allows survival of nerve fibers targeted by adaptive immune cells

by Julius-Maximilians-Universität WürzburgElectronmicroscopic pictures of white matter axons in healthy control mice (top) and mice with different myelin gene defects. Axons that remain wrapped w

Updated on:May 11,2024

Have recent efforts successfully boosted adolescent and young adult enrollment in cancer clinical trials?

byWileyDistribution of trial types by year. For each calendar year, the number of actively accruing trials for which adolescent and young adult patients were eligible is represented as a stacked

Updated on: January 21,2024

Have recent efforts successfully boosted adolescent and young adult enrollment in cancer clinical trials?

byWileyDistribution of trial types by year. For each calendar year, the number of actively accruing trials for which adolescent and young adult patients were eligible is represented as a stacked

Updated on:January 21,2024

Using AI during cancer-screening results in more recommended controls

by Mathilde Coraline Aarvold Bakke,University of OsloGraphical abstract. Credit:Clinical Gastroenterology and Hepatology(2022). DOI: 10.1016/j.cgh.2022.08.022A polyp is a small growt

Updated on: January 29,2024

Using AI during cancer-screening results in more recommended controls

by Mathilde Coraline Aarvold Bakke,University of OsloGraphical abstract. Credit:Clinical Gastroenterology and Hepatology(2022). DOI: 10.1016/j.cgh.2022.08.022A polyp is a small growt

Updated on:January 29,2024

Researchers develop AI platform to rapidly identify optimal personalised drug combinations for myeloma patients

by National University of SingaporeA multidisciplinary team of researchers from NUShas developed an AI technology platform that could enable doctors to prescribe personalised treatments for

Updated on: June 08,2024

Researchers develop AI platform to rapidly identify optimal personalised drug combinations for myeloma patients

by National University of SingaporeA multidisciplinary team of researchers from NUShas developed an AI technology platform that could enable doctors to prescribe personalised treatments for

Updated on:June 08,2024

Researchers identify possible approach to prevent cancer from evolving to resist treatment

by University of California, Los AngelesSingle-agent inhibitory potencies in human melanoma, PDAC, and NSCLC clonogenic growth assays. A to G, Long-term clonogenic growth of indicated BRAFV600MUT

Updated on: February 18,2024

Researchers identify possible approach to prevent cancer from evolving to resist treatment

by University of California, Los AngelesSingle-agent inhibitory potencies in human melanoma, PDAC, and NSCLC clonogenic growth assays. A to G, Long-term clonogenic growth of indicated BRAFV600MUT

Updated on:February 18,2024

2023 cisplatin shortage tied to use of alternatives for head, neck cancer

by Lori SolomonThe 2023 cisplatin shortage led to a shift in utilization to alternative therapies for head and neck cancer (HNC), resulting in significant cost increases, according to a study presente

Updated on: October 18,2024

2023 cisplatin shortage tied to use of alternatives for head, neck cancer

by Lori SolomonThe 2023 cisplatin shortage led to a shift in utilization to alternative therapies for head and neck cancer (HNC), resulting in significant cost increases, according to a study presente

Updated on:October 18,2024

Study explores current pharmacy practice in cardio-oncology

by Milana Madzarac,University of WaterlooCredit: Unsplash/CC0 Public DomainA structured support system for oncology patients is one of the most important aspects during a difficult time in someo

Updated on: February 03,2024

Study explores current pharmacy practice in cardio-oncology

by Milana Madzarac,University of WaterlooCredit: Unsplash/CC0 Public DomainA structured support system for oncology patients is one of the most important aspects during a difficult time in someo

Updated on:February 03,2024

Newly developed inhibitor shows potential for prostate cancer

JANUARY 9, 2024byAlbert Ludwigs University of FreiburgIdentification of a bi-substrate inhibitor of KMT9.aChemical structure of compound1awith predicted binding mode.&nbs

Updated on: March 25,2024

Newly developed inhibitor shows potential for prostate cancer

JANUARY 9, 2024byAlbert Ludwigs University of FreiburgIdentification of a bi-substrate inhibitor of KMT9.aChemical structure of compound1awith predicted binding mode.&nbs

Updated on:March 25,2024

Study reveals insights into DDX41 protein's role in blood cancer pathogenesis

by JooHyeon Heo,Ulsan National Institute of Science and TechnologyA schematic image showing the impact of DDX41 mutations on MDS patients. Credit: Won Chan Hwang et al/Ulsan National Institute o

Updated on: April 28,2024

Study reveals insights into DDX41 protein's role in blood cancer pathogenesis

by JooHyeon Heo,Ulsan National Institute of Science and TechnologyA schematic image showing the impact of DDX41 mutations on MDS patients. Credit: Won Chan Hwang et al/Ulsan National Institute o

Updated on:April 28,2024