Researchers use machine learning to unlock the genomic code in clinical cancer samples

by University of HelsinkiMutational signatures of formalin exposure. a C>T FFPE-only mutation count increases with formalin fixation time. We observed this increase in both unrepaired and repa

Updated on: February 18,2024 20

Researchers use machine learning to unlock the genomic code in clinical cancer samples

by University of HelsinkiMutational signatures of formalin exposure. a C>T FFPE-only mutation count increases with formalin fixation time. We observed this increase in both unrepaired and repa

Updated on:February 18,2024 20

Patients coping with mesothelioma experienced higher levels of toxicity on CheckMate743 regimen than reported in trials

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainBased on results from the CheckMate743 trial, the dual regimen of ipilimumab and nivolumab is the standard of

Updated on: April 10,2024 16

Patients coping with mesothelioma experienced higher levels of toxicity on CheckMate743 regimen than reported in trials

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainBased on results from the CheckMate743 trial, the dual regimen of ipilimumab and nivolumab is the standard of

Updated on:April 10,2024 16

Shades of grey reveal breast tumours

by David Bradley,InderscienceMammograms showing a normal breast (left) and a breast with cancer (right). Credit: Public DomainBreast cancer is the second most common cancer in women. Mammography

Updated on: March 01,2024 17

Shades of grey reveal breast tumours

by David Bradley,InderscienceMammograms showing a normal breast (left) and a breast with cancer (right). Credit: Public DomainBreast cancer is the second most common cancer in women. Mammography

Updated on:March 01,2024 17

'Positive' trial for Pfizer-BioNTech COVID-flu jab

Credit: Unsplash/CC0 Public DomainGermany's BioNTech and US pharmaceutical giant Pfizer on Thursday announced "positive" results from initial trials of their combined mRNA vaccine agains

Updated on: March 01,2024 17

'Positive' trial for Pfizer-BioNTech COVID-flu jab

Credit: Unsplash/CC0 Public DomainGermany's BioNTech and US pharmaceutical giant Pfizer on Thursday announced "positive" results from initial trials of their combined mRNA vaccine agains

Updated on:March 01,2024 17

The hitchhiker's guide to defeating glioblastoma

by Brigham and Women's HospitalGlioblastoma (histology slide). Credit: Wikipedia/CC BY-SA 3.0In cancer therapeutics research, microRNAs—tiny strings of nucleotides that get churned out inside

Updated on: April 18,2024 10

The hitchhiker's guide to defeating glioblastoma

by Brigham and Women's HospitalGlioblastoma (histology slide). Credit: Wikipedia/CC BY-SA 3.0In cancer therapeutics research, microRNAs—tiny strings of nucleotides that get churned out inside

Updated on:April 18,2024 10

Medicaid expansion in Southern states associated with earlier and more comprehensive breast cancer treatment

byAmerican College of SurgeonsCredit: Unsplash/CC0 Public DomainPatients diagnosed with invasive breast cancer in a Southern state that expanded access to Medicaid were more likely to receive tr

Updated on: January 02,2024 8

Medicaid expansion in Southern states associated with earlier and more comprehensive breast cancer treatment

byAmerican College of SurgeonsCredit: Unsplash/CC0 Public DomainPatients diagnosed with invasive breast cancer in a Southern state that expanded access to Medicaid were more likely to receive tr

Updated on:January 02,2024 8

Without 'yoga and chardonnay' leukemia stem cells are stressed to death

by CU Anschutz Medical CampusCraig T. Jordan, Ph.D., and colleagues show that blocking the stress-relief of mitophagy kills leukemia stem cells without harming healthy blood stem cells. Credit: U

Updated on: March 01,2024 14

Without 'yoga and chardonnay' leukemia stem cells are stressed to death

by CU Anschutz Medical CampusCraig T. Jordan, Ph.D., and colleagues show that blocking the stress-relief of mitophagy kills leukemia stem cells without harming healthy blood stem cells. Credit: U

Updated on:March 01,2024 14

Pattern of hospital visits offers clue to spotting people at risk of myeloma

by National Cancer Research InstituteMicrograph of a plasmacytoma, the histologic correlate of multiple myeloma. H&E stain. Credit: Wikipedia/CC BY-SA 3.0A condition that can progress to myeloma c

Updated on: May 13,2024 6

Pattern of hospital visits offers clue to spotting people at risk of myeloma

by National Cancer Research InstituteMicrograph of a plasmacytoma, the histologic correlate of multiple myeloma. H&E stain. Credit: Wikipedia/CC BY-SA 3.0A condition that can progress to myeloma c

Updated on:May 13,2024 6

Dietary factors affecting gut microbiome may influence response to immunotherapy in melanoma patients

by American Association for Cancer ResearchCredit: CC0 Public DomainAmong melanoma patients treated with anti-PD-1 immunotherapy, consumption of a high-fiber diet was associated with higher gut m

Updated on: May 11,2024 8

Dietary factors affecting gut microbiome may influence response to immunotherapy in melanoma patients

by American Association for Cancer ResearchCredit: CC0 Public DomainAmong melanoma patients treated with anti-PD-1 immunotherapy, consumption of a high-fiber diet was associated with higher gut m

Updated on:May 11,2024 8

Moving the needle on monitoring skin cancer

by Benjamin Boettner,Harvard UniversityThe team engineered a strategy for monitoring the immunological responses to a newly devised, locally applied immunotherapy against melanoma. The therapy a

Updated on: February 01,2024 13

Moving the needle on monitoring skin cancer

by Benjamin Boettner,Harvard UniversityThe team engineered a strategy for monitoring the immunological responses to a newly devised, locally applied immunotherapy against melanoma. The therapy a

Updated on:February 01,2024 13

New research casts doubt on role of fungus in driving pancreatic cancer

byDuke University Medical CenterAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainFour years ago, a report that a common species of fungu

Updated on: January 12,2024 12

New research casts doubt on role of fungus in driving pancreatic cancer

byDuke University Medical CenterAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainFour years ago, a report that a common species of fungu

Updated on:January 12,2024 12

Study suggests tumor mutational load may be useful metric to predict response to checkpoint-inhibitor immunotherapy

by Bob Yirka , Medical XpressCredit: CC0 Public DomainA large team of researchers affiliated with Sloan Kettering Cancer Center, Weill Cornell Medical Center and Columbia University Medical Center has

Updated on: March 08,2024 10

Study suggests tumor mutational load may be useful metric to predict response to checkpoint-inhibitor immunotherapy

by Bob Yirka , Medical XpressCredit: CC0 Public DomainA large team of researchers affiliated with Sloan Kettering Cancer Center, Weill Cornell Medical Center and Columbia University Medical Center has

Updated on:March 08,2024 10